Quinoa thrives at 4,000m altitude where many crops struggle. Heat Shock Proteins helps protect plant cells from environmental stress. These molecular mechanisms in traditional crops may inform climate-resilient agriculture strategies. 💻🧪 More info: proteinswebteam.github.io/interpro-blo...

Interested in studying Parkinson's disease? Have a look at our blog post below

📢 Happy to announce that Ensembl 115 and Ensembl Genomes 62 are out! This release features ~120000 new protein coding transcripts in human GRCh38, 2 new cattle, 7 new plants and 20 new metazoa! 🧬🐮 🫛🪲 Read more here ➡️ zurl.co/poyXM

Feature Spotlight: Taxonomy Sunburst Discover the taxonomic breadth of your InterPro entry at a glance with our dynamic sunburst chart! 🕸️ 💻🧪🧬

InterProScan 6 (beta) is here 🎉 A Nextflow-powered, containerised overhaul for scalable, reproducible protein annotation—decoupled software/data, automated data handling, and smoother runs across HPC and cloud. Feedback welcome! github.com/ebi-pf-team/... 💻🧪🧬

🧬 The InterPro/Pfam team will be presenting at #ISMB2025 next week in Liverpool! 🎤 Multiple talks & 📊 posters on protein analysis & classification 💻🧪

🧬 The InterPro/Pfam team will be presenting at #ISMB2025 next week in Liverpool! Join us July 20-24 at the world's largest #bioinformatics conference! #ISMBECCB2025 #ProteinAnalysis #ComputationalBiology 💻🧪

🧬✨ Excited to present at @jobim2025.bsky.social this week in Bordeaux! 🎤 Talk 08/07 16:50, amphi E: Pfam: embracing AI/ML by @typhainepl.bsky.social 📊 Poster #97: InterPro: Accelerating Protein Annotation with AI by @matthiasblum.bsky.social 💻🧪

Level up your protein prediction skills with the updated EMBL-EBI Training AlphaFold practical course. Now featuring #AlphaFold Server and AlphaFold 3. Start your training today: www.ebi.ac.uk/training/onl... AlphaFold, developed by @ebi.embl.org‬ and Google DeepMind.

Does taste depend on our genes? Discover how variations in taste receptors—from TAS2Rs that gate bitterness to olfactory genes that make cilantro taste soapy—and even pain receptors for spice shape what we love (and hate) on our plates. Read more: proteinswebteam.github.io/interpro-blo... 💻🧪👅🧬

🚀 InterPro 106.0 is now live! ✨ Updated to Pfam 37.4 ✨ 683 new entries added ✨ Enhanced protein classification coverage Explore the latest annotations and discover new protein insights. Explore it now: interpro.ebi.ac.uk 💻🧪🧬 #Bioinformatics #ProteinScience #Pfam #EMBLEBI

What’s new in the redesigned PDBe entry pages? 🧪 Cleaner layout 🧪 Interactive 3D viewers 🧪 Contextual annotations 🧪 Easier navigation See for yourself: wwwdev.ebi.ac.uk/pdbe/entry/p... #PDBeBeta #Bioinformatics #Biochemistry #Science

InterPro just got one of its biggest updates ever. Now with 1.8 billion AI-driven protein annotations, AlphaFold-based TED domains, and viral proteins from the Big Fantastic Virus Database (BFVD). See it all at www.ebi.ac.uk/interpro 🖥️🧬 @interprodb.bsky.social

🦠🧬Exciting news! BFVD predicted viral protein structures are now available in @InterProDB! For the first time, explore InterPro functional annotations directly on 3D structures of viral proteins not covered by AlphaFold DB. This bridges a critical gap in structural virology research.

We are saddened to hear of the passing of Daniel Kahn, the creator of the ProDom database. His pioneering work in protein domain classification laid important groundwork for InterPro and the wider bioinformatics community. We honour his lasting contributions. 🧬🕊️

🧬 MAJOR UPDATE: InterPro-N matches now available in InterPro! 1.8 billion AI-driven protein annotations developed with Google DeepMind are now live. ✨ Look for the sparkles icon to identify them 📊 Options menu lets you view: InterPro only | InterPro-N-only | Stacked 💻🧪

🔍 NEW: TED domains in InterPro 105.0! For the first time, see AlphaFold-derived structural domains directly alongside InterPro annotations in one powerful visualisation. Bridging the sequence-structure divide in protein analysis. 💻🧪 Explore now: www.ebi.ac.uk/interpro/pro...

📝 Check out our new blog post highlighting the groundbreaking features in InterPro 105.0! Learn how InterPro-N, TED domains and viral protein structures are transforming protein classification: ebi.ac.uk/about/news/u...

📢InterPro release 105.0 is live! ✨Update to Pfam 37.3, PROSITE patterns 2025_01 PROSITE profiles 2025_01 and HAMAP 2025_01 ✨342 new entries ✨Addition of InterPro-N annotations ✨Addition of BFVD structure predictions from @martinsteinegger.bsky.social's lab Have a look: ebi.ac.uk/interpro/htt... 💻🧪🆕

Missed our latest webinar about LLM generated summaries for protein classification at InterPro delivered by @matthiasblum.bsky.social? The recording is now available: lnkd.in/ei4fKGXd

Want to use the InterPro API but not sure how to start? Join this upcoming workshop, where @typhainepl.bsky.social will guide you through the fundamentals and practical applications. Discover how to integrate this powerful tool into your workflow! Register now to secure your spot. 💻🧪

Are you going to ISMB/ECCB 2025 @iscb.bsky.social in Liverpool 🇬🇧? Register for our tutorial on 'Genomic Variant Interpretation & prioritisation for clinical research'. More info: tinyurl.com/ahav9djn #genomics #bioinformatics

🆕 New version of InterProScan: 5.73-104.0 3 ways to use it: 1️⃣ Sequence search on the InterPro website: ebi.ac.uk/interpro/sea... 2️⃣ Local installation: interproscan-docs.readthedocs.io/en/v5/Instal... 3️⃣ Local installation using a container: interproscan-docs.readthedocs.io/en/v5/HowToU... 💻🧪

🔈InterPro release 104.0 is live! ✨Update to Pfam 37.2, NCBIfam 17.0, CDD 3.21. ✨661 new entries, including 682 signatures from the Pfam (663), NCBIfam (5), PANTHER (5), CDD (9) databases. Have a look: ebi.ac.uk/interpro/ 💻🧪

New webinar series featuring InterPro, register now!

RT please: Just 1.5 months away from our joint 3DBioinfo/3DSIG amazing conference! These are our two great keynote speakers! @rolanddunbrack.bsky.social & @silviaosuna.bsky.social! Check our preliminary programme here: www.iscb.org/3dbioinfo202... Registration link: www.iscb.org/3dbioinfo202...

🔈InterPro release 104.0 is live! ✨Update to Pfam 37.2, NCBIfam 17.0, CDD 3.21. ✨661 new entries, including 682 signatures from the Pfam (663), NCBIfam (5), PANTHER (5), CDD (9) databases. Have a look: ebi.ac.uk/interpro/ 💻🧪

1/ 🌟At Europe PMC, we are at the heart of open science ♥️🔓 Our mission? To support open science, promote innovation, and connect publications with other research outputs to empower users worldwide. But how do we do it? Let’s break it down 🧵👇

🧬🧪💻 New blog post: Diving deep into the key proteins behind Parkinson's disease. From α-synuclein to LRRK2, we're unravelling the molecular mysteries that could hold the key to treatment breakthroughs. Read more: proteinswebteam.github.io/interpro-blo... #Parkinsons #Neuroscience

🔍 Lost in InterPro data? Our redesigned Help page has you covered! From quick answers to deep dives into protein families, find exactly what you need at www.ebi.ac.uk/interpro/help/ 💻🧪

Prediction confidence scores help #AlphaFold users gauge the reliability of protein structure predictions. 🖥️🧬 But things get more challenging for protein families. A new method helps improve low confidence predictions within protein families. academic.oup.com/bioinformati...

🆕The member database signature pages have undergone a thoughtful reorganisation to improve information accessibility. 1) Curation data are now in Overview 2) HMM information and logo are now in Profile HMM Have a look: www.ebi.ac.uk/interpro/ent...

🆕We've implemented a new “Curation status” filter to help users distinguish between different types of entries (curated vs AI) in the Browse by InterPro and Member DB, have a look: www.ebi.ac.uk/interpro/ent... 💻🧪

2024 was a big year for InterPro! 🎉 🔹 Celebrated InterPro 100 with new features 🤖 Added AI-generated entries 🌟 Improved tools & navigation 📚 Expanded data with new signatures 💬 Joined Bluesky to connect with you! Thank you for your support—here’s to 2025! 🚀 💻🧪

📣 A new version of InterProScan (5.72-103.0) is available. You can download it here: ebi.ac.uk/interpro/abo... More info and documentation: interproscan-docs.readthedocs.io/en/latest/Re... 🧪💻🧬

📝 Just published: Our latest blog walks you through InterPro's major updates - from redesigned protein views to improved data exploration. Read more: proteinswebteam.github.io/interpro-blo...

InterPro release 103.0 is live! 💻🧪 ✨Update to Pfam 37.1 ✨1029 new entries, including 1019 signatures from the Pfam (1008), NCBIfam (2), PIRSF (1), PANTHER (1), CDD (7) databases. Have a look: ebi.ac.uk/interpro/

We’re delighted to have joined BlueSky to engage with the scientific community about protein families, protein domains and related data. Follow us for updates on protein classification, domain characterisation and new features added to the InterPro website.