@brangwynnelab.bsky.social
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A tremendous honor! Thrilled & humbled to receive 2025 Keio Medical Science Prize for launching LLPS
#phaseseparation
field (=
#softmatter
+
#cellbio
) w collaborators esp @HymanLab. & Congrats to Akiko Iwasaki
@virusesimmunity.bsky.social
.
www.princeton.edu/news/2025/09...
#KeioMedicalSciencePrize
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Bioengineer Clifford Brangwynne wins Keio Medical Science Prize
Japanās Keio University awards the prize annually to honor contributions in medicine and life sciences. Brangwynne is being recognized for groundbreaking work that has opened up a new field of cell bi...
https://www.princeton.edu/news/2025/09/19/clifford-brangwynne-wins-keio-medical-science-prize
21 days ago
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reposted by
HHMI
22 days ago
š Congratulations to HHMI Investigators Clifford Brangwynne and Akiko Iwasaki, the two winners of the 30th annual Keio Medical Science Prize. This international prize, awarded by Keio University in Tokyo, honors scientists who have made major contributions to the fields of medical or life sciences.
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these people in my lab are amazing
22 days ago
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Awesome work Anita, congrats on an amazing paper!
add a skeleton here at some point
about 2 months ago
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Check out this awesome story about the work of an awesome (former) undergrad in our lab
@hollycheng.bsky.social
who worked closely w
@zs-biophys.bsky.social
⬠Howard Stone, James Roggeveen & Huan Wang.
bioengineering.princeton.edu/news/2025/st...
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Starting as an undergraduate project, an experiment reveals cellsā secrets
Holly Cheng and her colleagues were the first to successfully use micropipette aspiration to measure parts from a living cell while they were still biologically active
https://bioengineering.princeton.edu/news/2025/starting-undergraduate-project-experiment-reveals-cells%E2%80%99-secrets
about 2 months ago
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Congrats
@yoonjikim.bsky.social
and co-authors!!!!!
add a skeleton here at some point
about 2 months ago
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reposted by
Sarah Cohen
3 months ago
It has been a dream come true to lead a rotation in the
@mblscience.bsky.social
Physiology course - thanks to the amazing Directors
@gladfelterlab.bsky.social
and
@brangwynnelab.bsky.social
, course staff, TAs, and students!
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reposted by
Albert and Mary Lasker Foundation
3 months ago
Combining sequencing and imaging,
@brangwynnelab.bsky.social
maps the spatiotemporal dynamics of rRNA processing, demonstrating how rRNA serves as both a scaffold and a substrate for the nucleolusāa multiphase, liquid-like structure. š§Ŗ š§¬
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Mapping and engineering RNA-driven architecture of the multiphase nucleolus - Nature
Spatially segregatedĀ rRNAĀ processing dictates nucleolar morphology andĀ drivesĀ outward progressionĀ of pre-ribosomal RNAĀ through nucleolar phases.
https://www.nature.com/articles/s41586-025-09207-4
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Congrats to Jing
@jesszhiyuezhao.bsky.social
⬠&
@dnamystrom.bsky.social
⬠on cool manuscript!!! Reveals how cell nucleus is a heterogeneous material, w chromatin organization controlling formation & phase behavior of nuclear condensates.
#CellBiology
#Chromatin
#PhaseSeparation
rdcu.be/evWxR
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Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior
Nature Communications - Chromatin heterogeneity in the cell nucleus modulates the size, mobility, and formation of biomolecular condensates; decreasing chromatin heterogeneity correlates with...
https://rdcu.be/evWxR
3 months ago
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An amazing group of students this year in Brangwynne rotation
@mblscience.bsky.social
Physiology course!!!!
3 months ago
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reposted by
Pombo-GarciaLab
4 months ago
How to spy on condensates: technology feature in
@natmethods.nature.com
Our views on the topic, by Hyman,Rosen,Brangwynne, Sabari, Kappel,Xu & myself, presented here
@hymanlab.bsky.social
@brangwynnelab.bsky.social
@bsabari.bsky.social
@kallikappel.bsky.social
www.nature.com/articles/s41...
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How to spy on condensates - Nature Methods
Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.
https://www.nature.com/articles/s41592-025-02728-w
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reposted by
Max Planck Institute of Molecular Cell Biology and Genetics
4 months ago
How to spy on condensates: technology feature in
@natmethods.nature.com
on self-organization and collective properties of condensates with quotes from Anthony Hyman
@hymanlab.bsky.social
@mpi-cbg.de
,
@brangwynnelab.bsky.social
, and many more.
www.nature.com/articles/s41...
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How to spy on condensates - Nature Methods
Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.
https://www.nature.com/articles/s41592-025-02728-w
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Nice article about the latest in the biomolecular condensate field, with some nice images and quotes from us.
www.nature.com/articles/s41...
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How to spy on condensates - Nature Methods
Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.
https://www.nature.com/articles/s41592-025-02728-w
4 months ago
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The one and only Manu
@prakashlab.bsky.social
inspiring
@mblscience.bsky.social
Physiology students at this morning's lecture.
4 months ago
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A great morning with the
@mblscience.bsky.social
Physiology students after my talk today.
4 months ago
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Awesome paper alert! Learn about spectrum of chromatin condensate morphologies due to elastocapillary effects (no, liquids do not need to be spherical!), from amazing duo
@dnamystrom.bsky.social
& Hongbo Zhao, w/ important contributions from co-authors Jorine Eeftens, Mikko Haataja, Andrej Kosmrlj.
add a skeleton here at some point
4 months ago
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Princeton's new Omenn-Darling Bioengineering Institute is hiring! New building opening this Fall, & Princeton is an awesome place to live & do amazing research at intersection of engineering & life sciences. **Please spread the word***
bioengineering.princeton.edu/join/open
.
4 months ago
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Start of 2025
@mblscience.bsky.social
Physiology course! This is the second year of Amy
@gladfelterlab.bsky.social
and I co-Directing this absolutely amazing and life-changing course:
www.mbl.edu/education/ad...
4 months ago
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Such a wonderful symposium at UMichigan! And a fantastic opportunity to connect with our beloved benefactors (and Michiganders) Gil Omenn and Martha Darling, together with my Princeton/Omenn-Darling Bioengineering Institute colleague (& Deputy Director)
@toettch.bsky.social
add a skeleton here at some point
4 months ago
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reposted by
Zheng Shi
5 months ago
Very glad to contribute to this cool study of of nucleoli, led by former Princeton undergrad Holly Cheng! P.S., we all looked much younger when we were working on this project (see picture below) š
add a skeleton here at some point
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Congrats to this year's Brangwynne lab new PhD Kevin Xu (co-advised with Avalos) and graduating undergrads Aya Abu-Alfa and Emmett Grover. Kevin is now CEO of a startup, Aya is off to MD/PhD program, and Emmett to medical school. Congratulations - we are so proud of you!!!!
5 months ago
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Nucleoli as biomolecular bubble tea! Congrats to former Princeton ugrad Holly Cheng (now GS @MIT) ->Holly's senior thesis work, a close collab w Roggeveen Wang &
@zs-biophys.bsky.social
⬠&Stone. Come for the cool movies & stay for the viscoelasticity!
www.pnas.org/doi/10.1073/pnas.2407423122
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5 months ago
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reposted by
U-M Life Sciences Institute
5 months ago
The 2025 Saltiel Life Sciences Symposium is this Thursday (5/29)!
@brangwynnelab.bsky.social
will start us off with the Mary Sue and Kenneth Coleman Lecture at 9:00 AM, followed by talks from
@jamesknunez.bsky.social
at 9:55 and
@leonardomorsut.bsky.social
at 10:25.
myumi.ch/lsi-symposiu...
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So grateful for our amazing inaugural advisory council for the Omenn-Darling Bioengineering Institute, who came to Princeton last week to learn about and help guide all that is happening in ODBI, the future of Bioengineering at Princeton. Thank you all!!!
bioengineering.princeton.edu
5 months ago
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What drives cytoplasmic mRNA organization? We created unbiased, genome-wide maps of mesoscale RNA-RNA spatial proximity, revealing impact of encoded protein function. Fantastic work from
@lindsayabecker.bsky.social
@sofiquinodoz.bsky.social
@davidaknowles.bsky.social
www.biorxiv.org/content/10.1...
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Genome-wide mapping of mesoscale neuronal RNA organization and condensation
Subcellular RNA organization can affect critical cellular functions. However, our understanding of RNA microenvironments, particularly biomolecular condensates, remains limited, largely due to a lack ...
https://www.biorxiv.org/content/10.1101/2025.04.19.649570v1
6 months ago
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Lovely dinner tonight with Nathan Vardi, author of the page-turner "For Blood and Money: Billionaires, Biotech, and the Quest for a Blockbuster Drug". Nathan will speak to Princeton students in our Biotech class tomorrow, can't wait!
6 months ago
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Cool work from some amazing Princeton colleagues!
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7 months ago
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Princeton's Omenn-Darling Bioengineering Institute is looking for a Cell Engineering facility Director. A tremendous opportunity to join our growing community, in brand-new building & brand new Institute! Please spread the word!!!
bioengineering.princeton.edu
.
puwebp.princeton.edu/AcadHire/app...
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Omenn-Darling Bioengineering Institute
https://bioengineering.princeton.edu/
7 months ago
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Excited about Nereid's progress in using our Corelet technology to find new drugs: Corelet⢠Platform: Precision High Throughput Screening for Targeted Dr...
sciencedirect.com/science/arti...
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Corelet⢠Platform: Precision High Throughput Screening for Targeted Drug Discovery of Biomolecular Condensates
Biomolecular condensates (BMCs) are crucial for cellular organization and function, and their dysregulation is linked to neurological, oncologic and iā¦
https://sciencedirect.com/science/article/pii/S2472555225000176
7 months ago
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ā⦠without scientific progress no amount of achievement in other directions can insure our health, prosperity, and security as a nation in the modern world." - written half a century ago, by Vannevar Bush, more relevant today than ever. see this piece by Princeton's Tilghman:
doi.org/10.1091/mbc....
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It's All about the Talent | Molecular Biology of the Cell
https://doi.org/10.1091/mbc.e10-05-0472
8 months ago
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So thrilled to have our new colleague Tina Kim join us (back!) at Princeton as joint Bioengineering (ODBI) and Neuroscience (PNI) hire:
bioengineering.princeton.edu/news/2025/ch...
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Christina Kim ā11 joins PNI and Bioengineering to build new molecular tools for healing the brain
Her research focuses on engineering new molecular tools to replicate the therapeutic benefits of certain drugs, such as psychedelics to relieve anxiety, while minimizing unwanted effects like hallucin...
https://bioengineering.princeton.edu/news/2025/christina-kim-%E2%80%9911-joins-pni-and-bioengineering-build-new-molecular-tools-healing-brain
8 months ago
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Attention all you fantastic and energetic student and postdocs!!!!!
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9 months ago
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Excited to see this (cover) article on condensates come out in Scientific American. Nice quotes from me and many folks in the field.
www.scientificamerican.com/article/myst...
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Mysterious Blobs in Cells Are Changing the Way We Understand Life
Tiny specks called biomolecular condensates are leading to a new understanding of the cell
https://www.scientificamerican.com/article/mysterious-blobs-found-in-cells-are-rewriting-how-life-works/
9 months ago
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9 months ago
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Hello World!
10 months ago
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you reached the end!!
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