I’m reading abstracts for ABRCMS and seeing over and over again where students comment about what a transformative experience ABRCMS was for their peers and mentors. We cannot let this conference disappear because what we will lose will be tremendous. Funders, I hope you are listening.

Such a delight to share our work on the evolution of a cheese rind fungus in @currentbiology.bsky.social. This is the fantastic PhD work of @nicolasleonlouw.bsky.social and resulted from amazing collaborations, a wedding proposal(!), an undergrad course, & more! 🧵 www.cell.com/current-biol...

What was antibiotic resistance like before we ever used antibiotics? How did we change what antibiotic resistance genes looked like over 100 years? Our paper looking at resistance genes from a century of NCTC historical isolates now out in mGen: www.microbiologyresearch.org/content/jour...

Join me in donating to ABRCMS. For many of us early in our careers (and for many of us now), this is THE conference. Let’s make sure future generations get the same experience. I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾

Check out the Ziemert Lab’s new YouTube channel m.youtube.com/@ZiemertLab We’ve uploaded short tutorial videos on how to use our tools for genome mining and natural product discovery. Thanks Semih, @martinaadamek.bsky.social @turgutmesut.bsky.social ! #GenomeMining #SecMet #naturalproducts

"Philly, we're listening! Share your ideas with the Free Library. We are reimagining the future of public libraries in our city, and we want to hear from you." Library townhalls in Philly. You should all go [SERIOUSLY]: libwww.freelibrary.org/about/strate...

1/"I have a presentation tomorrow." If you've ever collaborated with wet lab scientists as a bioinformatician… you’ve heard this. And died inside a little.

I appreciate the offers from other scientists to help Harvard (students, labs, etc) through this attack, but what would be most helpful is for you to use your position to contact your elected representatives and make it clear this fight isn't just Harvard, it will affect you, and their districts too

I am thrilled to share after years of work/procrastination that the MassQL manuscript is finally published in @natmethods.nature.com - "A universal language for finding mass spectrometry data patterns". This was an team effort from all co-authors that helped shape MassQL and how it could be used.

Recently, we found out that our R01 funded through PAR-22-241 was withdrawn by NIAID as the NIH no longer prioritizes research programs related to DEI. This has been devastating news for our young research group, and we are now trying to scram together for a path forward 🧵1/12

What excitement, instead of one book I got five. Excited to explore the science behind Victorian mauve with my students this semester.

Preprint alert!! 🎉 Ever struggle to activate a carrier protein? Led by Kenneth Hsu (Haverford '25), the Charkoudian Lab unearthed a novel PPTase from Dictyobacter vulcani 🌋 with remarkable promiscuity (in our case, better than Sfp & AcpS)! Grateful to be an alum of this phenomenal research team 💗

A whopping 26 study sections are not meeting today: AI, BDE, BTEN, CMAD, CMBG, CPSS, DHMI, EDIT, GVE, HBPP, IHD, ISD, MAI, MCTC, MFSR, NMBH, NPAS, ODCS, ODHS, PN, SMN, SSPB, THI, VID, ZRG1 F02A D 20, ZRG1 MCST U 55*

🚨 new preprint 🚨 Here we report that deleting the Septin aspB results in cidal activity of the static anti cell wall drug Caspofungin. This wasn’t only in vitro as 🐭 infected with the mutant and treated had 70% survival compared to 30% of the wild-type 1/2

For #BlackHistoryMonth pharmaceutical #chemist Alice Ball (1892-1916) who developed 1st effective treatment for leprosy. 🧪🐡👩🏾‍🔬 #histsci Though her life was cut tragically short, her research saved 1000s from exile & painful, ineffective lifelong treatment for leprosy, & she was a trailblazer for 🧵

Chemical inhibition of a bacterial immune system https://www.biorxiv.org/content/10.1101/2025.02.20.638879v1

Super stoked to share this pre-print covering our work on some sulfotransferase enzymes with surprising stereoselectivity! doi.org/10.26434/che...

Super stoked to share this pre-print covering our work on some sulfotransferase enzymes with surprising stereoselectivity! doi.org/10.26434/che...

Has the ACS put out a statement or done anything (apart from great reporting in C&EN) in response to the current state of *gestures at everything*? Really questioning what my membership dues are going towards if they won't play ball here, given the huge implications for chemists nationwide.

Here are the papers covering those tools. Classical MN www.pnas.org/doi/10.1073/... FBMN www.nature.com/articles/s41... IIMN www.nature.com/articles/s41... FBMN-stats chemrxiv.org/engage/chemr... gnps dashboard www.nature.com/articles/s41... modifinder pubs.acs.org/doi/10.1021/... 3/4

Happy New Year 🎉 Our collab with Strittmatter lab TU Munich shows the power of #massspec to see #bacteria in #tissues 233 bacterial species were mined for markers at different phylogenetic levels. Watch out for those taxon-specifc markers (TSMs) in your #spatialmetabolomics tinyurl.com/yza6t32w

Interesting biorxiv from Megan Matthews lab on Hydralazine inhibiting cysteamine dioxygenase to treat preeclampsia and senesce glioblastoma. www.biorxiv.org/content/10.1...

Come be my colleague! We’re hiring an assistant professor in marine natural products and marine biotechnology at SIO - check out this link to learn more: apol-recruit.ucsd.edu/JPF04101

Can finally confirm: #ABRCMS in person definitely beats the online early-pandemic versions. I didn't have to travel and I'm still wiped out by so many hours of posters... but there was so much exciting science and so many talented undergrad and postbac researchers! Highly recommended. #ABRCMS2024

If you’re interested in microbial specialized metabolites #naturalproducts - we’ve compiled a list of useful bioinformatics / community resources - it’s not meant to be comprehensive- just somewhere to start - let us know if you find it useful 😊 #microsky #secmet

Our preprint of the BGC atlas is online. A map of secondary metabolite gene clusters in the environment. A community tool and collaboration of our lab with @tilmweber.bsky.social @marnixmedema.bsky.social @danudwary.secondarymetabolism.com and more: biorxiv.org/cgi/content/...

Now (again) soliciting community feedback on "Running a queer- and trans-inclusive faculty hiring process" Now with a much broader scope across the biological sciences (and neighbors). We value your input! Article: ecoevorxiv.org/repository/v... Feedback form: forms.gle/dj4iNiy4boZ6...

I am developing a new experiment for my advanced organic lab course to teach students column chromatography in a colorful fashion. I would like to be able to publish the experiment, but my class is very small, and publication would likely benefit from piloting with more students.

Hello BlueScience Crowd! 🧪 A few dates of the MBL's 2024 Advanced Research Training Courses (ARTCs) have changed since we first posted the schedule. Please make sure you check mbl.edu/courses for the most up-to-date course info!

The 2024 Chemistry Faculty Jobs List (by Andrew Spaeth, me) has 365 tenure-track positions and 30 teaching positions: bit.ly/facultychemjobs2024 facultychemjobs chemjobs chemsky 🧪⚗️