An article I wrote about this topic a few years ago: worksinprogress.co/issue/real-p...

The DNA of pure DCIS. We look at prognosis (invasive & in situ local recurrence) & benefit to radiotherapy in a unique cohort of Ontarians. A manuscript with my long term collaborators Eileen Rakovitch (Sunnybrook) & @vdumeaux.bsky.social breast-cancer-research.biomedcentral.com/articles/10....

The Oilers did extremely well to keep it as close as they did against a far better team.

I have to say, I might have had difficult stopping McDavid even in my prime goaltending days.

Is it my imagination or is @wired.com the only news source from the USA now willing to report on the regime? I hope they keep it up.

10 courses to get you started with bioinformatics 🧵 Bookmark! 1/ rafalab.dfci.harvard.edu/pages/harva... by the almighty Rafa

Does the ICD-11 offer a diagnosis for a type of severe recurrent - but entirely foreseeable - post-traumatic stress disorder with onset at this time of every year? Asking for a friend here in southern Ontario.

When I become rich, I will create my own hockey channel where commentators are forced to provide inferential statistics (CI, p-value, ACC, *anything*) for each proposed prognostic indicator. There will be clinical trials: random forced shavings, etc ... HNIC et al. have given stats a bad name.

🇨🇦 🏳️‍🌈 🤖📈🧬💻 🏳️‍⚧️ 🇨🇦 Tomorrow - Thursday April 17th 1pm - Open house for students with backgrounds in math, stats and computation to explore graduate work in the life & biomedical sciences @ Western University (Canada). Zoom or in person. western-bioinfo.github.io/events/open-... @westernu.bsky.social

🇨🇦 🏳️‍🌈 🤖📈🧬💻 🏳️‍⚧️ 🇨🇦 Do you have a background in math, stats or computation & considering grad studies in the life science & biomedicine? Western University will hold an Open House with talks from researchers who use/develop quantitative methods in their research. western-bioinfo.github.io/events/open-...

I wish Canada would do the same.

Another nice collaboration with Sunnybrook and @vdumeaux.bsky.social

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...

Our new manuscript covering a new FFPE-based RNA-seq methodology. Led by John Mucaki and with our collaborators Vanessa Dumeaux at Western and Eileen Rakovitch at Sunnybrook. www.biorxiv.org/content/10.1...

Vote Ford Out

I even like Marchand.

It never ceases to amaze me how researchers are still making breakthroughs with AIMS, a method we published 10 years ago with @hallettmiket.bsky.social . Now, AIMS is proving instrumental in revealing BC subtype switching before and after neoadjuvant treatment. tinyurl.com/bdday25t

The Department of Pathology and Laboratory Medicine at the Schulich School of Medicine & Dentistry, Western University, is seeking applications for a full-time, tenure-track faculty position in Cancer Immunology and Therapeutics. PLEASE REPOST ! www.nature.com/naturecareer...

So the meth head that lives in the apartment below me just told me that he wouldn't break into my apartment if I could show that I was more serious about controlling the flow of meth into the building. It's best in these kinds of interactions to just nod your head yes and quietly walk away.

Ok so Canada needs an endogenous car company. My vote is to resurrect the Manic GT, retrofit it as an EV, throw some snow tires on and we're good to go. www.youtube.com/watch?v=YRUN...

📢 Excited to share our latest work, now on bioRxiv! We've used deep learning to uncover functional archetypes in the adult human gut #microbiome, shedding light on interindividual variability microbiome stability, and disease associations: www.biorxiv.org/content/10.1... #AI #microbiology 🧵 1/n

Good.

I so believe this.

If the coming Zombie Apocalypse has a fungal origin, I am pretty certain ground zero is some teenager's hockey bag.

I teach a class on data science here at Illinois and during the seminar I host a competition for the class called "The Hunt for the Worst Data Visualization." This was my most popular post on Xitter, so reproducing some of the best submissions from previous years here:

I have created wwater.ca to provide graphs of #COVID19, RSV, and flu levels in regions across #Canada using the Government of Canada's #wastewater initiative data. Inspired by the Ontario government shutting down the crucial Wastewater Surveillance Initiative on July 31, 2024.

Fun collaboration with Nikki Case and colleagues; my contribution was to extend our Candescence software for host-pathogen interactions.🧬🖥️ journals.asm.org/doi/full/10....

Excited to share our latest publication in @elife.bsky.social! Introducing a refined single-cell transcriptomics technique applied to thousands of C. albicans cells, shedding light on drug tolerance mechanisms for more effective antifungal treatments @hallettmiket.bsky.social doi.org/10.7554/eLif...

🧬 🖥️ What are your best resources for the history of machine learning? Books? papers? interpretative dance? that describes the main mathematical/algorithmic trends since the 50s?

🧬 🖥️ 🧪 That fresh server smell 🤍. The promise of vast empty fields of storage ⛰️ 🌼. The pristine structure of a freshly installed, yet-to-be-mutilated operating system 🧽 🛁.

Lior Pachter's Caltech Computational Biology course. github.com/pachterlab/B...