Carsten Sachse
@sachsegroup.bsky.social
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📥 232
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The Sachse group @fz_juelich:
#cryoEM
#cryoET
#CLEM
#FIBSEM
#autophagy
.
reposted by
Carsten Sachse
Tanmay Bharat
5 months ago
Finally in peer-reviewed form: Mapping the ultrastructural topology of the corynebacterial cell surface.
@bupbuse.bsky.social
@vikramalva.bsky.social
Please also see concurrent beautiful work from
@adriasogues.bsky.social
and Han Remaut.
add a skeleton here at some point
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Carsten Sachse
Josh Dickerson
5 months ago
After years parked at a Polara, I’m excited to share that my PhD work is finally out! We figured out why imaging at liquid helium temperatures wasn’t working—and how to fix it. 🔗
www.pnas.org/doi/10.1073/...
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Reducing the effects of radiation damage in cryo-EM using liquid helium temperatures | PNAS
The physical limit in determining the atomic structure of biological molecules is radiation damage. In electron cryomicroscopy, there have been num...
https://www.pnas.org/doi/10.1073/pnas.2421538122
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Philipp's manuscript on our CryoVIA toolkit
www.sciencedirect.com/science/arti...
is out! For those interested in studying protein lipid interactions and high-throughput analysis of membrane structures (sizes, shapes, curvature etc.) - this could be your tool (
github.com/philipp-scho...
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CryoVIA: An image analysis toolkit for the quantification of membrane structures from cryo-EM micrographs
Imaging of lipid structures and associated protein complexes using cryoelectron microscopy (cryo-EM) is a common visualization and structure determina…
https://www.sciencedirect.com/science/article/pii/S0969212625000139?via%3Dihub
8 months ago
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Our first post on blue: grad student Philipp's software: for those interested in looking at membrane reconstitution by cryo-EM. Automated analysis of lipid fine structure and membrane shape classifications:
biorxiv.org/cgi/content/...
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CryoVIA - An image analysis toolkit for the quantification of membrane structures from cryo-EM micrographs
Imaging of lipid structures and associated protein complexes using electron cryo-microscopy (cryo-EM) is a common visualization and structure determination technique. The quantitative analysis of the ...
https://biorxiv.org/cgi/content/short/2025.01.09.632183v1
9 months ago
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Carsten Sachse
Irene Vercellino
9 months ago
Excited to share that I have been elected as member of the "Junge Kolleg" of the Nordrhein-Westfalian Academy of Sciences and Arts. I am honoured to have this opportunity to serve the community! Here's the link to the announcement, unfortunately only in German
www.awk.nrw/news/nachwuc...
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Nachwuchsförderung: Nordrhein-Westfälische Akademie nimmt neun neue Stipendiatinnen und Stipendiaten in ihr Junges Kolleg auf
Zum 1. Januar 2025 begrüßt die Nordrhein-Westfälische Akademie der Wissenschaften und der Künste neun weitere herausragende Talente in ihrem Jungen Kolleg. Sie haben die Jury in einem mehrstufigen Aus...
https://www.awk.nrw/news/nachwuchsfoerderung-nordrhein-westfaelische-akademie-nimmt-neun-neue-stipendiatinnen-und-stipendiaten-in-ihr-junges-kolleg-auf
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