Carsten Sachse
@sachsegroup.bsky.social
📤 486
📥 256
📝 5
The Sachse group @fz_juelich:
#cryoEM
#cryoET
#CLEM
#FIBSEM
#autophagy
.
We are looking for a team leader to join the cryo-EM facility work at the new Ernst Ruska-Centre 2.0 at the Forschungszentrum JĂĽlich. We have a series of microscopes used by (
@irene-vercellino.bsky.social
, Schröder,
@sachsegroup.bsky.social
) and external users.
www.fz-juelich.de/de/karriere/...
loading . . .
Team Leader – Life Science Cryo-Electron Microscopy (Cryo-EM) Facility
Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C) at Forschungszentrum JĂĽlich houses some of the world`s most advanced electron microscopes and tools for nanocharacterisation. U...
https://www.fz-juelich.de/de/karriere/stellenangebote/2025-353?etcc_cmp=Stellenposts&etcc_med=email&et_cmp_seg2=Recruiting
9 days ago
0
16
14
Really happy to see the work (
doi.org/10.1038/s414...
) published. Here, we show the full-length helical cryo-EM structure of p62/SQSTM1 and first cryo-ET visual of p62 positive structures inside the cell.
loading . . .
Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo - Nature Communications
The selective autophagy receptor p62/SQSTM1 is organized in a structured double helical filament in vitro, the cryo-electron tomographic images in ATG5 knockdown conditions reveal Ca-rich layers of p6...
https://doi.org/10.1038/s41467-025-66785-7
27 days ago
1
23
9
reposted by
Carsten Sachse
Irene Vercellino
about 2 months ago
Grateful to have received the Wilhelm und Else Heraeus-Stiftung Research Fellowship, to support my group’s work at the Ernst Ruska-Centre (ER-C) of Forschungszentrum Jülich
#cryoem
1
7
2
reposted by
Carsten Sachse
Tanmay Bharat
8 months ago
Finally in peer-reviewed form: Mapping the ultrastructural topology of the corynebacterial cell surface.
@bupbuse.bsky.social
@vikramalva.bsky.social
Please also see concurrent beautiful work from
@adriasogues.bsky.social
and Han Remaut.
add a skeleton here at some point
4
72
31
reposted by
Carsten Sachse
Josh Dickerson
8 months ago
After years parked at a Polara, I’m excited to share that my PhD work is finally out! We figured out why imaging at liquid helium temperatures wasn’t working—and how to fix it. 🔗
www.pnas.org/doi/10.1073/...
loading . . .
Reducing the effects of radiation damage in cryo-EM using liquid helium temperatures | PNAS
The physical limit in determining the atomic structure of biological molecules is radiation damage. In electron cryomicroscopy, there have been num...
https://www.pnas.org/doi/10.1073/pnas.2421538122
2
66
23
Philipp's manuscript on our CryoVIA toolkit
www.sciencedirect.com/science/arti...
is out! For those interested in studying protein lipid interactions and high-throughput analysis of membrane structures (sizes, shapes, curvature etc.) - this could be your tool (
github.com/philipp-scho...
).
loading . . .
CryoVIA: An image analysis toolkit for the quantification of membrane structures from cryo-EM micrographs
Imaging of lipid structures and associated protein complexes using cryoelectron microscopy (cryo-EM) is a common visualization and structure determina…
https://www.sciencedirect.com/science/article/pii/S0969212625000139?via%3Dihub
11 months ago
0
7
5
Our first post on blue: grad student Philipp's software: for those interested in looking at membrane reconstitution by cryo-EM. Automated analysis of lipid fine structure and membrane shape classifications:
biorxiv.org/cgi/content/...
loading . . .
CryoVIA - An image analysis toolkit for the quantification of membrane structures from cryo-EM micrographs
Imaging of lipid structures and associated protein complexes using electron cryo-microscopy (cryo-EM) is a common visualization and structure determination technique. The quantitative analysis of the ...
https://biorxiv.org/cgi/content/short/2025.01.09.632183v1
12 months ago
0
9
0
reposted by
Carsten Sachse
Irene Vercellino
about 1 year ago
Excited to share that I have been elected as member of the "Junge Kolleg" of the Nordrhein-Westfalian Academy of Sciences and Arts. I am honoured to have this opportunity to serve the community! Here's the link to the announcement, unfortunately only in German
www.awk.nrw/news/nachwuc...
loading . . .
Nachwuchsförderung: Nordrhein-Westfälische Akademie nimmt neun neue Stipendiatinnen und Stipendiaten in ihr Junges Kolleg auf
Zum 1. Januar 2025 begrüßt die Nordrhein-Westfälische Akademie der Wissenschaften und der Künste neun weitere herausragende Talente in ihrem Jungen Kolleg. Sie haben die Jury in einem mehrstufigen Aus...
https://www.awk.nrw/news/nachwuchsfoerderung-nordrhein-westfaelische-akademie-nimmt-neun-neue-stipendiatinnen-und-stipendiaten-in-ihr-junges-kolleg-auf
0
9
2
you reached the end!!
feeds!
log in