Happy to see this work on IG light chains from @e-engelbrecht1.bsky.social in press www.nature.com/articles/s41... How else will germline variation impact the expressed repertoire? Can't wait to see! Thanks to awesome collabs: @williamlees.bsky.social @guryaari.bsky.social @ayeletperes.bsky.social

The AIRR-ML-2025 challenge is LIVE on @Kaggle, but the real question is… are you up for it? We’re challenging the best in #MachineLearning & #DataScience to decode the immune system. Think you have the skills? Prove it. 💰 $10,000 prize pool 📄 Co-author a @NatureMethods paper

🧬 VDJbase and OGRDB: 3000+ IG/TR samples across human and rhesus macaque with curated AIRR-seq and long-read genomic data. LET'S CHANGE THE WAY WE UTILIZE IG/TR GENOMIC AND REPERTOIRE DATA! @guryaari.bsky.social @williamlees.bsky.social @ayeletperes.bsky.social academic.oup.com/nar/advance-...

Happy to announce the publication of our work exploring under-appreciated genetic diversity in the human IGHC region. Awesome work by @uddalok.bsky.social. So grateful for our amazing co-authors. @williamlees.bsky.social @guryaari.bsky.social @ayeletperes.bsky.social www.cell.com/cell-genomic...

Check it out! Highly recommended for anyone passionate about ML/AI or computational biology and immunoogy.

Hi. If you're interested in learning more about the state of play in IG and T cell receptor gene curation, check out these articles: www.sciencedirect.com/science/arti... @jamieheather.bsky.social @guryaari.bsky.social @williamlees.bsky.social @ayeletperes.bsky.social @elisarosix.bsky.social

🚨 Publication Alert! AlignAIR is live, a deep learning–powered tool for aligning BCR/TCR sequences: 👉 alignair.ai Explore the paper for results and methodological details: 📄 lnkd.in/dKY5fPZz It’s been a long, creative, and rewarding journey with an amazing team. We’d love to hear your feedback!

Turns out...just like in the antibody heavy chain repertoire, germline variants in the immunoglobulin lambda and kappa loci influence the composition of light chain B cell receptors! Way to go Eric @e-engelbrecht1.bsky.social !!!! www.biorxiv.org/content/10.1...

A truly enjoyable and collaborative effort—this is what science should be all about!

Did you know that human immunoglobulin constant genes are crazy diverse? It's got me thinking...Proud of Uddalok Jana! And grateful for collabs @guryaari.bsky.social @williamlees.bsky.social @ayeletperes.bsky.social @e-engelbrecht1.bsky.social @yscientist.bsky.social www.biorxiv.org/content/10.1...

Looking forward to hearing from the great speakers lined up for the “2025 Immcantation Users Group Meeting!” Check out the program and register for this free virtual meeting 1/30/25 10AM-1:40PM (ET) at: immcantation.github.io/users-meetin... @immcantation.bsky.social

Check out long-read sequencing results in human IGH! HUGE duplications in constant gene regions...and 7 copies of IGHV3-23 on one haplotype! @lossiusandreas.bsky.social @williamlees.bsky.social www.biorxiv.org/content/10.1...

Check out our new publication: An unbiased comparison of immunoglobulin sequence aligners. academic.oup.com/bib/article/...