📖 Must-read: AMR in Humanitarian Settings AMR is a global health threat, yet evidence from fragile contexts is scarce. MSF’s review highlights research priorities for the most vulnerable: ✅ IPC ✅ AMS ✅ Diagnostics & Surveillance journals.plos.org/globalpublic...

As cholera outbreaks surge and global vaccine supplies remain strained, WHO prequalified Euvichol-S in 2024 to meet demand faster. ➡️ For the first time, a study assesses its real-world effectiveness in a one-dose regimen during an epidemic in South Sudan. epicentre.msf.org/en/news/euvi...

How can HIV prevention be made more accessible to the populations most at risk? In Malawi, Epicentre and MSF are conducting a study to document the introduction of CAB-LA among sex workers, a group particularly at risk of HIV infection. #VIH #PrEP epicentre.msf.org/en/news/anal...

On recrute un.e responsable des activités épidémiologiques pour la mission Tchad de MSF France. Vous avez un diplôme en épidémiologie ou en santé publique, postulez ci-dessous 👇🏾 smrtr.io/vWCQ3

Lung ultrasound (LUS) shows promise in TB diagnosis ➡️High sensitivity, comparable to chest X-ray, but lower specificity ✅Valuable where radiography is unavailable ✅a new scoring system developed improves accuracy, but further validation is needed www.sciencedirect.com/science/arti...

🌍#WorldAMRWeek Replay our Scientific Day session on Diagnostics for Antibiotic Stewardship: ✔ Avoid inappropriate STI treatments ✔ Why cumulative antibiograms matter ✔ Rapid tests for carbapenemase-producing bacteria in MSF labs 🎥 Watch now: youtu.be/FlwmAVONDuo

How can we better protect children from malaria in highly seasonal regions? Epicentre is pleased to be part of the Imvacs Project testing an integrated approach: combining the R21/Matrix-M vaccine with Seasonal Malaria Chemoprevention for children in Mali & Burkina Faso. youtu.be/r2v9EvWQ1JE?...

Just announced at #WCLH2025: WHO treatment decision algorithms could nearly double pediatric TB diagnoses and treatments. This breakthrough could save thousands of lives—urgent adoption is needed. epicentre.msf.org/en/news/who-...

Our study in BMJ Global Health assessed three prenatal nutrition strategies in rural Niger to improve maternal health and reduce adverse pregnancy outcomes. Findings: no significant differences between approacheshttps://gh.bmj.com/content/10/11/e021013

On November 13 at 3 p.m. CET, join writer and advocate for the fight against tuberculosis @johngreensbluesky.bsky.social for a live YouTube roundtable co-hosted by MSF on improving care for children with TB—nearly half of 1.2M cases in 2024 went undiagnosed. #EndTB www.youtube.com/watch?v=XBqQ...

Maths in action for malaria prevention @astmh.bsky.social ! 🦟 A mathematical model, using routine surveillance & climate data, helped define the optimal strategy for seasonal malaria chemoprevention in southern Chad @swisstph.ch #TropMed25

New randomized, controlled trial results @astmh.bsky.social show longer intervals (6 & 12-month) between Euvichol-Plus® may be considered an alternative to the recommended 14-day regimen in adults and children. A promising option amid vaccine shortages and delayed 2nd doses. #TropMed25 #6469

Come see us at @astmh.bsky.social from November 9 to 13. Find us at BOOTH #215, where we’ll be joining forces with MSF and @dndi.org And don’t miss posters and oral presentation which will feature some of our work. #6469 #6169 #6981 #7782 #TropMed25 #ASTMH2025

Doubling rifampicin dosing helps more patients reach therapeutic levels in HIV–TB coinfection. EFV-based ART slightly - but not significantly - affects rifampicin & isoniazid PK. ➡️ Safety & efficacy of the combined regimen academic.oup.com/jac/advance-...

In Mali, an ancillary study compares two R21/Matrix-M vaccine formulation —10-dose vs. 2-dose—to simplify logistics, as part of the broader #IMVACS project which aims to evaluate the effectiveness of a new integrated strategy for administering this vaccine. www.imvacs.org/safli-r21-10/

📹 Modeling to guide humanitarian action Hugo Soubrier explains how modeling can help MSF make faster and more informed decisions during epidemics such as Ebola in the DRC and hepatitis E in South Sudan. #HumanitarianAid #Epidemiology #Modeling #MSF youtu.be/Wfqo8oOYi6U?...

A promising cervical screening strategy for low-resource settings combining: ✅ HPV testing ✅ automated cervical visual evaluation … to accurately identify women most at risk of precancer (CIN3+). Data from 9 countries confirm strong predictive power. academic.oup.com/jnci/article...

In KwaZulu Natal, South Africa, over 10% remain at risk of transmitting HIV — often unaware of their status or without viral suppression. Prevention, tailored care & access to injectable PrEP are key. ⚠️ But PEPFAR funding cuts threaten progress. epicentre.msf.org/en/news/hiv-...

One step further in decentralizing care for SAM First large RCT shows caregiver training boosts knowledge & confidence in at-home monitoring of children with uncomplicated SAM in community-based treatment. gh.bmj.com/content/10/1...

Sharing findings from the GastroSAM study, which compared intravenous and oral rehydration in children with severe acute malnutrition. The Niger site was supervised by our center, in collaboration with MSF Switzerland, contributing directly to this important research.👇

Au Mali, 77% des femmes atteintes d’un cancer du sein sont diagnostiquées à un stade avancé. Et pourtant, une étude menée par Epicentre montre que l’approche multidisciplinaire de MSF a permis d’atteindre 72% de survie à 3 ans contre 12,7% en 2015. #OctobreRose youtu.be/81o5tL4BcuY?...

A new meta-analysis shows that, ten years after its introduction in the Sahel, seasonal malaria chemoprevention (SMC) reduces the incidence of malaria in children under 5.🔽

Hypertension affects 1 in 5 people in parts of Kenya. Despite efforts to decentralize care and introduce single-pill treatments, access remains limited—especially in remote rural areas. Social sciences help tailor care to local realities.👇 epicentre.msf.org/en/news/beyo...

Les médecins ne peuvent pas arrêter un génocide. Nos dirigeants, OUI ! #MSF demande à la #France d’utiliser tous les leviers politiques, diplomatiques et économiques dont elle dispose afin d’obtenir d’ #Israël :

Using surveillance data from MSF’s Bentiu vaccine study, we evaluated the performance of the tests. The Assure RDT showed good sensitivity (86%), outperforming PCR and specificity comparable to ELISA (94.7%). ✅ Supports its use in Hep E surveillance academic.oup.com/jid/advance-...

🎗️Childhood Cancer Month In Uganda, ~3,000 children develop cancer each year — but only 1,000 are diagnosed, often at advanced stages. Poor access to care, low awareness & social barriers make early diagnosis a challenge. In Mbarara, we’re leading 2 studies to change that⬇️

Lessons from the measles outbreak in Kismayo, Somalia (2020–2021): 🔹 Attack Rates: 12% in children <5, 17% among IDP children 🔹 Case Fatality Ratios: 5.9% in children <5, 11.5% among IDP children ➡️ Urgent need to:⬇️

A new retrospective cohort study from the MSF Trauma Centre in Aden, Yemen, analysed 177 patients undergoing internal fixation (IF) procedures to address the high burden of fractures Key findings on 208 fractures treated in 2022:⬇️

MSF designed the Mini-Lab, an all-in-one microbiology lab for remote areas and use by non-expert staff. Key findings of its assessment at a District Hospital in Central African Republic: ⬇️

Les autorités sanitaires du Tchad et MSF intègrent le vaccin R21 à la prévention saisonnière du paludisme à Moïssala. Cette campagne innovante permet à Epicentre de comparer deux stratégies (CPS vs PEV) pour mieux protéger les enfants <5 ans en zones à forte transmission. youtube.com/shorts/tZgoa...

We're recruiting a Study Coordinator for the project INTEGRATE—a multinational, multi-centre clinical trial platform aiming to evaluate new therapeutic options for Lassa fever. 📍 Location: Bauchi, Nigeria To apply, click here 👉https://smrtr.io/sXXGH

A study in Uganda and Zambia evaluated 3 centrifuge-free stool methods for paediatric TB diagnosis using Xpert MTB/RIF Ultra. Results support WHO’s endorsement of stool-based testing, highlighting its simplicity and potential to improve access in LMICs. www.thelancet.com/journals/lan...

Multi-resistant bacteria identified in malnourished children in Niger A study by the Ineos Oxford Institute in collaboration with Epicentre reveals @natcomms.nature.com the rapid spread of antibiotic-resistant bacteria in a hospital in the Madarounfa district. epicentre.msf.org/en/news/mult...

Epicentre is recruiting an epidemiologist! Want to participate in observational studies, population surveys (mortality, nutrition, seroprevalence), or cohort studies, in support of MSF operations... 👉 apply smrtr.io/sKshD

RDC – Nord-Kivu En 2024, près de 40 000 femmes ont été prises en charge par MSF pour des violences sexuelles — un chiffre sans précédent. Depuis janvier 2025, pas d’amélioration et les autres formes de violence explosent aussi, selon notre enquête epicentre.msf.org/actualites/e...

Epicentre recrute un·e épidémiologiste ! Envie de participer à des études observationnelles, des enquêtes en population (mortalité, nutrition, séroprévalence), ou encore des études de cohorte, en soutien aux opérations MSF… 👉 postulez smrtr.io/sG2pz

Without radiotherapy, Malawi turned to neoadjuvant chemo + surgery for cervical cancer. 📊 A new study in Journal of Clinical Oncology compares 2-drug vs. 3-drug NACT regimens with no evidence that a 3DR improves operability or survival rates over a 2DR. ascopubs.org/doi/10.1200/...

🧪 In humanitarian crises, evidence saves lives. Epicentre’s editorial in MSF International Activity Report 2024 highlights how data, research & epidemiology guide life-saving decisions in the field. 📖 Read how science strengthens humanitarian action: 🔗 www.msf.org/internationa...

New from the endTB-Q trial: A 6–9 month oral BDLC regimen for pre-XDR TB showed promise — but only for patients with limited disease. For those with extensive TB, longer and stronger regimens are still needed. Full article @lancetrespirmed.bsky.social www.sciencedirect.com/science/arti...

In @WHO Bulletin, we analysed data from 12,000+ Nigerian children with severe malnutrition. Those with low WHZ face a higher death risk than those with low MUAC—especially when oedema is present. Special care needed. pmc.ncbi.nlm.nih.gov/articles/PMC...

Une récente enquête rétrospective de mortalité menée par @epicentre-msf.bsky.social auprès du personnel de MSF et de leurs familles révèle l'effroyable taux de mortalité résultant de la guerre totale d'Israël contre #Gaza, en particulier chez les enfants. www.msf.fr/communiques-...

A new mortality survey among MSF workers & their families in Gaza reveals the appalling death rate of Israel’s all-out war on Gaza, especially among children ·5× higher overall death rate ·10× higher for children under 5 ·6× higher for newborns (<1 month) epicentre.msf.org/en/news/gaza...

Great to see the IMVACS malaria vaccine trial advancing in Mali! Epicentre is proud to be part of this important study with local research teams in Mali and Burkina Faso to identify the most effective strategy to protect young children from malaria. www.imvacs.org/official-sta...

🔴SAVE THE DATE : Toutes les lignes rouges ont été franchies depuis longtemps à #Gaza. #MSF et de nombreuses autres organisations appellent à un grand rassemblement le 8 juillet à Paris. Plus nous serons nombreux·ses, plus notre voix sera entendue.

New study out GlobalHealthBMJ High mortality & violence among West Darfur refugees in Chad, 2023 First field-based mortality estimates since Sudan conflict began—showing extreme levels of violence, esp. in El Geneina. #Sudan #Darfur #Chad #Refugees 🔗 gh.bmj.com/content/10/6...

🎬 Scientific Day replays are live! Watch sessions on cholera, malaria, TB, cancer and more 📺 epicentre.msf.org/en/scientifi...

🎥 Epicentre’s Scientific Day just wrapped up! Insightful talks, critical reflections and open discussions — that's what makes this day unique, and it's the participants who speak best of it. Next one? In a year. Don’t miss it! www.youtube.com/watch?v=Ernl...

📢 Just published in @nejm.org The GastroSAM study compared intravenous and oral rehydration in children with severe acute malnutrition. The results suggest current guidelines may need revision, in favor of IV rehydration. Read more ⤵️ epicentre.msf.org/en/news/new-...

📢 Our Annual Report is out! See how our work has helped to: • improve medical practices • inform strategic decisions • strengthen advocacy Read it here 👇https://epicentre.msf.org/sites/default/files/2025-05/Annual_Report_Epicentre_2024.pdf

The Scientific Day is over for this year. Thanks to all participants. See you next year, and in the meantime you can watch all the presentations in the replay on this site. www.youtube.com/channel/UCpN...