Anita Meier
@anitafmeier.bsky.social
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Virologist at ETHZ sharing my fascination for viruses
Zika virus induces nanotube formation 👾 in the host cell to facilitate viral spread. ZIKV even uses them to acquire mitochondria from neighbouring uninfected cells!
4 days ago
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Epstein-Barr virus encodes a protein called EBNA1, which physically tethers 🤝 the viral DNA to the host chromosome so it doesn't get lost during mitosis.
www.cell.com/cell/fulltex...
3 months ago
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Anita Meier
Sonja Schmid
4 months ago
💥 We have 3 positions open in my lab in Basel, Switzerland🇨🇭:
#nanopores
#smFRET
#biomolecular
#dynamics
#singleMolecules
We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech. Please share broadly, thank you!🤝
schmid.chemie.unibas.ch
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Home | Research Group Schmid | University of Basel
https://schmid.chemie.unibas.ch/en/
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Anita Meier
Vicki Metzis
4 months ago
Application deadline for up to 5
@mrc-lms.bsky.social
postdoc positions in developmental epigenetics closes soon - don’t miss out! Positions across both experimental and computational projects. Come and join our fantastic team science community!
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Don't forget to sign up to reserve your spot! 🍿🥂🍪Signing up now will also ensure that we order enough drinks and snacks!
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5 months ago
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Herpes simplex virus type 1 (HSV-1) infections dramatically change the architecture of the host nucleus. HSV-1 specifically recruits certain host factors (e.g. RNAPII) to promote its replication. HSV-1 actively rewires the human genome! 😲Look at how the host genome gets squeezed!!
5 months ago
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Sjors Scheres
5 months ago
We have a 3-year funded postdoc position to work on structures of
#amyloid
filaments. If you are an expert in protein biochemistry, structural biology or
#cryoEM
/
#cryoET
, this could be for you! Feel free to email me with any questions. Come join us! 🤩
www.nature.com/naturecareer...
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Postdoctoral Scientist - Structural Studies - Dr Sjors Scheres - LMB 2640 - Cambridgeshire job with MRC Laboratory of Molecular Biology (LMB) | 12840844
Postdoctoral Scientist Starting Salary: £41,344 Fixed term: 3 years MRC Laboratory of Molecular Biology, Cambridge, UK We are looking for a postdoc...
https://www.nature.com/naturecareers/job/12840844/postdoctoral-scientist-structural-studies-dr-sjors-scheres-lmb-2640/?LinkSource=PremiumListing
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Louise Fets
5 months ago
#JobAlert
! We have an opening for a postdoctoral scientist in
#CancerMetabolism
in my lab
@mrc-lms.bsky.social
. If you're interested in the role of metabolism in drug response and resistance in cancer, and would like to work in a fun and friendly team, check it out:
lms.mrc.ac.uk/work/vacanci...
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MRC Postdoctoral Research Scientist - MRC Laboratory of Medical Sciences
The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. LMS...
https://lms.mrc.ac.uk/work/vacancies/mrc-postdoctoral-research-scientist-6/
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💥Our next AWA event is all about networking, mentorship and how to do it in a way that is right for you.😌 Sign up and come along. Everyone from Imperial/ MRC welcome! Limited spaces available, drinks and snacks included 🥂🧀
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5 months ago
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Ilaria Belluomo
5 months ago
🌟 The next event of the Academic Women Association (AWA) is happening! Registration and details here:
www.eventbrite.co.uk/e/academic-w...
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This is a tupanvirus, ~450nm in diameter ~1.2um in length, clearly one of the giant viruses. It encodes for the most complete translational machinery found in viruses with only the ribosome lacking. Most (non-giant) viruses don't encode any components required for translation. It's so fluffy!! 😱
5 months ago
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Blows my mind 🤯 that it is possible to capture the structural dynamics of viral capsid contraction by thawing and re-freezing the ice within the electron microscope! Anyone interested in microsecond time-resolved cryo-EM should check out this paper:
www.nature.com/articles/s41...
5 months ago
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Weird virus fact: Bacteriophage 29 (Phi29) uses RNA to help package genomic DNA 🤯. This so-called packaging RNA (pRNA) is an essential part of the packaging motor, which is part of the newly formed viral capsid. Check out the pRNA (pink) in the beautiful structure:
www.science.org/doi/10.1126/...
6 months ago
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Weird virus fact: Papillomaviruses can make their host cell immortal 🧟♂️ by activating telomerase (together with other mechanisms). The viral protein E6 regulates and directly interacts with hTERT and telomeric DNA.
6 months ago
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Weird virus fact: Adeno-associated viruses (AAV) can only replicate if the same host cell is infected with a helper virus. AAV will remain in the host cell (latently infecting it) until a helper virus such as HSV or AdV comes along.
www.mdpi.com/1999-4915/12...
7 months ago
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Weird virus fact: HIV-1 and other retroviruses hijack cellular tRNA and use it as primer to initiate reverse transcription of their RNA genome. They exploit the same tRNA terminal 3′-OH group used by the host for aminoacylation and peptidyl transfer.
7 months ago
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Weird virus fact: In order to overcome the end replication problem, adenovirus DNA replication starts at a protein, rather than an RNA primer. The viral polymerase couples the first nucleotide (dCTP) to a serine on the terminal protein, which assures full replication by a jump-back mechanism. 😎
8 months ago
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I fear the consequences of this move...
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8 months ago
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Weird virus fact: The SV40 polyomavirus dsDNA genome is wrapped around cellular histones within the viral capsid. Most
#viruses
don't contain histones in their virions.
www.sciencedirect.com/science/arti...
Image credit:
viralzone.expasy.org/148
8 months ago
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Great opportunity for people at Imperial/ LMS too meet and network. Sign up if interested!
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8 months ago
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Weird virus fact: Herpesvirus (HSV-1) assimilates the cellular motor kinesin-1 to travel within the cell. HSV-1 takes it up into the tegument to use it for future infection:
www.nature.com/articles/s41...
8 months ago
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reposted by
Anita Meier
MRC Laboratory of Molecular Biology
8 months ago
There’s still time to apply to the LMB’s Rising Talent Fellowship for Black heritage scientists. With this 3-year postdoc position we want to enable scientists of Black heritage to learn & grow their experience. Application deadline: 23 March More info:
www2.mrc-lmb.cam.ac.uk/recruitment/...
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Weird virus fact: Influenzaviruses chop off the 5'-mRNA cap of nascent host mRNA and use it for their own mRNA. This is called cap-snatching Further reading:
pmc.ncbi.nlm.nih.gov/articles/PMC...
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Insight into Influenza: A Virus Cap-Snatching
The influenza A virus (IAV) genome consists of eight single-stranded RNA segments. Each segment is associated with a protein complex, with the 3′ and 5′ ends bound to the RNA-dependent RNA polymerase ...
https://pmc.ncbi.nlm.nih.gov/articles/PMC6266781/
8 months ago
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Anita Meier
Erin E. Cutts
8 months ago
Anyone looking for a PhD: the second deadline of the Yorkshire DTP closes this Friday, the 14th. Get in touch asap if you are interested in working with me on condensin complexes!
www.findaphd.com/phds/project...
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Developing Imaging Solutions to Study the Dynamics of Human Condensin I at University of Sheffield on FindAPhD.com
PhD Project - Developing Imaging Solutions to Study the Dynamics of Human Condensin I at University of Sheffield, listed on FindAPhD.com
https://www.findaphd.com/phds/project/developing-imaging-solutions-to-study-the-dynamics-of-human-condensin-i/?p177759
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Scary... “For all this talk about free speech, this is direct censorship of scientific research.” Lisa Fazio
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8 months ago
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Nature
8 months ago
In an unprecedented move, the US National Institutes of Health has begun mass terminations of research grants that fund active scientific projects because they no longer meet “agency priorities”.
https://go.nature.com/4bpG2It
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Exclusive: NIH to terminate hundreds of active research grants
Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.
https://go.nature.com/4bpG2It
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Are you at
#bps2025
and want to hear about: HSV-1 DNA replication, DNA looping,
#smFRET
, TIRF, optical tweezers or cryoEM? Come and talk to me at my poster B175 on Wed, 10.30am!
9 months ago
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reposted by
Anita Meier
Erin E. Cutts
10 months ago
For anyone that was too busy at the end of last year to think about PhDs or are still looking for the right project/place, I have a project available in the second round of the Yorkshire Biosciences DTP scheme looking at the dynamics of human condensin:
www.findaphd.com/phds/project...
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Developing Imaging Solutions to Study the Dynamics of Human Condensin I at University of Sheffield on FindAPhD.com
PhD Project - Developing Imaging Solutions to Study the Dynamics of Human Condensin I at University of Sheffield, listed on FindAPhD.com
https://www.findaphd.com/phds/project/developing-imaging-solutions-to-study-the-dynamics-of-human-condensin-i/?p177759
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