@nstoesser.bsky.social
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Hoping to innovate community population-level AMR surveillance with the ALARUM team
bmjopen.bmj.com/content/16/2...
. Can we use metagenomics of pooled colonisation samples to predict clinical AMR burden & inform antimicrobial guidelines?
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ALARUM: Active One Health surveillance in LMICs to monitor and predict Antimicrobial Resistance Using Metagenomics – a cross-sectional study protocol
Background In rural sub-Saharan Africa (sSA), the burden of antimicrobial resistance (AMR) remains high. As AMR continues to rise, there is a strong need for practical, implementable surveillance to m...
https://bmjopen.bmj.com/content/16/2/e107465
3 months ago
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Are you a post-doctoral microbiologist interested in characterising bacterial resistance evolution and want to apply your knowledge and expertise to developing new therapeutics for Klebsiella (and other Enterobacterales) infections? Then we need you! Apply now
bit.ly/3MX39Ce
close date March 13th đź‘€
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Job Details
https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_company=10&p_internal_external=E&p_display_in_irish=N&p_process_type=&p_applicant_no=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y&p_recruitment_id=184906
3 months ago
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reposted by
Alasdair Hubbard
4 months ago
🚨 Fully‑funded PhD for Home Students🚨 We'll explore non-antibiotic alternatives in relatistic environments, uncovering how they work, if they affect antibiotic activity and whether they influcence AMR acquistion. Come join a wonderful supervisory team!
#MicroSky
#UTISky
#AMar
tinyurl.com/38u552bu
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Optimising the use of alternative therapies for the treatment of urinary infections - The University of Nottingham
https://tinyurl.com/38u552bu
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reposted by
Matthew J Shepherd
3 months ago
🚨 New pre-print! 🚨 In the largest study of its kind to-date, we investigate the ecological and evolutionary mechanisms driving within-patient evolution of antimicrobial resistance (AMR). Read here:
www.biorxiv.org/content/10.6...
, and follow along with this thread, discussing our findings (1/21)
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https://www.biorxiv.org/content/10.64898/2026.02.18.705331v1
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If you're interested, click on
www.ox.ac.uk/admissions/g...
- Life and Medical Sciences, Clinical Medicine 04!
add a skeleton here at some point
3 months ago
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By Shireen Kotay/Amy Mathers - Biofilm removal in hospital sink drains drives unintended surges in antibiotic resistance
rdcu.be/e1uTu
. Effects akin to gut microbiome dysbiosis/loss of colonisation resistance. To mitigate these reservoirs we need better evidence to understand what works best where.
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Biofilm removal in hospital sink drains drives unintended surges in antibiotic resistance
npj Antimicrobials and Resistance - Biofilm removal in hospital sink drains drives unintended surges in antibiotic resistance
https://rdcu.be/e1uTu
4 months ago
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Our project "Sardinia’s Invisible Marine Microbiome" is one of six 2026
#PartArt4OW
participatory art initiatives! Excited to do this with the brilliant
@annadumitriu.bsky.social
(image credit), Sardinian scientists, citizens of Alghero, and colleagues in
@modmedmicro.bsky.social
@bashthebug.net
4 months ago
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Delighted to be involved in the Gram-Negative Antibiotic Discovery Innovator (Gr-ADI) consortium
novonordiskfonden.dk/en/news/new-...
as part of a project led by Annette von Delft
gcgh.grandchallenges.org/grant/discov...
@modmedmicro.bsky.social
@samlipworth.bsky.social
@philipwfowler.bsky.social
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Discovery of Novel Klebsiella Hits Through In-Depth Genomic Profiling, Fragment-Based Drug Design and Accumulation Assays
Annette von Delft and collaborators Nicole Stoesser, Lizbe Koekemoer, Ed Griffen, Paul Brennan, Frank von Delft, Phil Fowler, and Thomas Lanyon-Hoggat of the University of Oxford in the United Kingdom...
https://gcgh.grandchallenges.org/grant/discovery-novel-klebsiella-hits-through-depth-genomic-profiling-fragment-based-drug-design
4 months ago
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Univ of Oxford UNIQ+ scheme applications open: 7-week research internship this Summer
www.ox.ac.uk/admissions/g...
. Lots of projects - one in our lab on microplastics & AMR & hospital environments at
@modmedmicro.bsky.social
led by Aram Swinkels
www.ox.ac.uk/admissions/g...
(Clin Med 04). Join us!
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What is UNIQplus? | University of Oxford
The UNIQplus programmeThe UNIQplus programme is aimed at supporting talented undergraduates from under-represented groups, who would find continuing into postgraduate study a challenge for reasons
https://www.ox.ac.uk/admissions/graduate/access/uniq-plus/about
4 months ago
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New out by
@dotnagy.bsky.social
& colleagues synthesising published epidemiological/microbiological/genomic data on 'big 5' CPE hospital outbreaks:
www.medrxiv.org/content/10.6...
Lots of them, but sampling and reporting heterogeneity makes it hard to nail risk factors for dissemination.
5 months ago
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reposted by
Bash the bug
6 months ago
Our team wore blue for World Antimicrobial Awareness Week 2025đź’™ Research into how resistance emerges, spreads and can be prevented is vital. Our group works to understand these processes and develop better tools to detect, monitor and combat antimicrobial resistance.
#WAAW
@oxfordbrc.bsky.social
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reposted by
Sam Lipworth
8 months ago
Pleased to see this out today in
@lancetmicrobe.bsky.social
www.sciencedirect.com/science/arti...
. We estimate the independent effects of AMR genes on MIC at a drug-bug level and challenge the idea that resistance is a binary phenomenon.
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Estimating the association of antimicrobial resistance genes with minimum inhibitory concentration in Escherichia coli: an observational study
Surveillance and prediction of antibiotic resistance in Escherichia coli relies on curated databases of genes and mutations. We aimed to quantify the …
https://www.sciencedirect.com/science/article/pii/S2666524725001119
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reposted by
Will Matlock
8 months ago
Now published in
@natcomms.nature.com
🎉
www.nature.com/articles/s41...
With Gillian Rodger,
@nstoesser.bsky.social
,
@samlipworth.bsky.social
,
@stat-sarah.bsky.social
, and many others!
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reposted by
Dorottya Nagy
8 months ago
Pleased to see this pre-printed, highlighting the completeness/accuracy of
@nanoporetech.com
long-read genome assembly for clinical Enterobacterales:
www.biorxiv.org/content/10.1...
Thanks to colleagues
@modmedmicro.bsky.social
,
@ukhsa.bsky.social
,
@genewiz.bsky.social
and
@oxfordbrc.bsky.social
!
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Job opportunity for microbial genomicists interested in E. coli and Klebsiella infections and AMR 👀⬇️ - do get in touch if you might be interested! Closing date 7th Oct.
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8 months ago
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Great new opportunity to work with
#Liamshaw
and
@mutantbug.bsky.social
as part of our HPRU collaboration (
www.expmedndm.ox.ac.uk/research/hpr...
) - sinks, phages, wastewater genomes, novel threat detection
bit.ly/45Wcv6I
- deadline 14th Sept đź‘€
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Details | Working at Bristol | University of Bristol
https://bit.ly/45Wcv6I
9 months ago
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New analysis from Kevin Chau
@modmedmicro.bsky.social
for the SinkBug Consortium (a collaboration with teams across 29 UK hospitals, NITCAR, UKHSA): Pathogen and AMR gene burden in 287 hospital sink-trap metagenomes and factors associated with high burdens.
add a skeleton here at some point
10 months ago
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you reached the end!!
feeds!
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