Shashank Pritam
@shashankpritam.bsky.social
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shuh-SHAHNK | PhD Candidate, Computational Biologist
reposted by
Shashank Pritam
Dr. Sarah Signor
1 day ago
So often you can find a story to tell in RNAseq data, but how real is it really? Here we independently replicated evolution by genetic accommodation in D. melanogaster!!! Congrats George!!
onlinelibrary.wiley.com/doi/10.1002/...
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Evolution of Plasticity in Response to Ethanol Between Recently Separated Populations of D. melanogaster With Different Ecological Histories
We identified: (1) differences in gene expression among each locale; (2) changes in gene expression in response to treatment; (3) genotype-specific changes in gene expression in response to treatment
https://onlinelibrary.wiley.com/doi/10.1002/ece3.72874
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Authenticity struggles in a world run by projections.
about 1 month ago
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reposted by
Shashank Pritam
Dr. Sarah Signor
about 2 months ago
Last night in North Dakota
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reposted by
Shashank Pritam
Steam Deck
about 2 months ago
Welcome to fam, ya'll! -Steam Controller -Steam Machine -Steam Frame (Growing our
@steampowered.com
Hardware Family in early 2026)
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reposted by
Shashank Pritam
Dr. Sarah Signor
2 months ago
My awesome grad student Shashank and I wrote this paper trying to look at broader patterns of HT in TEs. HT is happening everywhere! DNA transposons jump further than other classes!
www.biorxiv.org/content/10.1...
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Recent horizontal transfer of transposable elements in Drosophila
Transposable elements (TEs) are genetic elements also known as "jumping genes" that increase their copy numbers within a host through various mechanisms of transposition. TEs can also move between spe...
https://www.biorxiv.org/content/10.1101/2025.10.30.685650v1
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GOATed:
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Mezzanine (Deluxe) - Album by Massive Attack
Mezzanine is the third studio album by English electronic music group Massive Attack, released on 20 April 1998 by Circa and Virgin Records. For the album, the group began to explore a darker aestheti...
https://music.youtube.com/playlist?list=OLAK5uy_myCWwyHEz9SABGUHaclijR2o9zLXJdE_w&
3 months ago
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reposted by
Shashank Pritam
Alexis Verger 🧬🧫🧪
3 months ago
iFold, sorry, SimpleFold, by Apple
arxiv.org/html/2509.18...
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SimpleFold: Folding Proteins is Simpler than You Think
https://arxiv.org/html/2509.18480
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reposted by
Shashank Pritam
Jim Shaw
4 months ago
Preprint out for myloasm, our new nanopore / HiFi metagenome assembler! Nanopore's getting accurate, but 1. Can this lead to better metagenome assemblies? 2. How, algorithmically, to leverage them? with co-author Max Marin
@mgmarin.bsky.social
, supervised by Heng Li
@lh3lh3.bsky.social
1 / N
add a skeleton here at some point
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Imagine Sisyphus on the Ship of Theseus! hehe, btw highly recommend this 2012 movie by Anand Gandhi.
add a skeleton here at some point
4 months ago
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reposted by
Shashank Pritam
Dr. Sarah Signor
4 months ago
Tenure seminar, done!
add a skeleton here at some point
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Listen to Niche Radio from Navi Mumbai live on Radio Garden
Listen to Niche Radio from Navi Mumbai live on Radio Garden
https://radio.garden/listen/niche-radio/KAjTkgNu
4 months ago
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reposted by
Shashank Pritam
Chad
4 months ago
@tangled.sh
search interface if you need it.
tangled-search.bigmoves.deno.net
. Example of what you can build with Slices (an appview builder) and the power of the
#atprotocol
. Still working through all the details but waitlist and beta for Slices are coming soon!
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Ten Ragas To A Disco Beat - Album by Charanjit Singh
Listen to Ten Ragas To A Disco Beat by Charanjit Singh on YouTube Music - a dedicated music app with official songs, music videos, remixes, covers, and more.
https://music.youtube.com/playlist?list=OLAK5uy_ns6NBSFplPNSaDfdGJuWou3yh1hdW4PG0
4 months ago
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radio.garden/listen/radio...
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Listen to Radio Schizoid - Dub Techno from Mumbai live on Radio Garden
Listen to Radio Schizoid - Dub Techno from Mumbai live on Radio Garden
https://radio.garden/listen/radio-schizoid-dub-techno/qxvYAkWS
4 months ago
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reposted by
Shashank Pritam
Matt Beaumont
4 months ago
Germline defence from TEs largely relies on piRNAs. Yet,
@divyaselvaraju.bsky.social
and I monitored a P-element invasion in Drosophila that was stopped by an internally deleted copy, no host intervention required!
doi.org/10.1371/jour...
Many thanks to
@rpianezza.bsky.social
&
@rokofler.bsky.social
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Rapid emergence of non-autonomous elements may stop P-element invasions in the absence of a piRNA-based host defence
Author summary Transposable elements (TEs) are short, self-replicating DNA sequences found in nearly all genomes. While they can be harmful to their hosts, many organisms have evolved defence systems,...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011649
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www.asimov.press/p/a-visual-g...
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A Visual Guide to Genome Editors
A selected encyclopedia of major gene-editing systems, together with illustrated diagrams.
https://www.asimov.press/p/a-visual-guide-to-genome-editors
4 months ago
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www.asimov.press/p/insect-dia...
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Pausing Insect Activity
Seasonal dormancy features in the life cycle of many insects. We can harness it for biological control, insect farming, and disease vector management at scale.
https://www.asimov.press/p/insect-diapause
4 months ago
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reposted by
Shashank Pritam
Dr. Sarah Signor
5 months ago
The Signor lab is loving our new lab shwag, designed by the ever wonderful
@nepeteaa.bsky.social
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reposted by
Shashank Pritam
Dr. Sarah Signor
5 months ago
@shashankpritam.bsky.social
first research paper on the effect of insertion bias on transposon fitness!! With
@almoroscarpa.bsky.social
and
@rokofler.bsky.social
link.springer.com/article/10.1...
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The impact of insertion bias into piRNA clusters on the invasion of transposable elements - BMC Biology
Background In our current understanding of transposable element (TE) invasions, TEs move freely until they accidentally insert into a piRNA cluster, where they are silenced by the production of piRNA ...
https://link.springer.com/article/10.1186/s12915-025-02370-0?utm_source=rct_congratemailt&utm_medium=email&utm_campaign=oa_20250815&utm_content=10.1186%2Fs12915-025-02370-0
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reposted by
Shashank Pritam
Dr. Sarah Signor
10 months ago
Such a great poster session at
#dros25
. Need to refuel before everything you want to know about sex
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reposted by
Shashank Pritam
Dr. Sarah Signor
about 1 year ago
Look at this prince
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reposted by
Shashank Pritam
Dr. Sarah Signor
about 1 year ago
My graduate student shashank and I wrote this cool review on the evolution of transposon defense. Come for pirna cluster evolution stay for wild theories!
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Evolution of piRNA-guided defense against transposable elements
Transposable elements (TEs) shape every aspect of genome biology, influencing genome stability, size, and organismal fitness. Following the 2007 disco…
https://www.sciencedirect.com/science/article/pii/S0168952524002932?dgcid=author
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Flowers
over 1 year ago
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Iguana skeleton
over 1 year ago
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Snake
over 1 year ago
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Squirrel
over 1 year ago
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Rabbit
over 1 year ago
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Fish
over 1 year ago
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Flowers
over 1 year ago
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Flowers
over 1 year ago
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Flowers
over 1 year ago
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Don't be motivated by the fear of failure and future!
over 1 year ago
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