Do all #NTFs regulate #MotorNeuron axonal transport in vivo? Our new preprint shows they do not. #BDNF enhances (shorturl.at/siwFi), #CNTF slows, and #HGF, #NRTN & #proBDNF show no effect. #AxonalTransport regulation is selective, not universal. @jamessleigh.bsky.social @uclqsion.bsky.social

OMG, this is such a cool paper from Patrick Caswell's lab. They express Rab25-mCherry-GFP-nanobody in cells, microinject GFP-magnetic particles, then use a magnet to pull Rab25 to the plasma membrane to show that it can trigger actin protrusions! I want this system. www.science.org/doi/10.1126/...

Our new paper in Neurobiology of Aging showing that processivity and BDNF-dependent modulation of #AxonalTransport are impaired in aged mice: www.sciencedirect.com/science/arti... @dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social @uclqsion.bsky.social #aging

Short perspective from Dr. Ellie Rhymes on shared mechanisms and phenotypes in ARS-related neuropathies: journals.lww.com/nrronline/ci... #CMT #neuropathy #PeripheralNerve