New article: AI can transform chronic pain care, but without the right human input, it risks compounding the very problems it aims to solve. We suggest to build it in a way so that we can understand pain. Hashmi MA & Hashmi JA, PAIN (2026) doi.org/10.1097/j.pa... l1nq.com/lg9vhcq

How it's going.

Our latest work looking at the neuroanatomical basis of impulsivity in youth is out now in Molecular Psychiatry!

New paper in PNAS! When the mind wanders, it often drifts to the body. We call this "body-wandering". These thoughts are often negative, but are associated with reduced ADHD & depression symptoms, driven by a distinct interoceptive-allostatic brain signature. pnas.org/doi/10.1073/pnas.2520822123

More evidence that the homeostatic pathway lamina 1 theory has no feet.

Is there a single "interoceptive sense"? Our new study in @commspsychol.nature.com says: probably not. In 241 participants, cardiac and respiratory interoception were completely uncorrelated — only subjective confidence was shared across domains. www.nature.com/articles/s44... #psychscisky 🧪

Another day, another stupid Excel chart.

🔥My first paper is out in Synthese — open access: “From simulating to duplicating the brain”🔥 link.springer.com/article/10.1... Abstract below. Would love to hear what you think (and especially any objections / counterexamples). @springernature.com

New paper in Imaging Neuroscience by Maëlig Chauvel, Cyril Poupon, et al: Evolutionary signatures in deep white matter architecture: A comparative study of humans and chimpanzees doi.org/10.1162/IMAG...

preprint🥳 Connectome-wide mega-analysis identifies a reproducible functional network signature of temporal lobe epilepsy -hypo+hyper connectivity -patient/site consistent -constrained by 🧠 wiring -tracks clinical status and info for outcome by @kexie.bsky.social et al doi.org/10.64898/202...

Check out our new paper, and join this webinar where @drjkhokhar.bsky.social and I will discuss the science and more! www.eneuro.org/content/13/2...

I love the internet Don't be so careful in time of death ✊😔

Excited to share this in final form @sfnjournals.bsky.social: An Open-Source Restraint System for Magnetic Resonance Imaging in Awake Rats www.eneuro.org/content/13/2... if anyone wants to try doing it, give us a call! Happy to help you get going!

The strongest version of this illusion I’ve seen! Absolute head-wrecker!

This piece really nails how I have been feeling in the last couple of weeks. fortune.com/2026/02/11/s...

"..hippocampal-prefrontal systems represent emotion concepts in a map-like way at multiple levels of abstraction.." Map-like representations of emotion knowledge in hippocampal-prefrontal systems by @yumengma.bsky.social and @pkragel.bsky.social www.nature.com/articles/s41...

Well-predicting machine learning in no way means that you can understand how the world works. open.substack.com/pub/kording/...

As Joe says! Hear, hear. www.thetransmitter.org/the-big-pict...

Sir Ian McKellen performing a monologue from Shakespeare’s Sir Thomas More on the Stephen Colbert show. Never have I heard this monologue performed with such a keen sense of prescience. Nor have I ever been in this exact historical moment.TY Sir Ian, for reaching us once again. #Pinks #ProudBlue

The cortex layer 6b theory of attention www.cell.com/neuron/fullt...

For aficionados of timing, prediction, psychophysics-and anyone who wants to look at something other than the news to be distracted-a new study by Matthias Grabenhorst and Georgios Michalareas: The anticipation of imminent events is time-scale invariant www.pnas.org/doi/epdf/10.... #neuroskyence

Initiating grant spiral 🌀 If you need me, leave offerings of coffee and low expectations. #AcademicLife #FundedOrFeral

New paper led by wonder postdocs Francesca Greenstreet and @jessegeerts.bsky.social and @clopathlab.bsky.social trying to understand why –in the "what for" sense– there are multiple motor learning systems –supervised and RL-based– in the brain. Check out Jesse's 🧵 www.biorxiv.org/content/10.6...

𝗖𝗮𝗻 𝘄𝗲 𝘀𝘁𝘂𝗱𝘆 𝗯𝗿𝗮𝗶𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝘄𝗶𝘁𝗵 𝗳𝗠𝗥𝗜? We employed Switching Linear Dynamical Systems to investigate the dynamics of resting-state networks They are dynamic, not static! Work with Xiaoyu Zhao with lots of new methods. Thread. #neuroskyence www.biorxiv.org/content/10.6...

human, macaque, marmoset!

“The fact that we can make disastrous decisions even as we foresee their consequences is the great, unsolved mystery of human behavior.” —Slavoj Zizek Photo: Andy Miah | #SlavojZizek #literature #quotes #fblifestyle #philosophy

**How distributed is the brain-wide network that is recruited for cognition?** That goes to the top of the list! #neuroskyence doi.org/10.1038/s415...

Good stuff. thanks @pessoabrain.bsky.social

New paper in Imaging Neuroscience by Hecheng Jin, Ting Xu, et al: Is Pearson’s correlation coefficient enough for functional connectivity in fMRI? doi.org/10.1162/IMAG...

“Vanity of vanities… all is vanity. You kill yourself to get to the grave. Especially you kill yourself to get to the grave before you die; and the name of the grave is ‘success’, the name of that grave is hullabullo boom boom horseshit.” —Jack Kerouac

Zohran flip your hair again we need healthcare get him to give us healthcare.

“There’s a popular view that connectivity, in the Facebook sense, is a good thing. In my world, it’s really bad. Dense connectivity is the killer. It is death.” — Karl Friston. hbarjournal.substack.com/p/karl-frist...

Very cool new work from the Iglesias group at MGH: A probabilistic histological atlas of the human brain for MRI segmentation (also available at OpenNeuro - openneuro.org/datasets/ds0...) : www.nature.com/articles/s41...

fun old experiment (1968): O. Lippold believed that the alpha rhythm was related to the physiological tremor in eye muscles (also ~10 Hz). so in this experiment, the eyeball was cooled & warmed to shift the muscle tremor frequency. when they measured EEG, the alpha frequency seems to change.

Towards a computational phenomenology of meditative deconstruction: modelling ‘letting go’ and the deconstruction of experience with active inference osf.io/preprints/ps...

My paper is out! Computational modeling of error patterns during reward-based learning show evidence that habit learning (value free!) supplements working memory in 7 human data sets. rdcu.be/eQjLN

AI is growing exponentially at a timescale of months while the economy is growing at a timescale of decades. How should we model the economy with rapidly increasing intelligence tech and slowly increasing physical tech? New AI+econ paper.

Heart rate variability (HRV) is one of the widely used physiological measures in psychophysiological research. But with over 100 indices to choose from, how do we know which ones to use? In our latest paper, we take a data-driven approach to help answer this. doi.org/10.1111/psyp... 1/

Enteric neurons join the pain conversation! New paper shows that cholinergic circuits in the colon signals through DRG pathways, especially after inflammation. www.cell.com/neuron/fullt...

I woke up this morning thinking: We. The. People. That’s mighty nice.

Can machine learning really beat classic stats at classifying chronic pain? Excited to share the first in our series of papers using hypothesis-driven analyses to identify reproducible, verifiable biomarkers of chronic pain. We validated findings across three cohorts (N=197). #PainResearch #ML #AI

Can the motor system use sensory expectations to prepare for unexpected events? Excited to share my latest work with @andpru.bsky.social – where we establish that sensory expectations shape neural population dynamics in motor circuits! 🧵 and paper below 1/

"these arrangements are not 'partnerships' or 'collaborations' but contracts that bring profit and publicity to AI firms, while making universities complicit in the continued empowerment of tech oligarchy and expansion of their 'AI Empire' (Tacheva and Ramasubramanian, 2023; Adams, 2024; Hao, 2025)"

"My candy is more of a comment"