www.dzif.de/en/how-hiv-e... @dzif.bsky.social @dfg.de @natmicrobiol.nature.com #HIV #HIVScience #HIVCure #Nucleus #Nucleararchitecture #Splicing #R-loops #Genomeorganization

Researchers from CSSB & @mpi-nat.bsky.social have generated a highly potent nanobody that neutralizes a protein essential for the herpes virus infection. Published in @nature.com, the findings promise new therapies to treat & prevent infections @leibnizliv.bsky.social @uni-hamburg.de t1p.de/cxt7a

Our work "Aquarius helicase facilitates HIV-1 integration into R-loop enriched genomic regions" is out @natmicrobiol.nature.com, showing HIV-1 integration into R-loop genomic regions upon their resolution by cellular splicing helicase Aquarius (AQR) of the Intron Binding Complex (IBC)🧵.

#Tuberculosis poses a serious threat to people with weakened immune systems. However, standard testing is not sufficient for reliable TB diagnosis or prediction, as a high-profile study involving more than 2,600 patients from eleven European countries revealed @fzborstel.bsky.social @uni-saarland.de

Why are communities key to research—and why does language matter in science? Watch DZIF scientists and Marc Franke, one of the few cured of #HIV & DZIF Patient Advisory Board member, in a talk from #AIDS2024 in Munich. 🎤📺 ▶️ t1p.de/a3p82 @fraukemuecksch.bsky.social @raifderrazi.bsky.social

🚀 New in Advanced Science: RAB5A drives active fluid wetting in breast cancer spheroids by reprogramming cell mechanics. doi.org/10.1002/advs... 👏 Kudos to first author Grégoire Lemahieu and our amazing co-authors for this joint effort! #CancerMechanobiology #CellAdhesion #RAB5A #TeamScience

Now out in ACS Infectious Diseases @pubs.acs.org: joint work from the Lanzer, Tanaka, Schwarz and Cavalcanti-Adam labs within #SFB1129 on the adhesion footprint of malaria-infected infected red blood cells. Read the open access paper here: pubs.acs.org/doi/10.1021/...

🌍👩🏾‍🔬Backed by #ChooseEurope, which aims to attract top global talent, the programme will boost EU competitiveness & improve the well-being of its people. It will build on past success by scaling proven solutions & investing where it’s most needed. Learn more 💶 europa.eu/!w77nKY #ThePowerOfTogether

Opening for a professorship in multimodal imaging in the context of our cluster of excellence #3DMM2O. Here is the full advertisement with all details: tinyurl.com/2ksy2b2s

Very inspiring, but also sort of sad: last of the annual retreats of our wonderful #SFB1129 on pathogens, which just entered its 12th and last year. But there is also some good news: it will end in one year from now with an international conference that everyone will be able to attend👍😀

Viruses under the super microscope: How influenza viruses communicate with cells @helmholtzhzi.bsky.social‬ #influenza #viruses #virology #microscopy

#Measles can be fatal. Do you know its symptoms? 🔸 Rash that starts on the face and spreads over the body 🔸 Fever 🔸 Runny nose 🔸 Cough 🔸 Red and watery eyes 🔸 Small white spots inside the cheeks Seek health care if you suspect you or your child has measles.

Welcome to CIID @munschauerlab.bsky.social! We are looking forward to having you here and to many fruitful and exciting years of working together!

We are excited to announce that the jGfV Virtual Lecture Series is now also available On-Demand for all GfV-Members! See below on how to get started. Enjoy the first lecture "How to eradicate a virus" given by Dr. Sindy Böttcher and Prof. Klaus Überla in case you have missed it

#Measles can lead to severe, long-term complications and can even cause your immune system to forget how to resist infections. 🔸Brain damage 🔸Severe diarrhoea and dehydration 🔸Deafness 🔸Blindness 🔸Pneumonia

🦢 Avian Influenza Update | March–June 2025 New EU joint report from EFSA, @ecdc.europa.eu and EU Reference Lab shows a decline in #HPAI cases across Europe this spring. Key takeaways in the animation below. 📄 Full report → europa.eu/!RVJX3r #BirdFlu #EFSA #AnimalHealth #PublicHealth

Die Abteilung Virologie am Zentrum für Infektiologie lädt gemeinsam mit der Aidshilfe Heidelberg am 1. Juli 2025 um 17 Uhr in die Heidelberger Akademie der Wissenschaften am Karlsplatz zu einer interaktiven Veranstaltung ein.

Finally published: discovery of an unusual Arp2/3 complex with surprising new function in transmission of #malaria #parasites. Great work by Franzi Hentzschel, Yvonne Sokolowski + David Jewanski + fantastic collaboration with Matthias Marti: www.nature.com/articles/s41...

We are happy this work by Sarah Peterl et al. is out in EMBO J! It was an exciting collaborative effort of several groups in the SFB1129 consortium on pathogen replication and spread. Check out the correlated light and scanning EM method to study virus morphology changes during spread!

The new excellence cluster GreenRobust is recognized by the local RNZ newspaper:

🚀🧪We’re proud to announce the launch of the European Vaccines Hub! This new EU-funded public-private partnership will serve as a central platform to strengthen vaccine development across Europe. The DZIF is playing a key role in the pan-European hub for pandemic preparedness 👉 t1p.de/European-Vac...

We have green light for the Cluster of Excellence "SynthImmune", coordinated by Oliver Fackler @ciid-heidelberg.bsky.social! Congratulations to everyone involved! www.uni-heidelberg.de/en/newsroom/...

Excellence cluster "SynthImmune" gets funded!! 🤩 Immunology in Infection and Cancer are now a center piece of the Heidelberg-Mannheim campus @hlsalliance.bsky.social! Congratulation to everyone involved with extra kudos to Oliver Fackler @ciid-heidelberg.bsky.social!

🦟🦠 BioMalPar XXI kicks off today at EMBL Heidelberg! Welcoming researchers from around the world to explore the biology and pathology of the malaria parasite. Excited for a week of science, collaboration, and discovery! #EMBLMalaria #BioMalParXXI #MalariaResearch #GlobalHealth

Researchers at the DKFZ and the Heidelberg University Hospital have discovered that the Epstein-Barr virus increases the ability of infected immune cells to migrate. In this way, the pathogen promotes its spread in the body - a potential approach for new therapies. t1p.de/g626g

The SynthImmune project by Heidelberg University& partner institutes advances a "bottom-up" synthetic biology approach to immunotherapies. Hoping they do well in the German government's Excellence Strategy—anticipating the announcement on 22 May. Perspective article: www.nature.com/articles/s41...

Second Heidelberg Interferons Symposium coming up!! If you are based in HD or Mannheim (@dkfz.bsky.social, @uniheidelberg.bsky.social, @hlsalliance.bsky.social, @embl.org,...) and interested in any facet of these incredible #cytokines, join us on 🗓️ July 10/11 🏫 Marsilius Kolleg ✍🏻 bit.ly/IFN2025

🔜 At the 2nd #LongCOVID Symposium of the German Centers for Health Research (#DZG), one session will focus on post-viral pulmonary health, with insights from clinical and translational lung research. 📅 Date: May 9, 2025 in Frankfurt 🔗 Full program & registration: deutschezentren.de/2nd-long-cov...

Unser Präsident Hans-Georg Kräusslich wurde zum Vizepräsidenten der @akademienunion.bsky.social gewählt. Wir freuen uns und gratulieren!

Congratulations Reiya Taniguchi on the fantastic study of nuclear pore stability linked to Nup133! 🍩 Check out this fantastic study of the @becklab.bsky.social , @vdoye.bsky.social lab and Georg-Kräusslich! www.nature.com/articles/s41...

Rich Condit Speaks with Stephan Urban about his career working on HBV and HDV and his philanthropy @ciid-heidelberg.bsky.social

One of the big success stories in current German virology: the discovery of a small peptide in the #Hepatitis B virus #HBV, and its development towards a clinical #HDV (and HBV!) entry inhibitor by Stephan Urban @ciid-heidelberg.bsky.social @uniheidelberg.bsky.social (MB) youtu.be/JcdtRNaTHpM?...

˚⋆🔬🧪Alliance Stimulator Grants🥽⋆˚ ‼️Closing soon: Apply by April 25, 2025‼️ This call is open for Alliance member institutions only! #interinstitutionalprojects, #translationprojects #interdisciplinaryprojects 👉More info on our webpage at: www.health-life-sciences.de/opportunitie...

#ChagasDisease has the most severe impact among Latin America's impoverished communities but it is increasingly detected in other parts of the world. 100M people are at risk of infection. bit.ly/3vFipLv

(1/3) Together with the labs of Valerie Doye @vdoye.bsky.social and Hans-Georg-Kräusslich, we analyzed NPC structure in Nup133 null mESCs. We found heterogenous NPCs featuring non-canonical symmetries and missing subunits. Now online @naturecellbiology.bsky.social. www.nature.com/articles/s41...

Great work on 3D chromatin from @becklab.bsky.social led by @jpkreysing.bsky.social and @sergiocruzleon.bsky.social in primary human resting CD4 T cells! Very happy to have contributed !

📢 Preprint alert 📢 (1/6) Our work on 3D force inference for intestinal organoids is now on bioRxiv: www.biorxiv.org/content/10.1... Stunning collaboration between @omdrozdowski.bsky.social and @kimboonekamp.bsky.social from the lab of @michaelboutros.bsky.social and with Ulrike Engel. A short🧵...

Measles is a serious disease. 1 in 5 children who are infected with measles end up in hospital, often with pneumonia. Children can also suffer complications, such as deafness, blindness, or even brain damage. No parent wants to see their child end up in hospital.

We are excited to share that our NanoX project has been featured in the Rhein-Neckar-Zeitung @rnzonline.bsky.social! Thank you to Amira Sanli for visiting our laboratories and showcasing our work in the newspaper! #NanoX #HepatitisE #softxraytomography #cellbiology

💊 Don't miss the #VallHebronTalks! Tomorrow, DZIF scientist Prof. Stephan Urban from the Heidelberg University @uniheidelberg.bsky.social will talk about the drug Bulevirtide, the first approved treatment for hepatitis D.

How are non-infectious HIV-1 particles converted to mature, fully infectious particles after release of virus particles? Find out more in this publication by the @briggsgroup.bsky.social together with scientists at @ciid-heidelberg.bsky.social!

Looking forward to teaching a @kakape.bsky.social inspired bridging seminar with Nora Heinzelmann on different aspects of modern biotechnology @marsilius.bsky.social. Looking forward to an interesting rollercoaster of opinions.

New paper in @biophysj.bsky.social led by @pintupatra.bsky.social on the analysis of two-color superresolution microscopy data, with an application to malaria-infected red blood cells. Collaboration with Lanzer lab in #SFB1129

#Measles can be fatal. Do you know its symptoms? 🔸 Rash that starts on the face and spreads over the body 🔸 Fever 🔸 Runny nose 🔸 Cough 🔸 Red and watery eyes 🔸 Small white spots inside the cheeks Seek health care if you suspect you or your child has measles.

Congrats Dr Annika Binder for a fantastic thesis and defense on microtubule binding proteins of #malaria #parasites exactly 25 years after I got my Dr for something with #actin and poxviruses and almost failed a question on, well, microtubule binding proteins.

Are you an internationally-minded researcher? We just opened the 2025 call for Marie Skłodowska-Curie Actions Staff Exchanges: 🔹 12-month secondments for knowledge & skills exchange 🔹 €97.7 million for some 85 research projects 🔹 International collaboration in innovation Apply by 8 October!

In der Debatte über die Corona-Pandemie kommt es zu zunehmenden Verzerrungen von Fakten und zeitlich-inhaltlichen Bezügen, v.a. hinsichtlich der "Maßnahmen" und Impfung. Die GfV verfasste nun ein Stellungnahme mit Anmerkungen zur Aufarbeitung der Pandemie in Deutschland: g-f-v.org/fuenf-jahre-...

Finally: Plasmodium actin filaments visualized in all their glory. Congrats Josie and Vojtech: www.embopress.org/doi/full/10....

After being named "breakthrough of the year" by Science magazine in 2024, the HIV drug lenacapavir continues to improve. New Phase I trials show the drug maintains protection for a full year after a single dose. buff.ly/9Q9QzET #ShareGoodNewsToo

Today is #WorldTBDay. #Tuberculosis - or TB - is caused by bacteria Mycobacterium tuberculosis that mainly affects the lungs. Common symptoms include ❗️ Cough ❗️ Chest pains ❗️ Weight loss ❗️ Fever ❗️ Night sweats Learn more about TB 👉 bit.ly/3yYNwzx #EndTB