Kidney transplant rejection linked to changes in lymphatic vessels Researchers found that when a kidney transplant is rejected, the lymphatic vessels around the transplanted kidney undergo changes, making it easier for the immune system to attack the new organ. www.ucl.ac.uk/news/2025/se...

Take a peek: This issue’s cover features 3D imaging and single-cell genomics by David A. Long @daniyaljafree.bsky.social & team, revealing lymphatic rewiring in kidney tissue with chronic transplant rejection: buff.ly/BZEw4az

Study pinpoints reason why transplanted kidneys can be rejected. Research by Prof David Long, @daniyaljafree.bsky.social (@uclchildhealth.bsky.social) and colleagues @greatormondst.bsky.social, Wellcome Sanger and University of Cambridge. bit.ly/47NIU1V @uclpophealthsci.bsky.social

An in-depth look at lymphatic reorganization! This issue’s cover features 3D imaging and single-cell genomics by David A. Long, @daniyaljafree.bsky.social & team, revealing lymphatic rewiring in kidney tissue with chronic transplant rejection: buff.ly/BZEw4az

🚨 New paper in @jclinical-invest.bsky.social! Kidney lymphatics are a promising target in transplant rejection 🗺️ In rejection, lymphatics expand and adversely remodel ⚡️ Although they have an anti-inflammatory profile, they are attacked by the immune system www.jci.org/articles/vie... 1/4

First of its kind study for children with arthritis reveals possible new disease targets. Researchers have been able to see what happens in the inflamed joints of children with arthritis, giving insight into why treatments affect children differently. Read: www.ucl.ac.uk/news/2025/ju...

I'll soon be advertising for a 3 year postdoc to join our lab at @edinuni-irr.bsky.social exploring #macrophages in salivary gland #development. Candidates should have a strong background in immunology/macrophage biology and/or developmental biology & key skills as below. Informal enquiries welcome!

Excited to share our new collaborative preprint between @uclnews.bsky.social and @sickkidsto.bsky.social 🥳 We found that kidney lymphatic vessels, an emerging target in kidney diseases, partly arises from the same group of cells that give rise to the kidney www.biorxiv.org/content/10.1... (1/4)

🧪 Job alert 🔊 we are hiring a Research Assistant - join the Simões Group at DPAG-IDRM @ox.ac.uk supporting #cardiovascular development and regeneration research, working with #zebrafish and #human stem cell systems: my.corehr.com/pls/uoxrecru... @oxforddpag.bsky.social @idrm.ox.ac.uk (1/4)

PhD position available in our team @dublincityuni.bsky.social from September. Please share/ contact me for informal enquiries.

For #FluorescenceFriday I'm sharing the fantastic work of postdoc Sarah McLarnon! A follow up to our '23 Development paper where we asked: Does precise vascular patterning matter for function and what happens after ischemic injury? The results were surprising! journals.physiology.org/doi/full/10....

Thrilled to share our new work in Nature Communications! We discovered how methionine → SAM → METTL3 → RNA methylation axis guides kidney development, especially nephron progenitor differentiation. #Nephrology #Epitranscriptomics Here’s a quick breakdown www.nature.com/articles/s41...

Delighted to be a Accelerator Award recipient @wellcometrust.bsky.social 🥳 I’ll work at @uclnews.bsky.social + @sangerinstitute.bsky.social, diving into how lymphatic vessels regulate immunity, whilst building clinical experience at @greatormondst.bsky.social wellcome.org/grant-fundin... (1/4)

Thrilled to share a new paper from my PhD in David Long’s lab at UCL, published in the Disease Models & Mechanisms journal! doi.org/10.1242/dmm.... We studied kidney microvasculature in polycystic kidney disease (PKD), the most common genetic cause of kidney failure (1/5)