🙏 Honored to receive the Breakthrough Article designation & grateful for the swift, rigorous, and highly professional peer-review process.

🧬 In #ADPKD, reduced PKD1 drives cyst growth and kidney failure. We previously discovered a 55bp cis-repressive element in its 3'UTR. We now identify the six critical bases—the miR-17 motif—whose disruption or masking restores PKD1 and slows disease

It was a pleasure to write this commentary. Thank you for the invite @jclinical-invest.bsky.social

Thrilled to share our new work in Nature Communications! We discovered how methionine → SAM → METTL3 → RNA methylation axis guides kidney development, especially nephron progenitor differentiation. #Nephrology #Epitranscriptomics Here’s a quick breakdown www.nature.com/articles/s41...

Texas fall evening....beautiful Lake Grapevine