Developed in direct response to NC3Rs recommendations, new guidance from the World Health Organisation (@who.int) encourages manufacturers and regulators to replace or remove animal-based quality control methods for vaccines and biologics: nc3rs.org.uk/news/new-who...

Looking for support to teach experimental design? Join our online workshop with @ukrepro.bsky.social on using the Experimental Design Assistant (EDA) to plan rigorous, reproducible animal studies. 📅 13 November, 10.00 – 16.00 (GMT) ❗ Registration closes: 17 September 👉 nc3rs.org.uk/events/ukrn-...

At the @nc3rs.bsky.social Prize ceremony and hearing about YCharOS- stonkingly high percentage of commercial antibodies don't work in applications for which they are recommended 😬

ARRIVE 2.0 turns five! Since we launched our updated guidelines in July 2020, we have developed a suite of resources to embed transparency and reproducibility throughout the research lifecycle, from planning to peer review: arriveguidelines.org/resources

So glad to be back in Hong Kong! 🇭🇰 Now let the marathon week begin, we will be presenting seven @nc3rs.bsky.social talks and workshops over four days. I’m especially looking forward to the HKLASS symposium hklass.org

📢 Free seminar by @bihatcharite.bsky.social on 𝐉𝐮𝐧𝐞 𝟏𝟕! Dr. Nikki Osborne ( @rrr-research.bsky.social) & Dr. ‪ @nathalie-pds.bsky.social (‪@nc3rs.bsky.social) will share tools for responsible & robust preclinical research. 🔗 bihealth.org/de/translati... #OpenScience #NC3Rs #PreclinicalResearch

Amazing account of ChatGPT's sycophancy and confabulation on steroids. amandaguinzburg.substack.com/p/diabolus-e...

Great to see this publication optimising a hydrogel-based model of cartilage. This approach has the potential to become a scalable platform to investigate biomechanical responses and replace mice in studies of musculoskeletal disease progression and ageing. Learn more: nc3rs.org.uk/our-portfoli...

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

SURVEY: New approach methodologies in safety assessment Are you involved in the development and application of replacement technologies for toxicity testing or submission and assessment of data for regulatory decision making? Help shape our plans for the coming years: nc3rs.org.uk/our-portfoli...

🔬 Transparent animal research is ethical, reproducible, and credible. Want to improve your lab's practices? Follow this 🧵 on the 10 essentials from the 𝐀𝐑𝐑𝐈𝐕𝐄 𝐆𝐮𝐢𝐝𝐞𝐥𝐢𝐧𝐞𝐬 #AnimalResearch #Transparency #ARRIVEguidelines #aRukon

This is a really good explainer about sex, gender and biology. It gives a clear account of the complexity and richness of differences.

💡 If you are an educator, science communicator or researcher involved in public engagement, this card game from @comeflywithjo.bsky.social can help you talk about how scientists choose the right biological model for their experiments and options to replace animal use.

"Estimating the replicability of Brazilian biomedical science" For 97 replications of 47 original experiments, 94% of replications were smaller effects than originals, and success rates ranged from 13% to 45% depending on the criterion. Incredible effort! Paper: www.biorxiv.org/content/10.1...

NEW | Analysing a story about an academic and smartphone bans… THE ANATOMY OF A SMEAR Comparing two news stories about an academic's view on school smartphone bans reveals just how easy it is to twist the narrative. brokenbottleboy.substack.com/p/4-the-anat...

The EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) have joined two of our CRACK IT projects as Challenge Partners, bringing their experience in validating new approach methodologies to help bridge the gap between innovation and market adoption: nc3rs.org.uk/news/eurl-ec...

Register for our NAMs Network symposium to connect with developers and end-users of new approach methodologies and join the discussion about reducing the reliance on animals for toxicity testing. 🗓️ Thursday 1 May, 9.30 – 17.00 📍 London, UK 👉 nc3rs.org.uk/events/nc3rs...

🔬✨ Interested in research transparency & reproducibility? Join the Meta-Science Summer School: design & launch a meta-research study! ➡️ Co-org. @germanrepro.bsky.social 📅 Date: 15-20 June 2025; apply by March 21! 🔗 www.bihealth.org/en/notices/m... #OpenScience #Reproducibility #MetaResearch (lmf)

A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.” Absurd we still need to go through this 🧪👩‍🔬

dnschecker.org#A/pubmed.ncb... They're removing it from DNS. You can currently get to it using the IP address 34.107.134.59 (add it to your hosts file or local DNS server), but like with USAID it's probably just a matter of time until it's gone unless they're forced to restore it. #pubmed

Pubmed is currently still working for me but not sure how long this will hold. Here is @hildabast.bsky.social ‘s blog post on what to do if Pubmed becomes unreliable absolutelymaybe.plos.org/2025/02/14/w...

THREAD Things that didn't make the news that will likely change our lives for the better The news is not an accurate reflection of the world. Good news doesn't get reported as much. Here are the wonderful things researchers have achieved recently. 1/24

If your research focuses on infection or immunity join us in two weeks to stay updated on non-animal approaches in the field, including organoids, human cell-based assays and virtual twins. 🦠 Register for the webinar: nc3rs.org.uk/events/non-a... 📅 Wednesday 26 February, 13.00 (GMT)/14.00 (CET)

#LoveMethods25 is coming in two weeks. 🔬 Love Methods Week 2025 – Putting Methods like #RRID in the Spotlight! ❤️ ✅ Document your methods with precision – to maximize reusability, transparency, and visibility ➡ Choose from 17 different session and register here: www.bihealth.org/de/aktuell/l...

An open letter to the President of the @royalsociety.org – time to stand up for your values. occamstypewriter.org/scurry/2025/...

To help you connect with us and each other, we've created a Starter Pack of UK Reproducibility Network people and affiliated organisation on BlueSky: #AcademicSky #OpenResearch #Research

NASA did a feature on me last year. It was up this weekend but now when you click on the link you get a 404 message.

I#LoveMethodsWeek25 is happening this year! We are hosting a workshop! Sign up for our workshop here: https://buff.ly/40SG1Jn Check out other events here: https://buff.ly/40Axc5u

⏰ The CRACK IT open call for 3Rs Challenges closes on Monday 10 February. If your organisation is facing a scientific or research challenge that could be solved with a 3Rs approach, get in touch to discuss and submit your idea to sponsor a Challenge. 💡 Find out more: nc3rs.org.uk/crackit/news...

"Most institutions judge their own researchers, leading to major conflicts of interest, and whistleblowers are often the ones who suffer the most" - interesting interview from Noémie Berroir (TheMetaNews) with @deevybee.bsky.social themeta.news/dorothy-bish...

This is very exciting, brilliant to see all these great initiatives and organisations brought together in one journal! lifecyclejournal.org/evaluation-s...

Really nice blog post on teaching experimental design to undergrads using the @nc3rs.bsky.social EDA - sounds like a really imaginative way of using a great tool! nc3rs.org.uk/news/teachin...

As we celebrate 20 years of the NC3Rs this year, 20,000 scientists are now using the Experimental Design Assistant (EDA) to design more rigorous in vivo studies and improve the reproducibility of animal research. Why not join them? eda.nc3rs.org.uk

Our Experimental Design Assistant tool helps researchers at any level design robust in vivo experiments. We have updated the report generated by the system to include all the methodological information required in the ARRIVE Essential 10 checklist: eda.nc3rs.org.uk/experimental...

We developed a simple mouse glucose tolerance test protocol for diabetes research with voluntary oral glucose dosing instead of gavage. More physiological/aligned to the human test & better for animal welfare 👇🏻 www.biorxiv.org/content/10.1... Please DM for detailed info or to arrange a chat