Thrilled to share! 🧬🌍 Our 800M+ long-read RNA-seq dataset from 8 diverse populations reveals big gaps in gene annotations for non-European transcripts. Let’s build global inclusive annotations. @bsc-cns.bsky.social @crg.eu @melelab.bsky.social www.nature.com/articles/s41...

El mapa de los genes humanos tiene un ‘agujero negro’: “Hemos dejado fuera a gran parte de la humanidad”

Human gene maps contain major blind spots that leaves out a vast majority of the world's biological diversity, according to a new study led by the CRG's @rodericguigo.bsky.social with @bsc-cns.bsky.social. The researchers uncovered tens of thousands of new transcripts and entirely new genes.

📣 Yesterday our study uncovering the ancestry bias in gene annotations was finally published in @natcomms.nature.com! www.nature.com/articles/s41... If you work in human genetics or transcriptomics, do not miss our tweetorial!👇 @guigolab.bsky.social @bsc-cns.bsky.social @crg.eu

the @melelab.bsky.social is hiring postdoctoral researchers !! come and work with us in sunny Barcelona!! auspire.eu/research-tea...

📣 We are hiring postdoctoral researchers!! Come and work with our wonderful team in sunny Barcelona. 👇 auspire.eu/research-tea...

📢Menopause affects half the population — yet it's been one of the most overlooked areas in aging research. We found that aging in the female reproductive system unfolds in unexpected, organ-specific ways. 🔗 www.biorxiv.org/content/10.1... 1/8🧵

Our lab had dual presence at #BoG25 @cshlmeetings.bsky.social! 🧬 Silvia González-López spoke on chromatin dynamics & transcriptional regulation. 🌍 @fairlie.bsky.social presented ancestry-aware gene annotations — a @guigolab.bsky.social × @melelab.bsky.social collab: www.biorxiv.org/content/10.1...

Excited to share our new preprint: The impact of sex, age, and genetic ancestry on DNA methylation across tissues. Briefly, we explored how sex, age, and genetic ancestry shape DNA methylation across tissues and individuals. Want to know a bit more? Follow this “bluetorial”! doi.org/10.1101/2025...

Do you work in 💫human genetics💫? Have you ever worried about what’s inside your gene annotation GTF⁉️ WELL, YOU SHOULD! 😱 Especially when studying a genetically diverse 🌍 cohort! 🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses! Don't miss this thread🧵⬇️ 1/13

Really interesting talk by our talented PhD student @mariasopenarios.bsky.social at #WomensHealth2025 conference!

AMAZING JOB by our postdoc Oleksandra presenting her results at #WomensHealth2025