Xuhui Huang (@xuhuihuangchem.bsky.social)

Our perspective on using computational tools to design bacterial RNA polymerase inhibitors is out in the "Computational Biochemistry" special issue of ACS Biochemistry. Congratulations to Eshani! pubs.acs.org/doi/full/10....

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Targeting Bacterial RNA Polymerase: Harnessing Simulations and Machine Learning to Design Inhibitors for Drug-Resistant Pathogens The increase in antimicrobial resistance presents a major challenge in treating bacterial infections, underscoring the need for innovative drug discovery approaches and novel inhibitors. Bacterial RNA... https://pubs.acs.org/doi/full/10.1021/acs.biochem.4c00751#