Great new work led by Aaron Kwok from @davisjmcc.bsky.social’s group. A tool to “denoise” contaminating transcripts from image based spatial data. www.biorxiv.org/content/10.1...

Check out @saahimall.bsky.social's #skysplain of our latest work! Very proud of all her hard work on this study and REALLY excited for what she's got planned next! #bpd #lungdevelopment #genomics #science

Our work looking at the effects of using autosomal assumptions for calling variation on X and Y. We used simulated data to compare to a ground truth. Tldr: Accurate ploidy is important for reducing false positives; appropriate alignment reduces false negatives. www.biorxiv.org/content/10.1...

America don't let up now. Preserve the NIH funding that lets us train the next generation of scientists and researchers! Carl Sagan would have said the same! bsky.app/profile/saga...

Excited to share our new work exploring strategies to overcome resistance to CAR T cell therapy in solid tumors. Using scRNA-seq, mouse models, and functional studies, our work points to SPP1 signaling in the TME as a critical component of this resistance. www.biorxiv.org/content/10.1...

Excited to share Ruqian has developed a package for this transcript based niche analysis. Check out the preprint and the package! This is a flexible approach and we're working on extending this for other spatial analyses! @davisjmcc.bsky.social www.biorxiv.org/content/10.1...

Today is World Tuberculosis Day. This year's theme is "We can end TB: Commit, Invest, Deliver." Our very own @ats-pitb.bsky.social works to help learn more and work to ending this disease!

Excited to post my first #skySplain about our recent work published yesterday in Nature Genetics! www.nature.com/articles/s41.... One of the first authors of this study - Annika Vannan – actually wrote this breakdown, but she's not yet over here on bluesky and asked me to post!

It’s been hard lately to focus on doing my job as a postdoc, which is under daily threat at this point. But we are persisting. Out now: “Dissociating the incubation of appetitive and consummatory behavior in a model of oral cocaine self-administration”. Very thankful to all who helped get this done!

It's not every day your work is on the cover of a magazine. Congrats to first author and TGen post-doc, @annikavannan.bsky.social, @nebanovich.bsky.social, his team and collaborators on earning the cover of this month's publication of @naturegenet.bsky.social 🧬 🫁 👏 Photo courtesy of Nature Genetics

The March issue of @naturegenet.bsky.social is live! Featuring: ✅spatial transcriptomics in pulmonary fibrosis ✅clonal hematopoiesis ✅psychiatric disorders across sex ✅PD-L1 succinylation in melanoma ✅human microglia isoform atlas ✅genomic analyses in Citrus & more ⬇️ www.nature.com/ng/volumes/5...

I am excited to share our most recent work using spatial transcriptomics to uncover dynamic molecular responses to rejection in transplanted human hearts! 1/15 www.biorxiv.org/content/10.1...

🎙️ Just published a new episode of Out of the Blue: An AJRCCM Podcast: Progressive Early Interstitial Lung Abnormalities in Persons At-Risk for Familial Pulmonary Fibrosis: A Prospective Cohort Study and Big Things Have Small Beginnings: Clinical Implications of Early Interstitial.... Have a listen:

@nebanovich.bsky.social recently partnered with Illumina to use its newest technology to uncover breakthroughs in spatial transcriptomics. The team was able to explore pulmonary fibrosis at a high resolution and uncover new mechanisms of the disease. More at: www.genengnews.com/topics/omics...