Annika Vannan
@annikavannan.bsky.social
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Postdoc
@tgenresearch.bsky
.social in the Banovich lab
reposted by
Annika Vannan
Nick Banovich
4 months ago
Check out
@saahimall.bsky.social
's
#skysplain
of our latest work! Very proud of all her hard work on this study and REALLY excited for what she's got planned next!
#bpd
#lungdevelopment
#genomics
#science
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Annika Vannan
Melissa Wilson
5 months ago
Our work looking at the effects of using autosomal assumptions for calling variation on X and Y. We used simulated data to compare to a ground truth. Tldr: Accurate ploidy is important for reducing false positives; appropriate alignment reduces false negatives.
www.biorxiv.org/content/10.1...
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Best practices for improving alignment and variant calling on human sex chromosomes
Sex chromosome complement is the largest karyotypic variation observed in humans. X and Y chromosomes were once a pair of homologous autosomes. Although chromosome X and Y differentiated from one anot...
https://www.biorxiv.org/content/10.1101/2025.04.29.651297v1
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Annika Vannan
Darrell Kotton
5 months ago
America don't let up now. Preserve the NIH funding that lets us train the next generation of scientists and researchers! Carl Sagan would have said the same!
bsky.app/profile/saga...
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Annika Vannan
Nick Banovich
6 months ago
Excited to share our new work exploring strategies to overcome resistance to CAR T cell therapy in solid tumors. Using scRNA-seq, mouse models, and functional studies, our work points to SPP1 signaling in the TME as a critical component of this resistance.
www.biorxiv.org/content/10.1...
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https://www.biorxiv.org/content/10.1101/2025.04.01.646202v1
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Annika Vannan
Nick Banovich
6 months ago
Excited to share Ruqian has developed a package for this transcript based niche analysis. Check out the preprint and the package! This is a flexible approach and we're working on extending this for other spatial analyses!
@davisjmcc.bsky.social
www.biorxiv.org/content/10.1...
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Annika Vannan
ATS Assemblies
6 months ago
Today is World Tuberculosis Day. This year's theme is "We can end TB: Commit, Invest, Deliver." Our very own
@ats-pitb.bsky.social
works to help learn more and work to ending this disease!
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Annika Vannan
Nick Banovich
8 months ago
Excited to post my first
#skySplain
about our recent work published yesterday in Nature Genetics!
www.nature.com/articles/s41...
. One of the first authors of this study - Annika Vannan – actually wrote this breakdown, but she's not yet over here on bluesky and asked me to post!
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Spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis - Nature Genetics
Xenium spatial transcriptomic profiling of pulmonary fibrosis characterizes cell composition dynamics and histopathological features associated with the disease.
https://www.nature.com/articles/s41588-025-02080-x
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Annika Vannan
Mark Namba, PhD
8 months ago
It’s been hard lately to focus on doing my job as a postdoc, which is under daily threat at this point. But we are persisting. Out now: “Dissociating the incubation of appetitive and consummatory behavior in a model of oral cocaine self-administration”. Very thankful to all who helped get this done!
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https://www.biorxiv.org/content/10.1101/2025.02.12.637922v1
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Annika Vannan
TGen
6 months ago
It's not every day your work is on the cover of a magazine. Congrats to first author and TGen post-doc,
@annikavannan.bsky.social
,
@nebanovich.bsky.social
, his team and collaborators on earning the cover of this month's publication of
@naturegenet.bsky.social
🧬 🫁 👏 Photo courtesy of Nature Genetics
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Annika Vannan
Nature Genetics
7 months ago
The March issue of
@naturegenet.bsky.social
is live! Featuring: ✅spatial transcriptomics in pulmonary fibrosis ✅clonal hematopoiesis ✅psychiatric disorders across sex ✅PD-L1 succinylation in melanoma ✅human microglia isoform atlas ✅genomic analyses in Citrus & more ⬇️
www.nature.com/ng/volumes/5...
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Annika Vannan
Angela Oill
7 months ago
I am excited to share our most recent work using spatial transcriptomics to uncover dynamic molecular responses to rejection in transplanted human hearts! 1/15
www.biorxiv.org/content/10.1...
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Dynamic responses to rejection in the transplanted human heart revealed through spatial transcriptomics
Allograft rejection following solid-organ transplantation is a major cause of graft dysfunction and mortality. Current approaches to diagnosis rely on histology, which exhibits wide diagnostic variabi...
https://www.biorxiv.org/content/10.1101/2025.02.28.640852v1
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Annika Vannan
ATS Blue Journal
7 months ago
🎙️ Just published a new episode of Out of the Blue: An AJRCCM Podcast: Progressive Early Interstitial Lung Abnormalities in Persons At-Risk for Familial Pulmonary Fibrosis: A Prospective Cohort Study and Big Things Have Small Beginnings: Clinical Implications of Early Interstitial.... Have a listen:
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Progressive Early Interstitial Lung Abnormalities in Persons At-Risk for Familial Pulmonary Fibrosis: A Prospective Cohort Study and Big Things Have Small Beginnings: Clinical Implications of Early Interstitial Lung Disease
Dr. Mohleen Kang chats with Dr. Margaret Salisbury and Dr. Anna...
https://share.transistor.fm/s/ba99effd
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Annika Vannan
TGen
7 months ago
@nebanovich.bsky.social
recently partnered with Illumina to use its newest technology to uncover breakthroughs in spatial transcriptomics. The team was able to explore pulmonary fibrosis at a high resolution and uncover new mechanisms of the disease. More at:
www.genengnews.com/topics/omics...
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Illumina Unveils Spatial Technology Days Before AGBT Meeting
Illumina announces a new NGS-based spatial technology kit and new software platform, Illumina Connected Multiomics.
https://www.genengnews.com/topics/omics/illumina-unveils-spatial-technology-days-before-agbt-meeting/
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