Angela Oill
@angela-oill.bsky.social
π€ 23
π₯ 49
π 15
Computational Scientist at the Translational Genomics Research Institute
reposted by
Angela Oill
Science Magazine
3 months ago
Pastoralism remains central to survival in the Turkana of northwest Kenya, where heat and water scarcity pose constant challenges. New research uncovers the genetic signatures that underlie adaptation to arid living in this pastoralist community. Learn more this week:
https://scim.ag/4nxcJbx
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reposted by
Angela Oill
Nick Banovich
4 months ago
So excited to share
@saahimall.bsky.social
just had her her first 1st author publication published in AJP lung! Huge accomplishment!!! This study wouldn't have been possible without the amazing
@jensucre.bsky.social
!
journals.physiology.org/doi/abs/10.1...
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A spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity | American Journal of Physiology-Lung Cellular and Molecular Physiology | American Physiological So...
A molecular understanding of lung organogenesis requires delineation of the timing and regulation of the cellular transitions that ultimately form and support a surface capable of gas exchange. While ...
https://journals.physiology.org/doi/abs/10.1152/ajplung.00191.2025
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Angela Oill
Saahithi Mallapragada
6 months ago
I am so excited to share our most recent work & my first big project as a graduate student! We leveraged spatial transcriptomics to study the cell-cell communication involved in human lung development. Hereβs the full study:
www.biorxiv.org/content/10.1...
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A spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity
A molecular understanding of lung organogenesis requires delineation of the timing and regulation of the cellular transitions that ultimately form and support a surface capable of gas exchange. While ...
https://www.biorxiv.org/content/10.1101/2025.06.02.656433v1
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Angela Oill
Nick Banovich
6 months ago
Congrats to
@saahimall.bsky.social
on her first study from her PhD! Also, science is always more fun when done with friends. Great to work as always with
@jensucre.bsky.social
and
@jkropski.bsky.social
!
add a skeleton here at some point
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reposted by
Angela Oill
Melissa Wilson
7 months ago
Our work looking at the effects of using autosomal assumptions for calling variation on X and Y. We used simulated data to compare to a ground truth. Tldr: Accurate ploidy is important for reducing false positives; appropriate alignment reduces false negatives.
www.biorxiv.org/content/10.1...
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Best practices for improving alignment and variant calling on human sex chromosomes
Sex chromosome complement is the largest karyotypic variation observed in humans. X and Y chromosomes were once a pair of homologous autosomes. Although chromosome X and Y differentiated from one anot...
https://www.biorxiv.org/content/10.1101/2025.04.29.651297v1
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reposted by
Angela Oill
bioRxiv Genomics
8 months ago
Best practices for improving alignment and variant calling on human sex chromosomes
https://www.biorxiv.org/content/10.1101/2025.04.29.651297v1
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Angela Oill
TGen
9 months ago
Ever wondered if there was a way to know if an individual would accept or reject a transplant organ? In this preprint,
@nebanovich.bsky.social
used spatial transcriptomics to study heart transplant rejection. Check out the story from GenomeWeb & the preprint!
www.genomeweb.com/gene-express...
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I am excited to share our most recent work using spatial transcriptomics to uncover dynamic molecular responses to rejection in transplanted human hearts! 1/15
www.biorxiv.org/content/10.1...
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Dynamic responses to rejection in the transplanted human heart revealed through spatial transcriptomics
Allograft rejection following solid-organ transplantation is a major cause of graft dysfunction and mortality. Current approaches to diagnosis rely on histology, which exhibits wide diagnostic variabi...
https://www.biorxiv.org/content/10.1101/2025.02.28.640852v1
9 months ago
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