Joe Sneath Thompson
@jsneaththompson.bsky.social
📤 11
📥 11
📝 0
reposted by
Joe Sneath Thompson
Barbara Hernando
2 months ago
This project has been with me since day 1 in the lab - a long journey of challenges, growth & incredible teamwork 🚀 So proud of
@gmaci.bsky.social
team for pushing this work to the finish line! Thks to collaborators (#Barbacid &
#FSanchezVega
labs) and
@caixaresearch.bsky.social
for their support
0
2
1
reposted by
Joe Sneath Thompson
Barbara Hernando
2 months ago
📢 New preprint out! We are thrilled to introduce our framework to track
#ongoingCIN
by leveraging single-cell genomics and CIN signatures:
www.biorxiv.org/content/10.1...
loading . . .
Tracking ongoing chromosomal instability using single-cell whole-genome sequencing
Chromosomal instability (CIN) generates aneuploid genomes that are characteristic of most cancers. While bulk genome sequencing reveals historical CIN, it lacks the resolution to identify ongoing CIN ...
https://www.biorxiv.org/content/10.1101/2025.11.26.690781v1
2
16
6
reposted by
Joe Sneath Thompson
8 months ago
The paper is published in
@natgenet.nature.com
. First authors:
@bhernando.bsky.social
,
@jsneaththompson.bsky.social
and Laura Madrid. With collaborations from Tailor Bio and
@cam.ac.uk
. Funding:
@saludisciii.bsky.social
@cienciagob.bsky.social
@cruk-ci.bsky.social
y
@lacaixa.bsky.social
1
2
2
reposted by
Joe Sneath Thompson
Cancer Research UK Cambridge Institute
8 months ago
The days of one-size-fits-all chemotherapy are ending. Researchers at our Institute,
@cniostopcancer.bsky.social
& Tailor Bio have developed a test that predicts resistance to common chemo drugs — paving the way for personalised cancer treatment. Find out more 👉
www.cruk.cam.ac.uk/news/scienti...
0
3
4
reposted by
Joe Sneath Thompson
Nature Genetics
8 months ago
📢OUT TODAY
@natgenet.nature.com
📰Predicting resistance to chemotherapy using chromosomal instability signatures. By
@jsneaththompson.bsky.social
,
@gmaci.bsky.social
and colleagues. ⬇️
www.nature.com/articles/s41...
add a skeleton here at some point
0
6
3
reposted by
Joe Sneath Thompson
Geoff Macintyre
8 months ago
🚨Chemo treatment upgrade!🚨 Check out our approach to modernise chemotherapy treatment published today in
@natgenet.nature.com
. From
@cniostopcancer.bsky.social
#TailorBio
@cruk-ci.bsky.social
www.nature.com/articles/s41...
More details 👇
loading . . .
https://www.nature.com/articles/s41588-025-02233-y
1
16
11
you reached the end!!
feeds!
log in