Flu vaccination does more than protect against viruses circulating that year. Our study published in #ScienceTranslationalMedicine showed historic 1994 vaccine generated broad immune responses against future H1N1 & FluB strains, but not H3N2, spanning 30 years. www.science.org/doi/10.1126/...

IFN-gene signatures in #Bcells following #influenza A and B virus infection and influenza #vaccination 👉 doi.org/10.1038/s44321-026-00395-8 By W. Zhang, @katherinekedz.bsky.social , T. Nguyen & colleagues @unimelb.edu.au @thedohertyinst.bsky.social

High expression of IL-18 receptor alpha correlates with severe respiratory viral disease and defines T cells with reduced cytotoxic signatures www.nature.com/articles/s41... @natcomms.nature.com @katherinekedz.bsky.social @thedohertyinst.bsky.social @unimelb.bsky.social

Who is vulnerable to a breakthrough infection after Covid mRNA vaccination? Especially those with rapid decline of antibodies or low spike-specific IgA titers early after a booster www.science.org/doi/full/10....

🌌 BREAKING: Mars may have left us a message. #NASA’s Perseverance rover has discovered potential #biosignatures — clues that life may not be unique to Earth. 🔭🧪 “This is the closest we’ve come to recognizing that life on Earth is not unique.” 🔗 MORE: tinyurl.com/OurIslandUni... #Mars #Astrobiology

Why do some people get seriously ill while others don't? Our new study in @pnas.org investigated how a population of memory T cells influence #COVID severity Read the paper: go.unimelb.edu.au/4zkp Or our article here: go.unimelb.edu.au/2zkp @katherinekedz.bsky.social @thedohertyinst.bsky.social

HLA-B*15:01 has been linked to protection from severe COVID, but this is not fool-proof. B*15+ individuals can still succumb to severe infections. Check out a recent study from Prof Kedzierska's lab 👇🏼 showing a lack of public TCR usage in B*15+ patients with severe COVID.

Central memory T cells with key TCR repertoires and gene expression profiles dominate influenza CD8+ T cell pools across the human lifespan @katherinekedz.bsky.social www.pnas.org/doi/10.1073/...

Thanks for the memories! Proud to have our study on central memory CD8+ T cells across the human lifespan published in PNAS today! You can read our paper: go.unimelb.edu.au/rp7p Or our article: go.unimelb.edu.au/jp7p @thedohertyinst.bsky.social‬ @cvandesandt.bsky.social‬ @katherinekedz.bsky.social‬