🧠Out now @natcomms.nature.com ! Brain changes linked to childhood maltreatment are among the field's most published findings. Yet, we find extensive replication failure of gray matter correlates in three large cohorts (N=3225), consistent across subsamples, models and operationalizations🧵

The CRC/TRR 393 aims to unravel trajectories of depression & bipolar disorder by combining mobile assessments, neuroimaging, -omics & interventions in >1500 participants. A 12-year effort to decode mechanisms of recurrence & remission. Overview: 🔗 rdcu.be/eGtBy

🥳 Our study led by @edwardody.bsky.social from the @tnm-lab.bsky.social is published in the European Journal of Neuroscience. Take a look if you are interested in action-perception transition, readiness potential, and voluntariness of action! 📍https://onlinelibrary.wiley.com/doi/10.1111/ejn.70236

Neural correlates of human fear conditioning and sources of variability in 2199 individuals www.nature.com/articles/s41...

🧠 New paper out! Rashid, Kircher & Straube (2025) investigate temporal characteristics of hemodynamic responses during active vs. passive hand movements in schizophrenia spectrum disorder. 📄 Schizophrenia: 👉 doi.org/10.1038/s415...

Kausalitätswahrnehmung, Erwartungen & psychische Gesundheit begeistern dich? Bewirb dich auf die Promotionsstelle (3 Jahre, 75%) in Marburg (www.theadaptivemind.de) bis zum 17.08.: stellenangebote.uni-marburg.de/jobposting/1... #Job #Promotion #fMRI #Psychologie

🧠🗣️ I’m co-editing a Neuropsychologia Special Issue: “Language in Psychosis – A Multidisciplinary Approach” We welcome contributions on: • neural mechanisms • predictive processing • cognitive, computational & clinical perspectives 📅 Deadline: Sept 30, 2025 www.sciencedirect.com/special-issu...

Delay adaptation does not transfer between discrete button press actions and continuous control - Loes CJ van Dam, Svenja Kernig, Karina Lazarova, Melisa Ünal, Nicole Gappa, Benjamin Straube, Thomas SA Wallis, 2025 journals.sagepub.com/doi/10.1177/... @tsawallis.bsky.social

Feeling excluded can distort your decisions! New study shows tDCS can buffer against the effects of social exclusion on decision-making. 🔗 academic.oup.com/scan/advance... #neuroscience #tDCS #socialexclusion #mentalhealth

New manuscript! Together with Junqing Huang & @straubeb.bsky.social, we used an innovative paradigm & DDM to show that gesture's processing hierarchy from a behavioral perspective! Gestures are visual—but they’re also layered, structured, and unfold like language. 🧠🖐️ 👇👇👇 osf.io/r5nb9_v1

The #ClustersOfExcellence have been selected: today, the Excellence Commission approved 70 projects for funding. 45 clusters will continue and 25 will be newly established. Funding starts on 1 Jan 2026 for 7 years, with €539 million per year. The full list: www.dfg.de/resource/blo... 1/3

🧠✨ New publication in Brain Communications! Schizophrenia spectrum disorders & motor preparation: Aberrant pre-movement fMRI patterns in insula, putamen, cerebellum & angular gyrus 🔗 doi.org/10.1093/brai... #Schizophrenia #fMRI #ActionAwareness #CognitiveNeuroscience #Psychiatry

🚨 New in Molecular Psychiatry 🚨 DNA methylation as a potential marker for anxiety disorders & psychotherapy response: Longitudinal EWAS reveals epigenetic signatures linked to disease risk and CBT outcomes. 📖 doi.org/10.1038/s413... #Anxiety #Epigenetics #CBT #Psychiatry #PrecisionMedicine

Join the #SFBTRR393 in Marburg! Two open PhD positions (65%) in A04, investigating inflection signals in #depression using MRI, EMA & EEG. You’re passionate about translational #psychiatry and want to work in an interdisciplinary environment? Apply by April 27 via the official portal ⬇️ #ResearchJob

How do patients with schizophrenia Spectrum Disorder perceive causality? We show altered reliance on spatial vs. temporal cues—and a growing bias to repeat prior choices over time. ➡️ doi.org/10.1038/s415... #Schizophrenia #Perception #Cognition #Neuroscience

And here the poster!

If you are at #CNS2025, check out this brilliant poster #F98 from @edwardody.bsky.social @straubeb.bsky.social where we probed for action-specific "quasi-predictive" effect independent of probability-based expectations!

Hi! We are the SFB/TRR 393 "Trajectories of Affective Disorders: Cognitive-Emotional Mechanisms of Symptom Change" - a transregional @dfg.de collaborative research center & interdisciplinary team of researchers working together to better understand what influences the course of affective disorders👇🏻🧵

Patients with schizophrenia spectrum disorders show reduced differentiation between self- and externally generated sensory input, particularly during tool use and bimodal feedback. 🔗Read more: www.nature.com/articles/s41... #Neuroimaging #Schizophrenia #PredictiveCoding #fMRI @cschmitter.bsky.social

New paper about “Predictive neural processing of self-generated hand and tool actions in patients with schizophrenia spectrum disorders” has been accepted for publication in Translational Psychiatry! Congratulations Christina Schmitter, C.V., Pazen, M., Uhlmann, U., van Kemenade, B.M., Kircher,…

#PLOSONE: Modelling sensory attenuation as Bayesian causal inference across two datasets dx.plos.org/10.1371/jour... Congratulations @eckertal.bsky.social

📢 Stellenausschreibung im TNM-Lab: Qualifizierungsstelle (65%) mit Promotionsziel im SFB/TRR 393 an der Philipps-Universität Marburg. Forschung zu affektiven Störungen mit modernster Ausstattung (MRT, EEG). Bewerbungsfrist: 02.02.2025. stellenangebote.uni-marburg.de/jobposting/f...

Advancing the personalized advantage index (PAI): a systematic review and application in two large multi-site samples in anxiety disorders | Psychological Medicine | Cambridge Core - www.cambridge.org/core/journal...

Proud to debut in BlueSky with a fascinating new preprint from @tnm-lab.bsky.social @straubeb.bsky.social led by Edd Ody, where we used MVPA of EEG to show how motor preparation and sensory perception are related in action-effect contingency. 🔗https://shorturl.at/XZp5q 🧵👇

🧵1) Participants made active (self-initiated) or passive (finger moved by electromagnet) movements triggering bimodal auditory/visual stimuli. They were followed, in a block-wise manner, by unimodal auditory/visual comparison stimuli, and participants judged which stimulus was brighter or louder.

🧵2) We looked at the EEG around the bimodal stimuli. Univariate ERP shows that RP differed between movements and task modalities, but did not show any interaction (A-B). Sensory VEP suggests a clear active suppression: the modality difference was reduced in the active movement.

🧵3) We then decoded task modality. In motor preparation, active showed higher decoding accuracy than passive, suggesting enhance prediction. But in the perception time window, decoding accuracy was lower in the active condition, suggesting less difference between modalities (again suppression).

🧵4) We then did temporal generalization. Here, broadband EEG did not show pattern similarity between both time windows. But the neural pattern was similar when we looked at the alpha amplitude. By-subject correlation also suggests positive correlation between both windows in the alpha band.

🧵5) Our data thus shows that voluntary (vs. passive) movement shows enhanced prediction during motor preparation and suppressed neural processing of their sensory outcome (in terms of modality). Also, alpha oscillations may directly mediate motor preparation and sensory perception.

This review was fabulously led by Lukas Kirchner, with contributions by @maxberg91.bsky.social, @eckertal.bsky.social, @straubeb.bsky.social, and other Bluesky-less people. Thanks for the nice collaborative work!

Social expectations in depression Review by Lukas Kirchner, Tobias Kube, Max Berg, Anna-Lena Eckert, Benjamin Straube, Dominik Endres & Winfried Rief Web: go.nature.com/41kXLO1 PDF: rdcu.be/d2yHr #psychology #psychscisky #clinpsy

How do negative social expectations shape the onset, course, and severity of depression? Our review in @NatureRevPsych explores the cognitive and interpersonal mechanisms driving these processes, offering insights for intervention. Read it here: rdcu.be/d2ylD #Psychology #Depression #MentalHealth

Made a starter pack for researchers who are actively working on or have an interest in the cerebellum. DM me to be added or reply to this thread! 🧠🤏🏻 go.bsky.app/7X4ekSH #neuroscience #neuroskyence #cerebellum #neuroimaging #dbs #fmri

A starter pack of layer-fMRI folks here: go.bsky.app/TUWFNzg

BLUESKY MEGA-THREAD Altmetric is thrilled and also LITERALLY RELIEVED to officially announce: We are now tracking research attention as it happens on Bluesky! We have been picking up posts on the site since late Oct. Our team is on Bluesky all day answering questions. Let's get into it!