Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬 📄 www.biorxiv.org/content/10.1... 🌐 search.foldseek.com/folddisco

📢 Deadline Extended! The application deadline for the PhD student position has been extended to July 4th. If you haven’t applied yet, there’s still time! 👇

🚨 We're hiring a Bioinformatics Engineer! 🛠️ Develop #JuliaLang & Python tools to model structural and evolutionary features of IDPs 📅 Start: 1 Sept 2025 🎓 3+ years of higher education (Master’s or engineering diploma preferred) 👉 Apply now: emploi.cnrs.fr/Offres/CDD/U...

Great news! I’m hiring a PhD student in structural #Bioinformatics to work on modeling protein conformations and interactions at @i2bcparissaclay.bsky.social as part of the ANR SPPICES project! 🚀 📅 Start: 1 Sept 2025 ⏳ Deadline: 23 June 2025 👉Apply now: emploi.cnrs.fr/Offres/Docto...

AlphaFold is amazing but gives you static structures 🧊 In a fantastic teamwork, @mcagiada.bsky.social and @emilthomasen.bsky.social developed AF2χ to generate conformational ensembles representing side-chain dynamics using AF2 💃 Code: github.com/KULL-Centre/... Colab: github.com/matteo-cagia...

BioEmu is now easily accessible on Colab. Thank you @martinsteinegger.bsky.social and @jjimenezluna.bsky.social !! @msftresearch.bsky.social

@googlecolab.bsky.social now has native support for #JuliaLang! 🎉 No special setup is needed anymore—start coding and sharing your @julialang.org projects! 🚀

🚨 I am super happy to announce that our analysis of how the structure of protein-RNA interfaces evolves is now published (early access) at @plos.bsky.social Computational Biology: doi.org/10.1371/jour... 🧬🧶

Chai-1, the open source AF3 clone, is now available with an Apache 2 license github.com/chaidiscover...

Hey folks! I got a bit swamped with all the new #julialang BlueSky people and made my own mega Julia #programmer starter pack! go.bsky.app/Hv4RKzM What other starter packs would you want to see? I'm in health research, mathematics, and open source/science. 🧪🛟🩺 📊

New here? Interested in AI/ML? Check out these great starter packs! AI: go.bsky.app/SipA7it RL: go.bsky.app/3WPHcHg Women in AI: go.bsky.app/LaGDpqg NLP: go.bsky.app/SngwGeS AI and news: go.bsky.app/5sFqVNS You can also search all starter packs here: blueskydirectory.com/starter-pack...

This is the first fully open source release of a AF3 like model. Awesome! Congratulations to the team.

⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️ 🔄Share to help people finding its topic/field - STRUCTURAL BIOLOGY Structural Biology 1: bsky.app/starter-pack... Structural Biology 2: bsky.app/starter-pack... Crystallography: bsky.app/starter-pack... Synchrotron&CryoEM: bsky.app/starter-pack...

🎉 Exciting news! Our latest paper in Nature Communications delves into protein-protein interaction networks & IDRs using AlphaFold2. Dive into our findings here! 🧬 #Bioinformatics 1/8

Gonna stop curating structbio/ML preprint & papers for a few weeks. The colab notebook below should mostly do the trick (except arxiv) for anyone interested in catching up on whats going on colab.research.google.com/drive/17e0pD...

Happy to share our research on using AlphaFold2 to predict how peptides from disordered regions bind proteins, just published in NatureComms rdcu.be/dwlLa Work done with Hélène Bret and Raphael Guerois and for the revised version with great contributions from @diegozea.bsky.social and Jinmei Gao. 🧬🧶

New experiment: I will work on a project (starting question: what antibiotic resistance genes co-occur in genomes/metagenomes and does it matter?) completely in the open Everyone is welcome!

CASP16 will start later this year, so to celebrate that here is a short thread on the uncanny valley separating experimental structures & computational models of proteins. Even though the latter are extremely accurate, there are still some weird differences that are hard to pin down.  🧪🧶🧬🧵

My wish for 2024 is that all authors are this direct with their findings

Joris K. - Building Fast Packages Faster: #Julialang as a Backend to #Python and #R (#RStats) Using Julia instead of C or Fortran for package internals can have many advantages for Python and R users, since the language acts more similar to the higher level languages www.youtube.com/watch?v=JD8H...