New paper from the lab, where we demonstrate a new approach for producing #snakebite #antivenom using recombinant #nanobodies and low-cost microbial #biomanufacturing, out in Trends in Biotechnology. Read paper here: www.sciencedirect.com/science/arti...

New paper from the lab, where we demonstrate a new approach for detecting #toxins from #cholera and E. coli using point of care #diagnostic principles. Read paper here: pubs.rsc.org/en/content/a...

New research article from the lab on direct #protein #sequencing without genomic references, which is (normally) particularly challenging: www.mcponline.org/article/S153... Thanks to great co-authors and generous funders!

New review from the lab on large animal models used for studying #snakebite #envenoming and evaluating #therapeutic interventions: www.nature.com/articles/s44...

Excited to share our new study showing how combining consensus #allergens with intracellular delivery via #mRNA-LNP technology could help treat #allergy: www.nature.com/articles/s41... Led by Esperanza Rivera de Torre and a fantastic international team across academia and industry!

To those interested in watching my dr.techn. (higher doctorate) defense on #Engineering #Antivenom, but did not get the chance to see it live, here is the full lecture and Q&A: www.youtube.com/watch?v=xWA_...

Job opening in Y-king Biologics! We are looking for a Senior Scientist to help us develop pH-responsive antibodies for therapeutic purposes: bioinnovation-ac23af.careers.hibob.com/jobs/58efb9a... Y-king Biologics is a Bio Studio project at the BioInnovation Institute: bii.dk/community/st...

Thanks to Blake Forman for highlighting snakebite as a neglected tropical disease and my group’s research efforts towards developing better antivenoms: www.technologynetworks.com/biopharma/ar...

Exalted to announce that Bactolife has just secured over EUR 30 million from new and existing investors to commercialise and clinically validate our binding proteins! Press release: www.bactolife.com/bactolife-se...

New paper from the lab on how #virulence of human #pathogenic enterotoxigenic E. coli and V. cholerae can be attenuated using #binding #proteins: www.tandfonline.com/doi/full/10.... Thanks to great co-authors and funders!

For those that are interested, I am defending my dr.techn. dissertation (Engineering antivenom) on January the 23rd at 9.00-12.00 CET in meeting room 1 (first floor) at the Technical University of Denmark: dtu.dk/kalender/dok...

Rao, @andreaslaustsen.bsky.social et al. present a chromosome-level genome assembly of the western nose-horned viper. The 1.55 Gbp assembly (contig N50 = 45.9 Mb; scaffold N50 = 210 Mb; BUSCO = 97.1%) is anchored into 18 pseudo-chromosomes. 🔗 doi.org/10.1093/gbe/evaf210 #genome #evolution

Excited to announce that my dr.techn. (higher doctorate) dissertation #Engineering #Antivenom is now accepted for defence at the Technical University of Denmark and publicly available: orbit.dtu.dk/en/publicati...

Can #mRNA technology be used to treat #snakebite #envenoming? In this new paper, we explore the utility of mRNA-encoded #antibodies delivered using lipid nanoparticles to neutralise #snake #toxins. Read paper: www.sciencedirect.com/science/arti...

For the Danish speaking audience, @videnskab.dk has made a portrait of me and my research career so far, focusing mostly on my work on snakebite envenoming, but also a few other projects, including research done at Bactolife and VenomAid Diagnostics: videnskab.dk/naturvidensk...

Fantastic to see our article "Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites" on the cover of @nature.com, represented by a beautiful picture of the Eastern green mamba, taken by Prof. Wolfgang Wüster! Read article here: www.nature.com/articles/s41...

New paper from the lab, where we sequenced the genome of Europe's most venomous snake, Western nose-horned viper (Vipera ammodytes ammodytes)! Read paper in Genome Biology and Evolution: academic.oup.com/gbe/advance-...

While a new, broad-spectrum 'nanobody' antivenom performed impressively in preclinical trials, the real significance is “showing this is possible,” @andreaslaustsen.bsky.social told me. That and more of the best from @science.org and science in #ScienceAdviser: www.science.org/content/arti... 🧪

Excited to share a new paper led by @andreaslaustsen.bsky.social, Anne Ljungars, @tpjenkins.bsky.social, Shirin Ahmadi and Nick Burlet. It was a privelege to be a part of this amazing team! www.nature.com/articles/s41...

New article from the lab, where we describe how we developed a "Nanobody-based recombinant #antivenom for #cobra, #mamba, and #rinkhals bites" out in @nature.com!

New review article from the lab on "Advances in #antibody-based strategies for targeting #cancer-associated #glycopeptide antigens" just out in Drug Discovery Today, mainly written by my awesome PhD student, Edward Meier! Read paper: sciencedirect.com/science/arti...

For those understanding German that are interested in getting up to date with the world of #snakebite #antivenoms and research in this field, Brigitte Osterath has written a great article for @gdch.de: gdch.app/article/wenn... Full access: www.writingscience.de/artikel/schl...

I’m excited to share our new paper in mAbs! We engineered pH-dependent antibodies without histidine “doping,” showing the light chain controls pH sensitivity by modulating water access. Link: www.tandfonline.com/doi/full/10....

Excited to share the newest research paper from our lab, where we discover #nanobodies against #snake #neurotoxins using specially designed #consensus toxins and phage display technology. Link to paper in first comment.

New research article where we use consensus #toxins as #antigens for discovery of #nanobodies, showcasing this with short-chain alpha-neurotoxins from snakes - notoriously difficult to discover antibodies against. Read article here:https://www.tandfonline.com/doi/full/10.1080/19420862.2025.2522838

Thanks to Laura Tran for highlighting our work on Binding Proteins against cholera toxin: www.the-scientist.com/new-cholera-... Original research article: www.nature.com/articles/s41...

Happy to share this "Ubegribeligt" podcast episode (in Danish) on venom and antivenom, which I had the pleasure of doing together with Huxi Bach from Danmarks Radio: www.dr.dk/lyd/p1/ubegr... In the podcast, we discuss animal venoms, antivenom, and R&D, and spinout!

Pleased to share this new publication on the effects of Binding Proteins against virulence factors from enterotoxigenic E. coli: jasbsci.biomedcentral.com/articles/10.... As an #antibody engineer, I find it super interesting that we in this study show how stable #Binding #Proteins can be!

🚨 We’re hiring a PhD student! 🚨 Join us at DTU Bioengineering + collaborators Messoud & Håkan Ashina + Esperanza Rivera de Torre to bring preventative migraine therapeutics from 💻 to 🧠 🔗 Apply: lnkd.in/dCRU_EN3 🔍 Project: lnkd.in/dbpi8MwX

I co-wrote an opinion piece in a Danish newspaper. There are a few EU initiatives focused on recruiting american scientist. These ignore that the developments in the US the past years have spread here as well. We need a strategy and stronger political will, if we are to be a safe haven for science.

🚨 Big news! We’ve received a NovoNordisk Foundation Tandem Grant for #MIGRAINE — designing #AI-powered #GPCR-targeting biologics for chronic migraine. From computer to human in 4 years. Proud to team up with Messoud and Hakan Ashina, as well as Esperanza Rivera de Torre! 🧠 + 💊 + 🧬 = new hope.

I am grateful to the Technical University of Denmark (DTU) who kindly awarded me with the university's Innovation Award 2025 for my contributions to innovation, entrepreneurship, and spinout of companies. www.dtu.dk/nyheder/alle...

I shared thoughts with @statnews.com on new research aiming to develop a universal antivenom, using antibodies from Tim Friede’s decades of self-immunization. Thanks to @usha.bsky.social for including me in the scientific discussion. 🐍👇 www.statnews.com/2025/05/02/d...

I had the chance to comment on a new study in Cell about the development of human monoclonal antibodies for #snakebite treatments. Grateful to @nerdychristie.bsky.social & @science.org for including me in the scientific discussion! Fascinating work. 🐍👇 www.science.org/content/arti...

Our review article on progress towards #recombinant #antivenoms for #snakebite is now published at www.tandfonline.com/doi/full/10.... We cover snakebite, methods for #mAb discovery, do a deep dive on mAbs for neurotoxins, and discuss what is needed next to get this from concept to clinic.

New scientific article from the VenomAid Diagnostics in collaboration with the Center for Antibody Technologies at Danmarks Tekniske Universitet - DTU and Bactolife, led by our fantastic PhD student Selma Blom Belfakir! Read the article here: www.sciencedirect.com/science/arti...

Thanks to Henrik Reinberg Simonsen from Sundhedspolitisk Tidsskrift for the fun interview on what cultural experiences I enjoy and for putting a bit of focus on YATSI's competition Denmark's Best Science Meme: sundhedskultur.dk/kultur/905-v...

Thanks to Videnskab.dk for putting a bit of spotlight on our competition Denmark's Best Science Meme, which we have the pleasure of organizing in YATSI: videnskab.dk/kultur-samfu... If you like science and memes, make sure to submit your best science meme asap!

🎉 Big news! Our paper is out in Nature Machine Intelligence! "InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments" 🔗 www.nature.com/articles/s42... 👇 Thread 🧵

New AI tools InstaNovo and InstaNovo+ can now detect proteins previously beyond reach, opening doors in cancer research and disease biology. Early results are promising, though 5% may be false positives. 🧬💻

Eloff et al.’s InstaNovo uses transformers plus a diffusion refinement to perform high-throughput de novo peptide sequencing. It recovers more novel peptides at low FDR, outperforms current tools, and extends proteomics beyond database limits. www.nature.com/articles/s42...

Excited to share a new paper in Nature Machine Intelligence that I had the pleasure of contributing to, alongside great collaborators from Europe! InstaNovo is a deep learning model for de novo peptide sequencing — pushing proteomics beyond databases. 📄 www.nature.com/articles/s42...

Happy to announce that our preprint "De novo genome assembly of Vipera ammodytes ammodytes reveals venom gene expansion and ecological adaptations" is now online: researchsquare.com/article/rs-5... In this preprint we describe the genome of #Europe's most #venomous #snake!

I am very excited to announce the publication of this new research article on "Orally delivered toxin–binding protein protects against diarrhoea in a murine cholera model", which is a topic I sincerely care about: nature.com/articles/s41... Thanks to all co-authors and funders!

Thanks to Yrsa Bom Hansen from Science Report for the interview about what my favourite research tool is and why (spoiler alert: it is phage display): sciencereport.dk/kultur/andre... Thanks to John and Aneesh for teaching me how to discover human monoclonal antibodies!

Humbled to receive the Elite Research Prize, awarded by Queen Mary of Denmark & Minister Christina Egelund. This honor reflects the incredible work of my team and our collaborators! Read more: ufm.dk/forskning-og... More on my center: antibody.dk #EliteForsk

New publication, where I share my opinion on the prospects of recombinant #antivenoms reaching the clinic in the future. In Transactions of the Royal Society of Tropical Medicine and Hygiene: academic.oup.com/trstmh/advan...

Lige før jul havde jeg fornøjelsen af at deltage i denne podcast om min forskning inden for antistoffer, modgift og bioteknologi sammen med Anja C. Andersen og Mette Holbæk: podcasts.apple.com/dk/podcast/v... @villumfonden.bsky.social

Great read in @nature.com about how to write the best "cold e-mail" in job applications: www.nature.com/articles/d41... Thanks for including a few tips from me, such as: "If they’re not going to research my group, they’re probably not going to research other things very well either."

Happy to share a new article from the Center for Antibody Technologies at the Technical University of Denmark: journals.plos.org/plosntds/art... Together with great collaborators from the Liverpool School of Tropical Medicine and Bayero University, Kano, and with advice from international experts...