🧪🐍 AI vs venom! Our Nature paper with David Baker shows AI-designed proteins can block deadly snake toxins. Now featured by Reuters! 🎥 ✅ 80–100% survival in mice 💸 Cheap, fast, scalable 🌍 A step toward better antivenoms 📄 www.nature.com/articles/s41... 🎬 youtu.be/gnvEDMEr2mc

Thrilled to announce our paper, "De novo-designed pMHC binders facilitate T cell-mediated cytotoxicity toward cancer cells," is officially out in @science.org! We used generative AI to build a 'GPS' for immune cells to hunt cancer. Read it here: doi.org/10.1126/scie...

While I’m bouncing between emails and desperately waiting for my holiday, it’s good to know at least something in the lab is holding it together. Thermal stability might not be glamorous, but it’s underrated. Designerbodies: even when things get heated, still doing their job ;)

At AffinityAI we’re moving from “finders keepers” to “designers binders”, one generative model at a time. If you could have a binder to anything, what would it be? (Proteins, obscure signalling pathways, that one reviewer who never gets back to you…;)

Ægget redefined the lounge. We're redefining what it means to design a protein. At AffinityAI, we combine Danish design sensibilities with precision molecular engineering. Elegant. Efficient. Engineered to bind. 🧬 Discover how we’re reshaping molecular function: www.affinityai.bio

🎧 Had the pleasure of joining Anders Høeg Nissen on the AI Denmark Podcast to talk about how we’re using AI to crack the protein code 🧬 Catch my segment from 9:30 (and yes — it’s in English 😉) 🎙️ open.spotify.com/episode/4g3R...

Great to see #AffinityAI represented by Esperanza and Oliver at the DTU Startup Day 💪 Lots of interest in what we’re building, especially the fact that we deliver #real #reagents rather than just #AI predictions. Excited for what's to come!

🚨 We’re hiring a PhD student! 🚨 Join us at DTU Bioengineering + collaborators Messoud & Håkan Ashina + Esperanza Rivera de Torre to bring preventative migraine therapeutics from 💻 to 🧠 🔗 Apply: lnkd.in/dCRU_EN3 🔍 Project: lnkd.in/dbpi8MwX

🚨 Big news! We’ve received a NovoNordisk Foundation Tandem Grant for #MIGRAINE — designing #AI-powered #GPCR-targeting biologics for chronic migraine. From computer to human in 4 years. Proud to team up with Messoud and Hakan Ashina, as well as Esperanza Rivera de Torre! 🧠 + 💊 + 🧬 = new hope.

🚀 Big news: AffinityAI is live We’ve built a platform for custom protein binders, AI-designed, in vitro validated, and entirely animal-free. I'm proud to lead this as CEO. 🔗 affinityai.org #AffinityAI #Biotech #ProteinEngineering

1/ 🚀 InstaNovo just got a major upgrade. Our Nature Machine Intelligence paper with @instadeepai presents v0.1—but while the paper was under review, we kept building. Now releasing InstaNovo v1.1, with major gains. Blog: bit.ly/4lircYB 🧵

I am very excited to announce the publication of this new research article on "Orally delivered toxin–binding protein protects against diarrhoea in a murine cholera model", which is a topic I sincerely care about: nature.com/articles/s41... Thanks to all co-authors and funders!

Excited to share a new paper in Nature Machine Intelligence that I had the pleasure of contributing to, alongside great collaborators from Europe! InstaNovo is a deep learning model for de novo peptide sequencing — pushing proteomics beyond databases. 📄 www.nature.com/articles/s42...

Eloff et al.’s InstaNovo uses transformers plus a diffusion refinement to perform high-throughput de novo peptide sequencing. It recovers more novel peptides at low FDR, outperforms current tools, and extends proteomics beyond database limits. www.nature.com/articles/s42...

New AI tools InstaNovo and InstaNovo+ can now detect proteins previously beyond reach, opening doors in cancer research and disease biology. Early results are promising, though 5% may be false positives. 🧬💻

🎉 Big news! Our paper is out in Nature Machine Intelligence! "InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments" 🔗 www.nature.com/articles/s42... 👇 Thread 🧵

🚀 Tackling one of life science’s biggest challenges: AI-driven biologics design! Excited to lead #DTU’s collaboration with #NovoNordisk to build a closed-loop #AI platform for binder design & optimization. Even better? We’re hiring! 📢 6 open positions! 🎉 (1/5)

Nature research paper: De novo designed proteins neutralize lethal snake venom toxins https://go.nature.com/4fZU9EI

Deep learning methods aid in de novo design of proteins to neutralize lethal snake venom toxins in vitro and protect mice from a lethal neurotoxin challenge. www.nature.com/articles/s41... #NBThighlight

This pretty much settles it: we're entering the era of low-cost, on-demand binders for everything Excited to see what people build now that "inject a llama with some junk and bleed it a month later" is no longer the cutting-edge tech www.nature.com/articles/s41...

EXTREMELY cool and demonstrates clearly the promise of deep learning + bio. www.nature.com/articles/s41...

Loved talking to @tpjenkins.bsky.social about this work 🐍

🚨 Revolutionising Snakebite Treatments with AI-Designed Proteins 🐍 I'm proud to share our latest study published in hashtag#Nature, driven by Susana Vazquez Torres, and co-led by David Baker (Institute for Protein Design, University of Washington) and myself.

🎉Looking for an exciting opportunity in proteomics and data science?🎉 Join DTU Bioengineering as a #Data #Science Specialist in #Proteomics! Based at our state-of-the-art DTU Proteomics Core. You'll also collaborate with me and the DTU Bioengineering Data Science Hub. lnkd.in/d2zHaMys

🌟 Thrilled to announce that our project, Deep Immune Receptor Modeling (#DIRM), has been awarded funding under the (@novo-nordisk.bsky.social) Nordisk Foundation Data Science Collaborative Research Programme! 🎉

Last week, David Baker, alongside John Jumper and Demis Hassabis, received the #Nobel Prize in #Chemistry🏆. It was incredibly special to see our group's and collaborators' work highlighted in the Nobel speech, along with the vital issue of #snakebite #envenoming🎉.