Kevin Zhang
@kyzhang.bsky.social
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Neuropathology trainee @JHU studying brain metastasis with
@ashi-w.bsky.social
reposted by
Kevin Zhang
The Mark Foundation for Cancer Research
about 2 months ago
We're back from the
@theaacr.bsky.social
Special Conference on Early Onset Cancers! A major highlight was the update from Mark Foundation-Waxman Foundation grantee Ashani Weeraratna on her research into how the aging tumor immune microenvironment influences tumor progression.
#AACRearlyonset25
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reposted by
Kevin Zhang
Rimas Orentas
3 months ago
Are you using the right tumor micro environment model? Cancer is a disease of aging
@sitcancer.bsky.social
#SITC25
great session at the annual meeting on the aged immune system and the tumor micro environment moderated by Drs DA and A Weeraratna.
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reposted by
Kevin Zhang
Winkler Laboratory
4 months ago
How to disconnect therapy-resistant tumor networks in glioblastoma? In our paper, online @Cancer Discovery, we built an anti-tumor microtube (TM) screening pipeline and found that Protein Kinase C activators disrupt TMs, silence Ca²⁺ “pacemakers” and boost radiotherapy.
doi.org/10.1158/2159...
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reposted by
Kevin Zhang
Nature Reviews Cancer
5 months ago
Review 🚨 Easwaran&Weeraratna outline how
#ageing
leads to epigenetic alterations in the
#TME
, enhancing clonal expansion of mutations and ultimately increasing cancer risk. 📖 👇
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Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer - Nature Reviews Cancer
In this Review, Easwaran and Weeraratna outline how ageing leads to epigenetic alterations in the tissue microenvironment, enhancing clonal expansion of mutations and ultimately increasing cancer risk.
https://bit.ly/47FVoIR?utm_source=dlvr.it&utm_medium=bluesky
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www.cell.com/neuron/fullt...
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Cancer neuroscience of brain metastasis: When in Rome, do as the Romans do
In this comprehensive review, Karreman & Winkler explore how neural influences on the brain’s metastatic process govern brain tropism, colonization, and growth. Conversely, metastatic cancer has disti...
https://www.cell.com/neuron/fulltext/S0896-6273(25)00588-4
5 months ago
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reposted by
Kevin Zhang
AACR Journals
6 months ago
In the United States, cases of early-onset cancer are on the rise. Featured in a recent
#AACRBlog
on early-onset cancer, this Cancer Discovery article explores how changes in risk factor prevalence and/or improvements in detection could affect risk across an age range. Read more:
buff.ly/NLssp4H
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reposted by
Kevin Zhang
Nature
6 months ago
Hidden in the lungs of some breast cancer survivors are tumour cells that can remain dormant for decades — until they one day trigger a relapse
go.nature.com/41iIdJR
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‘Sleeping’ cancer cells in the lungs can be roused by COVID and flu
Inflammation from the respiratory infections seems to be the culprit, study in mice finds.
https://go.nature.com/41iIdJR
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reposted by
Kevin Zhang
Johns Hopkins Department of Biochemistry and Molecular Biology
7 months ago
Congratulations Dr. Alexis Carey! Alexis Carey is in the Cellular & Molecular Medicine program and successfully defended her PhD today. In today's seminar she shared her about work in the Weeraratna Lab on “Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment”
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reposted by
Kevin Zhang
JHU Bloomberg Distinguished Professorships
7 months ago
Listen to BDP
@ashi-w.bsky.social
discuss her work in
#melanoma
research on the Kimmel Cancer Center podcast, Cancer Matters.
hopkinskimmel.libsyn.com/cancer-matte...
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Johns Hopkins Kimmel Cancer Center Podcasts: Cancer Matters with Dr Bill Nelson - Melanoma Research
Dr Bill Nelson talks with Dr Ashani Weeraratna about her work in melanoma research, the progress that has been made in treating patients with melanoma, and the importance of federal research funding i...
https://hopkinskimmel.libsyn.com/cancer-matters-with-dr-bill-nelson-melanoma-research
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reposted by
Kevin Zhang
Richard Sever
8 months ago
"No tumor is an island" and "oncology recapitulates embryology" - a fascinating conversation with the incredible
@ashi-w.bsky.social
at the CSHL symposium on aging. We talk about how cancer rates increase with age, the T(I!)ME, and the role of Wnt signaling
www.youtube.com/watch?v=_Txf...
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Interview with Ashani Weeraratna
YouTube video by CSHL Leading Strand
https://www.youtube.com/watch?v=_Txfiow4iZI
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reposted by
Kevin Zhang
American Association for Cancer Research (AACR)
9 months ago
This year’s 11 NextGen Stars will share their findings on cancer cartography, the dark proteome, cancer-resistant tissues, and more at
#AACR25
. Learn more about their work and its future implications on the
#AACRBlog
:
www.aacr.org/blog/2025/04...
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We explore the utility of an immunohistochemical panel consisting of Sox10, p16, and cyclin D1 in differentiating MAP kinase-activated low-grade gliomas from piloid gliosis.
#neuropath
#pathsky
journals.lww.com/ajsp/fulltex...
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Increased SOX10, p16, and Cyclin D1 Immunoreactivity... : The American Journal of Surgical Pathology
available stains, we hypothesize that a limited panel including SOX10, p16, and cyclin D1 may be useful in differentiating mitogen-activated protein (MAP) kinase-activated low-grade gliomas from piloi...
https://journals.lww.com/ajsp/fulltext/9900/increased_sox10,_p16,_and_cyclin_d1.465.aspx
about 1 year ago
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reposted by
Kevin Zhang
Edna Cukierman - Tumor Microenvironment
about 1 year ago
Congratulations to the new
#AACR
#TME
working group Chair elect!!! The one and only (best friend and colleague)
@ashi-w.bsky.social
www.aacr.org/professional...
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TME Working Group Chair-Elect Election Results
Congratulations to Ashani T. Weeraratna, PhDTME Working Group Chair-elect 2025-2026 Our thanks to Ashani T. Weeraratna, PhD, and Marina Pasca di Magliano, PhD, for standing for election, and to the TM...
https://www.aacr.org/professionals/membership/scientific-working-groups/tumor-microenvironment-working-group/tme-chair-election-results/
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Golden weekend
about 1 year ago
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reposted by
Kevin Zhang
Varun Venkataramani
about 1 year ago
🧵Just in time for : New research from the Venkataramani lab @CellCellPress maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here:
authors.elsevier.com/sd/article/S..
.
@ekinreyhan.bsky.social
@svenjaktetzlaff.bsky.social
1/15
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reposted by
Kevin Zhang
Maria Gubbiotti, MD,PhD
about 1 year ago
Myxopapillary ependymoma grossly has a characteristic sausage-shaped appearance. Commonly found associated with the filum terminale, it has a fibrillary glial appearance in a myxoid background. Though previously categorized as CNS WHO grade 1, it is now considered grade 2
#pathsky
#medsky
#neuropath
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Advances in cancer research in 2024
aacrjournals.org/cancerdiscov...
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Reflections on Advances in Cancer Research in 2024
There have been many impactful advances in basic, translational, and clinical cancer research in 2024. An important mission of Cancer Discovery is to ensure the timely dissemination of innovative ways...
https://aacrjournals.org/cancerdiscovery/article/14/12/2346/750135/Reflections-on-Advances-in-Cancer-Research-in
about 1 year ago
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reposted by
Kevin Zhang
Giorgio Seano
about 1 year ago
Among the Cancer-related Starter Packs currently available, I didn’t find one on Tumor Microenvironment. Here, the list of who I found until now… If you want to be added, please reply below!
go.bsky.app/CtQMJyW
add a skeleton here at some point
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reposted by
Kevin Zhang
Piotr Jung-Sillah
about 1 year ago
go.bsky.app/7xTwrrn
add a skeleton here at some point
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reposted by
Kevin Zhang
Siegenthaler Lab
about 1 year ago
🧠 barriers & neurovasculature starter pack - please reply here if you are not on it yet & would like to be added 😊
go.bsky.app/RB6RXKy
add a skeleton here at some point
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