New Blue Ridge rankings! 📊 Always humbling to see these rankings; much gratitude for the team behind the numbers. 🔗 brimr.org/brimr-rankin... Proud to see Icahn School of Medicine at Mount Sinai rise to #6 nationally in EM NIH funding (from #7). 🚀 @medsky.social @mountsinainyc.bsky.social

The positivity of the novel orphine substance N-propionitrile chlorphine, or "Cychlorphine" in fatal drug overdoses has increased since mid-2025 when the Chinese government placed nitazene analogues under generic control, per CFSRE www.cfsre.org/nps-discover...

Our new paper out in Addiction from the multicenter Fentalog Study examines who is more likely to have xylazine detected in non-fatal opioid overdose presenting to the ED. This is patient-level toxicosurveillance. #Xylazine #medsky onlinelibrary.wiley.com/doi/10.1111/... Thread 1/🧵

The updated CDC Fentalog Study dashboard is a sobering reminder that the opioid supply is no longer just “fentanyl.” Polysubstance exposure is now the rule, not the exception, and surveillance must evolve accordingly. #PublicHealth 🧵 www.cdc.gov/overdose-pre...

1/ 🚨 New TOXIC Fentalog quarterly report on multi-city toxicology testing shows fentanyl & other synthetic drugs dominate suspected overdose cases in US ERs. Findings offer a near real-time look at the street drug market. #medsky #PublicHealth 🧵 www.cfsre.org/nps-discover...

Publication: Black patients less likely than white patients to receive outpatient treatment referrals after #opioid #overdose ED visits, per ToxIC Fentalog study. Findings underscore need to address disparities in post-overdose care. ➡️ bit.ly/4l1hFE2 @jamanetworkopen.com @maninialex.bsky.social

🚨Publication Alert🚨 bit.ly/46U3nl6 #Xylazine found in 1 in 5 nonfatal #opioid #overdoses across 10 U.S. EDs, mostly alongside #fentanyl. Exposure highest in NE vs. rare in the West. Regional trends underscore need for targeted public health responses. #MedToxTuesday @maninialex.bsky.social

🚨Publication Alert🚨These findings focused on the presence of para-fluorofentanyl (PFF) point to important differences in OD response/treatment linked to fentanyl analogs w/ sex-specific effects that merit further investigation. 📖https://bit.ly/3Gv0gp3 @ziadkazzi.bsky.social @maninialex.bsky.social

Among patients with opioid overdose in emergency departments, Black patients received outpatient referrals less frequently than White patients, with rates of 5.7% versus 9.6%. https://ja.ma/44kiKjO

July 1. Day One. - You will feel overwhelmed (That’s normal) - Courage isn't the absence of fear - Ask for help early and often - Nobody expects you to know everything - Efficiency comes with time - Trust the process 💙 Welcome. We’ve got your back. #InternYear #Medsky

🚨HUGE SCIENCE WIN ALERT🚨 NIH Grants to be restored en masse!!! Thank you Judge Young for standing up for science! #StandUpforScience #SummerFightforScience

Tianeptine, or ‘gas station heroin,’ can be addictive and cause serious side effects WASHINGTON (AP) — Health officials want you to think twice before buying one of those brightly colored little bottles often sold at gas stations, convenience stores and smoke shops. Sometimes called “gas station…

1/ Exciting news: Our team has been awarded a NIDA R01 grant to fund "Fentalog II", a continuation of our groundbreaking collaboration to detect novel fentanyl analogue overdoses in EDs across ten major hospitals over five years. #syntheticopioids #Medsky 🧵 www.mountsinai.org/about/newsro...

1/ Our new study in Academic Emergency Medicine analyzed 1,265 ED patients with severe QTc prolongation (≥500 ms) after drug overdose. What predicts dangerous ventricular dysrhythmias in this high-risk group? #cardiotoxins #overdose #Medsky 🧵 pubmed.ncbi.nlm.nih.gov/40492421/

“In an unusual act of public protest, more than 340 scientists and staff at the National Institutes of Health today released a statement charging NIH officials and their superiors with politicizing science.” www.science.org/content/arti... #StandUpForScience #BethesdaDeclaration

Even he agrees with me! #medsky abcnews.go.com/amp/Health/r...

Great primer and review of the landscape on Methadone for EM docs and emergency care providers #opioidcrisis #Medsky www.acepnow.com/article/libe...

1/ Something weird is happening at NIH. For two weeks in a row, the NIH Weekly Guide has listed zero new funding opportunities. That’s not normal. At all. A short thread on why this is a statistical and strategic outlier: #Medsky

The Trump administration continues to interfere with medical research, this time by forbidding NIH scientists from attending conferences - even on their own time and paying their own way. #medsky www.reuters.com/business/hea...

1/ Supervised Consumption Sites (SCSs) work — and Canada has the data to prove it. A recent ecological and spatial analysis shows a striking 67% reduction in overdose mortality within 500m of SCSs. #ACMT2025 #PublicHealth #Medsky

Caught up on #ThePitt. As an ER charge nurse, I know that mass casualty events are a constant, avoidable reality. Hopefully the show illustrates to even one person the physical and emotional damage from gun violence and moves them to vote for a safer reality for all of us. @everytown.bsky.social

The vaccine against Shingles helps protect against dementia, results of a natural experiment, adding to prior evidence "implications are profound" New @nature.com www.nature.com/articles/d41... nature.com/articles/s41...

Collecting my thoughts at the end of one of the worst days of my life... At NIH, > 1300 people were RIFed. These range all across the board from institute directors to low level administrative staff. Communication staff and procurement appear to be hardest hit as anticipated from the HHS plan 1/n

There is no other way to say this: Today is the day the CDC was essentially dissolved. What's left is a husk. People will die as a direct result. www.wired.com/story/cdc-gu...

It’s April 1 and still no news about the noncompetitive renewal of our #NIH #R35 award that should enter year 2 today. It’s Schrödinger’s grant How many others are in the same boat? 🧪

How I will remember April Fools' Day 2025. Reckless. My heart is out for these dedicated folks at NIH, FDA and CDC www.statnews.com/2025/04/01/h...

🧵1/5 New NIH Director Jay Bhattacharya outlines bold new priorities in his welcome message to NIH staff. A physician-economist from Stanford, Bhattacharya signals a shift toward outcomes-driven research and public trust-building. Here’s what’s coming... ⬇️ #MedSky www.nature.com/articles/d41...

🧬 Key scientific leaders are being removed! 🧬 NIH directors—known for their expertise and institutional knowledge—are being ousted Result? ✅Undermines public health ✅Erodes scientific integrity ✅Risks unchecked actions A short 🧵 1/ #NIH #CDC #FDA #AcademicSky #MedSky #Science

This doesn't look good, folks www.nature.com/articles/d41...

In <24 hours, Covid funding is DOGEd across HHS, CDC, NIH as if it and Long Covid didn't exist and there is no worry for future pandemics www.science.org/content/arti... www.nbcnews.com/health/healt... www.science.org/content/arti...

🚨 Big news from #IcahnEM 🚨 The Department of Emergency Medicine at the Icahn School of Medicine at Mount Sinai is now ranked #7 nationally in NIH funding, according to the 2024 @brimr_org report. 🧵 #Medsky brimr.org/brimr-rankin... 1/

This is maliciously stupid legislation that will not help anyone & will divert desperately needed resources into already-bloated law enforcement budgets without saving a single life or helping a single American citizen. It even criminalizes (bans completely) compounds that REVERSE FENTANYL OVERDOSE.

I know a lot of folks are raving about “The Pitt”, which I still need to see. But in 1976, Season 6 of Emergency!, there was a pivotal change in the portrayal of EM that just doesn’t get the recognition it should. The birth of a specialty in the media Ping @ACEPNation

CHECK IT OUT 🔎Fentalog's newest findings show that less than 1% of patients who experienced an opioid-related overdose required delayed intubation, with most cases relating to non-respiratory related conditions. Read more here: doi.org/10.1016/j.an...

🧵1/ Our new study in Annals of Emergency Medicine on opioid OD in the ED: Out of 1,591 cases, delayed intubation (>4h) was rare—only 9 patients (0.6%). What does this mean for emergency medicine? @acmtmedtox.bsky.social #OpioidCrisis #medsky www.annemergmed.com/article/S019...

The ER PA I'm working with doesn't know who Noah Wyle is... #medsky

Vitamin A and cod liver oil won’t cure measles?! Seriously, one child has died—there is no reason for this to be happening. No child should have measles—let alone die of them in 2025. When will they learn?!

From: apnews.com/article/meas...

Do not take medical advice from RFK Jr. He is not a doctor. #notadoctor #medsky

Studies show that funding from the National Institutes of Health (NIH) contributed to 354 of 356 drugs (99.4%) approved by the FDA from 2010 to 2019. Recklessly slashing NIH funding will mean that patients will be waiting much longer for life-saving treatments.

NEW: Pregnancy became far more dangerous in Texas after the state banned abortion, according to ProPublica’s first-of-its-kind analysis, which found the sepsis rate for women hospitalized as they miscarried in the 2nd trimester shot up by more than 50%. https://propub.li/43487Tj

BREAKING: New memo reveals NIH is issuing new and continuing grants with “the previously approved negotiated indirect cost rates” and not the 15% indirect cost cap the Trump administration was seeking to impose. #Resistance #medsky popular.info/p/breaking-n...

🚨 NIH Indirect Cost Cuts: A Thread 🚨 1/ Late on a Friday, NIH dropped a bombshell—effective next week, ALL NIH grants will have a flat 15% indirect cost cap. No negotiation. No exceptions. 📉💰 grants.nih.gov/grants/guide... #ResearchFunding #SciencePolicy #medsky

🧵 1/ Our new review paper on #nitazene overdoses: Ultra-potent synthetic opioids bind to the mu-opioid receptor at up to 1.4x the strength of fentanyl. The opioid crisis is evolving, and our response needs to keep up #opioidcrisis #medsky 10.1007/s13181-025-01059-8 pubmed.ncbi.nlm.nih.gov/39904921/

The people who are trying to set rules for career scientists couldn’t even pass introductory biology or chemistry

1/ 🚨 Our new study: Patients presenting to US emergency departments (EDs) with opioid overdoses have an HIV prevalence 9x higher than the general population. The opioid crisis and HIV epidemic are colliding in ways we can’t ignore. #OpioidCrisis #HIVResearch #medsky 🧵 doi.org/10.1016/j.dr...

#PainResearch #MedSky #PedSky #addictionsci #neuroskyence 🛟 Godspeed !! FDA approves first new type of pain medication in 25 years www.cnn.com/2025/01/30/h...

1/ 🚨 Our new article in Substance Use & Misuse explores suicidal intent in patients with nonfatal opioid overdoses. Key finding? 6.4% of cases showed intent tied to prescription opioids, not illicit ones. #OpioidCrisis #PublicHealth #medsky 🧵 doi.org/10.1080/1082...

Trump has basically paused the work on the NIH for the time being. This is unprecedented and terrifying. The NIH drives the world’s health research and any pause delays cures. #MedSky www.science.org/content/arti...

ScienceInsider has confirmed h/t @merz.bsky.social. NIH has frozen study sections through at least Feb. 1 www.science.org/content/arti...