Loving my state rn. California’s $23 Billion Plan to Restore Federal Cuts to Scientific Research www.nytimes.com/2025/09/13/u...

AI methods are great tools for advancing drug safety surveillance. We show that LLMs can accurately identify and extract essential concepts from messy product drug labels. Just published in _Drug Safety_! Great work led by @undinagislad! link.springer.com/article/10.1...

We used AI to audit 21,000+ RCTs. The result? -- only 15% of trials fully comply with CONSORT guidelines. Transparency in clinical trials has a long way to go. Amazing work by Apoorva in my group! jamanetwork.com/journals/jam...

The top three science funders are the US, China, and Japan. The three fund more science than every other country, combined. In 2024, the US funded more scientific research than China and Japan, combined. The US also funds more science than every other country except for Japan and China, combined.

The 2025 volume of the Annual Review of Biomedical Data Science is now online. Take a look at the most read article from this new volume, "Spatial Transcriptomics Brings New Challenges and Opportunities for Trajectory Inference" arevie.ws/45D2NWD @marylynritchie.bsky.social @tatonetti.bsky.social

This creates a fun game that rewards superfluous, outlandish (dare I say outre?) verbiage.

With the correct rhetorical device you can make complete jibberish sound like poetry. Just ask Shakespeare (or better read Forsyth's The Elements of Eloquence)

Just came across this fail. Literally everything that's wrong with AI/tech in healthcare. Not only is the patient and doctor buried in their devices, but they're facing AWAY from each other 🤦‍♂️!! Technology should facilitate and center the humanity of healthcare. Not do whatever this is.

I’m petrified about today’s science news. Genetically modifying crabs to have cheetah genes? This could go sideways fast.

What is Vibe Coding and how can it be used to advance biomedical research? @tatonetti.bsky.social & I explain in this editorial biodatamining.biomedcentral.com/articles/10.... #bioinformatics #datascience #coding #vibecoding

Vibe coding is coming for biomedical software development, my first editorial as Co-Editor-in-Chief of @BioDataMining with @moorejh.bsky.social biodatamining.biomedcentral.com/articles/10....

If anyone is wondering, yes we will be monitoring the safety and side effects of drugs from the moment they hit the market

So the market for our drug safety monitoring algorithms just opened up 👀

Excited that our paper on GenAI-based text normalization is out at Journal of Biomedical Informatics! If you ever had a bunch of messy text and need to map it to a controlled terminology, then this is the method for you. www.sciencedirect.com/science/arti... Special 👏 to Jacob Berkowitz!!

Learn observational data from the best. @ColumbiaDBMI and @OHDSI are offering summer school to learn all the real-world-data analysis tips and tricks. columbiauniversity1.regfox.com/ohdsi-summer...

✅ PASSED SENATE TRANSPORTATION COMMITTEE: SB 445 by @scottwiener.bsky.social that streamlines permit approval process for transit projects to tackle cities that cause costly delay against transit.

What a fabulous discussion and meeting! Off to a fun start.

Looking forward to starting the Nexus Informatics conference tomorrow morning. First up - @tatonetti.bsky.social Nicholas Tatonetti delivering our opening keynote! Can't wait! I will be giving the Friday morning keynote, "Welcome to the Jungle – Real World Data Surrounded by Data Gardens" !

Our OnSIDES db -- the worlds most up-to-date resource of drug side effects is published at @MedCellPress For all your drug safety analysis and prediction needs. OnSIDES is the first resource to combine US, UK, EU, and Japanese data all in one place. www.cell.com/med/abstract...

In 2018 I wrote about how medical science could benefit from how humans approach cooking -- all of us continuously testing and experimenting new ideas constantly. Feels even more true in 2025. www.annualreviews.org/content/jour...

We just opened a new collection at BioData Mining for submissions! Our ability to collect data has outpaced our ability to make sense of it. In this collection we want to see papers that are addressing this growing gap. www.biomedcentral.com/collections/...

Thank you @amiainformatics.bsky.social for an having me for another fun Translational Bioinformatics Year in Review! #YIR25 #IS25 Here are the slides of the top papers of the year: tatonettilab-resources.s3.amazonaws.com/TBI-Year-in-...

Putting the final touches on tomorrow's Translational Bioinformatics Year-in-Review *Playlist* @AMIAinformatics #IS25 #YIR25 open.spotify.com/playlist/5YE...

reviewing papers for my annual Translational Bioinformatics Year-in-Review at the AMIA 2025 Summits in Pittsburgh and came across this gem -- needless to say I feel attacked.

If you're in the US, considering Europe for your PhD, and you identify as a minority, I will chat with you and review any application documents you need 🧪

Just received notice that our grant was terminated. 5R24AG066599-03 TheRiseRegistry.org

A Primer on Indirect Cost Rates

1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...

Saw this great suggestion from @roxanadaneshjou.bsky.social, so I’ll go. NIH funded helped my lab discovery that using ceftriaxone (generic antibiotic) and lansoprazole (Prevacid) together will cause dangerous arrhythmias.

Huge drug effects news!! Major breakthrough in figuring out what in grapefruit interferes with drug metabolism. Can’t wait to dive into the solution to this decades long mystery. 🤓 www.nytimes.com/2025/01/10/s... via @NYTimes

Branding large language models as artificial intelligence primes customers to believe they have capabilities they lack cacm.acm.org/opinion/arti... #artificialintelligence #llms

"We estimate that the sources of drinking water for up to 23 million Americans could be contaminated above regulatory thresholds by wastewater-derived PFAS [forever chemicals] alone." @pnas.org www.pnas.org/doi/10.1073/...

Chaz Dean is the Dr Zizmor of LA. #iykyk

Whoa! In @NEJM_AI: A Multimodal Biomedical Foundation Model Trained from 15 Million Image–Text Pairs… fully open-access foundation model! ai.nejm.org/doi/full/10....

Women leave academia at higher rates than men at every career stage, and attrition is especially high among three groups: tenured faculty, women in non-STEM fields, and women employed at less prestigious institutions, a #ScienceAdvances analysis finds.

Trustworthy implementation of #AI in #cardiology: a roadmap from the European Society of Cardiology and its Digital Cardiology and #ArtificialIntelligence Committee bit.ly/4iNOxAg

TLab @ Cedars-Sinai is looking for summer interns in data science, drug safety science, and health AI! 🔬 Research drug safety, cancer care & more 📍 LA-based (Pacific Design Center) 🗓 Apply by Jan 27! 👉 Learn & grow with us! More info here: docs.google.com/document/d/1... #HealthAI #Internship

Today's @washingtonpost.com editorial washingtonpost.com/opinions/202... Happy Thanksgiving!

The metaverse remains a work in progress, but improvements in how it handles ethical concerns and addresses cultural issues could push it further along the path to mass adoption cacm.acm.org/research/eth... #metaverse #ethics

Very interesting work by Tade Souaiaia et al on the non-polygenic architecture of the extremes of complex traits. For many traits, polygenic scores show "regression to the mean" around the tails, as extreme traits are mostly due to rare alleles. www.biorxiv.org/content/10.1...

The human proteomic revolution proceeds with high-throughput assessment, AI analytics, correlation with health and disease, drug interactions, biomarkers www.cell.com/cell/fulltex...

Gorgeous whole-brain RNA staining method from Per Uhlén’s group, Shigeaki et al. www.science.org/doi/10.1126/...

Meet BB-TEN, an AI model that stages cancer from pathology reports in record time. Our team, led by Jenna Kefeli, shows how this advance can accelerates clinical trials & expands access to cutting-edge treatments. www.cedars-sinai.org/newsroom/new... #CancerInnovation #AIResearch #CedarsSinai

Nice work from @tatonetti.bsky.social & team! www.cedars-sinai.org/newsroom/new... #artificialintelligence #bioinformatics

NASA’s new rendering of the Christmas Tree Nebula

Investing in the NIH yields massive returns. $2 for every $1 spent. t.co/HCTcx2RWZQ

Announcing the re-release of our online interface to the OnSIDES database at onsidesdb.org! You can search all the side effects we parsed from the structured product labels.

Cancer staging is essential to research and care, but largely remains locked in unstructured pathologists notes. Today, we published BB-TEN in @NatureComms an automatic model for extracting TNM stage from path notes and show it works OOTB on out-of-sample data! www.nature.com/articles/s41...

New paper out! 📝 Using EHR data from two major health systems, we found that heparin therapy is linked to a delayed Alzheimer’s diagnosis (+1 year). Exciting potential for understanding AD protection and prevention. 🧠💡 #Alzheimers #AI #EHR www.nature.com/articles/s41...

EHRs are a boon for biomedical research! But, as we find in our latest pre-print, even well-intentioned data quality filters lead to datasets biased against minoritized populations. www.medrxiv.org/content/10.1...