SOURJYA MAL
@sourjyamal.bsky.social
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📥 226
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Doctoral student @vangemmerenlab Catalysis | Glycochemistry | C–H Activation
reposted by
SOURJYA MAL
van Gemmeren Lab
3 months ago
Check out this excellent review by
@sourjyamal.bsky.social
on carboxylic acid directed C(sp³)–H functionalization, covering distinct mechanistic strategies (C–H activation, HAT, etc), catalyst design principles, and their applications in building complex molecules.
doi.org/10.1021/acs....
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reposted by
SOURJYA MAL
van Gemmeren Lab
3 months ago
Another major milestone has been achieved! Sourjya Mal presented an outstanding defense and has now well-deservedly earned the title of Dr. Mal!!!🎓 Congratulations from the van Gemmeren group, and all the best for your future journey!
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reposted by
SOURJYA MAL
van Gemmeren Lab
5 months ago
Just one ''click'' away! Dive into our newest publication showcasing non-directed C-H olefination as a powerful tool to access versatile linchpins for bioconjugation and/or ABPP studies!
doi.org/10.1002/chem.202600018
Congratulations to Tommaso Braga and
@mariahergert.bsky.social
!
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reposted by
SOURJYA MAL
van Gemmeren Lab
7 months ago
A direct synthesis of versatile active esters! Massive congratulations to Simon Kaltenberger, Joshua Meinshausen,
@jyotirmoydey.bsky.social
and Celia Sanchez-Gonzalez on the development of a widely applicable sterically controlled alkoxycarbonylation of arenes now in JACS Au
doi.org/10.1021/jacs...
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reposted by
SOURJYA MAL
van Gemmeren Lab
9 months ago
Exttemely proud of this computational and experimental mechanistic work headed by
@chimicafritz.bsky.social
and supported by
@monikaravi.bsky.social
just out in
@angewandtechemie.bsky.social
doi.org/10.1002/anie...
#chemsky
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reposted by
SOURJYA MAL
van Gemmeren Lab
10 months ago
Access SEAr-type products in typically disfavored positions! Contratulatons to Rita,
@jyotirmoydey.bsky.social
and Elisa showin in Org. Lett. how nondirected C-H activation and oxidative cleavage can be used to obtain challenging regioisomers in formylation and carboxylation
doi.org/10.1021/acs....
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reposted by
SOURJYA MAL
Synlett Journal
11 months ago
A simple, scalable method by Jurk & van Gemmeren
@vangemmerenlab.bsky.social
to convert secondary sulfonamides into sulfonyl fluorides using affordable
#DAST
⚗️, yielding excellent results! These sulfonyl fluorides readily couple with amines to create diverse libraries.
#SuFEx
👉
buff.ly/hjkyEap
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The final version of our
@vangemmerenlab.bsky.social
'Molecular Stitching' approach, enabling one-step access to a diverse library of γ-alkylidene lactones, is now out in
@chemicalscience.rsc.org
#MyFirstChemSci
Link to the full article:
doi.org/10.1039/D5SC...
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Synthesis of γ-alkylidene lactones via molecular stitching of carboxylic acids and olefins
In this study, we describe a direct palladium-catalyzed tandem β-C(sp3)–H olefination/lactonization strategy for the one-step synthesis of γ-alkylidene lactones. The reaction is enabled by an N-acyl s...
https://doi.org/10.1039/D5SC03349G
12 months ago
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reposted by
SOURJYA MAL
van Gemmeren Lab
12 months ago
Congratulations to aol three
@uni-kiel.de
candidates who were selected to participate in the Lindau Nobel Laureate meeting. In particular of course our very own
@sourjyamal.bsky.social
. A well deserved recognition of his excellent doctoral studies.
#proudPI
#chemsky
www.uni-kiel.de/de/detailans...
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Drei Nachwuchsforschende der Uni Kiel bei Nobelpreisträger-Tagungen
Die Einladungen sind auch eine Auszeichnung für die Chemie und die Wirtschaftswissenschaften an der CAU.
https://www.uni-kiel.de/de/detailansicht/news/116-nobelpreistagung
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reposted by
SOURJYA MAL
van Gemmeren Lab
about 1 year ago
Great job Edis and
@sourjyamal.bsky.social
! Their work on the synthesis of γ-Alkylidene Lactones has just been accepted for publication in the
@rsc.org
journal
@chemicalscience.rsc.org
doi.org/10.1039/D5SC...
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reposted by
SOURJYA MAL
van Gemmeren Lab
about 1 year ago
Just saw on the OL homepage that the article currently leads the journals most read list, thanks for all the interest in our work!
pubs.acs.org/action/showM...
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Organic Letters :
https://pubs.acs.org/action/showMostReadArticles?journalCode=orlef7
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Check out our newest C(sp³)–O bond formation strategy:
doi.org/10.1021/acs....
add a skeleton here at some point
about 1 year ago
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reposted by
SOURJYA MAL
van Gemmeren Lab
about 1 year ago
Congratulations to Edis and
@sourjyamal.bsky.social
, who have completed their studies on a new and efficient approach towards gamma-alkylidene lactones directly from carboxylic acids and lactones now posted on
@chemrxiv.bsky.social
chemrxiv.org/engage/chemr...
#chemsky
#chemistry
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Check out my latest preprint from
@vangemmerenlab.bsky.social
, where we disclosed a one-step approach to access γ-alkylidene lactones by stitching together aliphatic acids and styrenes, enabled by N-Acyl Sulfonamide ligand.
doi.org/10.26434/che...
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Synthesis of γ-Alkylidene Lactones via Molecular Stitching of Carboxylic Acids and Olefins
In this study, we describe a direct palladium-catalyzed tandem β-C(sp3)–H olefination/lactonization strategy for the one-step synthesis of γ-alkylidene lactones. The reaction is enabled by an N-acyl s...
https://doi.org/10.26434/chemrxiv-2025-sjd1z
about 1 year ago
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reposted by
SOURJYA MAL
van Gemmeren Lab
over 1 year ago
Thanks for all the interest in the study. It is now amongst the currently most read in ACS Catalysis
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Smashing distal C–H bonds of the unprecedented β-non-quaternary acids has been a formidable task over the years; several years of our involvement in 'Ligand Design' finally broke the deadlock! Thanks to
@vangemmerenlab.bsky.social
for guiding us to achieve this feat !
add a skeleton here at some point
over 1 year ago
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reposted by
SOURJYA MAL
van Gemmeren Lab
almost 2 years ago
We have developed a direct gamma-lactonization of carboxylic acids. The scope includes beta-non-quaternary subatrates that were until now out of reach for carboxylic acid gamma-C-H activation. Congratulations to Tianxiao and Sourjya. Have a look at the study now posted on ChemRXiv
t.co/Wu0XtwsEQR
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reposted by
SOURJYA MAL
van Gemmeren Lab
about 2 years ago
Our work on the direct fluorination of carboxylic acids has just appeared in @NatureSynthesis! (
www.nature.com/articles/s44...
). This terrific study bySourjya Mal, Friedrich Jurk, and Kerstin Hiesinger is highlighted in a press release by our University:
www.uni-kiel.de/en/details/n...
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Pd-catalysed direct β-C(sp3)–H fluorination of aliphatic carboxylic acids - Nature Synthesis
C–F bond formation using transition-metal catalysis is a challenge owing to the high energy barrier associated with reductive elimination. Now the direct β-C(sp3)–H fluorination of aliphatic carboxyli...
https://www.nature.com/articles/s44160-024-00578-6
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