A.Bosson
@astroantho.bsky.social
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Astrocyte nerd CRCHUM - Montreal Murphy-Royal lab
https://www.murphyroyallab.org/
pinned post!
A touch of blue velvet LUT with this
#FluorescenceFriday
GCaMP8 astrocytic activities at the 2p
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about 1 year ago
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Astrocytic opposition for this
#FluorescenceFriday
, Cytoskeleton vs. Cytoplasm. ⚪️GFAP 🟠eGFP 🔵DAPI Imaging credit: undergrad Camila Cabarcas
4 days ago
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reposted by
A.Bosson
Ciarán Murphy-Royal
6 days ago
Couldn't wait for Friday to share this really incredible image from superstar undergraduate student Camila Cabarcas, iInvestigating astrocyte morphology Fingers crossed for Camila as she's at U Cincinnati this week to interview for grad school!
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reposted by
A.Bosson
Ciarán Murphy-Royal
about 1 month ago
Delighted to share our first preprint of the year! A project that we're all really proud of in the lab led by
@ossamaghenissa.bsky.social
with
@mathiasgua.bsky.social
in which we set out to test the role of basolateral amygdala astrocytes in anxiety behaviour.
www.biorxiv.org/content/10.6...
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Astrocytic Encoding of Threat in the Basolateral Amygdala
The basolateral amygdala (BLA) has long been implicated in threat detection and the generation of anxiety states. While previous experiments have demonstrated the important role of BLA principal neuro...
https://www.biorxiv.org/content/10.64898/2026.01.07.697973v1
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Went fishing for this
#FluorescenceFriday
(GCaMP6s zebrafish larvae)
2 months ago
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The views we are lucky to witness from the
@crchum.bsky.social
3 months ago
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A.Bosson
Jun Nagai
4 months ago
Just out in Nature! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory
nature.com/articles/s41...
. New astrocyte tools are openly available at Addgene:
addgene.org/Jun_Nagai/
. 1/8
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reposted by
A.Bosson
Ciarán Murphy-Royal
5 months ago
L’impact du stress sur le cerveau dépendrait du sexe
www.lapresse.ca/actualites/s...
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Étude réalisée à Montréal | L’impact du stress sur le cerveau dépendrait du sexe
Le cerveau des mâles et des femelles ne réagit pas de la même manière au stress, démontrent pour la première fois des travaux réalisés à Montréal.
https://www.lapresse.ca/actualites/sciences/2025-09-05/etude-realisee-a-montreal/l-impact-du-stress-sur-le-cerveau-dependrait-du-sexe.php
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reposted by
A.Bosson
Masha Prager-Khoutorsky
6 months ago
Thrilled to share our new study showing microglia prune astrocyte processes in adult brain, to regulate synaptic transmission, hypothalamic neuron activity, and salt-induced hypertension in🐀. Huge team effort - congratulations to all🥂🍾🎉
add a skeleton here at some point
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Go Lewis 👏👏👏
add a skeleton here at some point
7 months ago
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A.Bosson
Science News
9 months ago
Sleep loss is a metabolic disorder "This review describes how sleep deprivation increases resting energy expenditure, leading to the development of a negative energy balance in highly active cells like neurons."
www.science.org/doi/10.1126/...
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Sleep loss is a metabolic disorder
Sleep deprivation shifts metabolic resources and deprioritizes processes that support cognition.
https://www.science.org/doi/10.1126/scisignal.adp9358
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Happy to see that the 2nd part (2018 to 2021) of my postdoc work is now out as a preprint.
add a skeleton here at some point
9 months ago
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reposted by
A.Bosson
CANGlia
9 months ago
@lewisholt.bsky.social
sharing some cool data about astrocytes driving stress-induced behaviour!
#astroglia
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reposted by
A.Bosson
Ciarán Murphy-Royal
11 months ago
Very happy to share several common protocols used in our lab for the second edition of the book "Astrocytes: Methods and Protocols"
@lewisholt.bsky.social
@astroantho.bsky.social
Thanks
@dibenedetto-lab.bsky.social
for being a very patient editor!
link.springer.com/book/10.1007...
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Astrocytes
This book gathers methods essential for investigating the multifaceted roles of astrocytes in both physiology and pathological conditions.
https://link.springer.com/book/10.1007/978-1-0716-4366-2
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reposted by
A.Bosson
Ciarán Murphy-Royal
11 months ago
Montréal glia people / neuroscience community - I'm hosting Jun Nagai (RIKEN) on April 2nd at the
@crchum.bsky.social
If you're interested see details below, or reach out to me! Open to all.
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reposted by
A.Bosson
Ciarán Murphy-Royal
about 1 year ago
Not sure if our 'striking image' we submitted will get used but here it is. Super striking, if you ask me! Credit -
@mathiasgua.bsky.social
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reposted by
A.Bosson
Ciarán Murphy-Royal
about 1 year ago
Very honoured to be named the researcher of the month by SENSUM - the mental health and neuroscience strategy at
@umontreal.ca
www.sensum.umontreal.ca/en/2025/01/3...
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🎉 Félicitations à notre chercheur du mois de février – Dr Ciaran Murphy-Royal ! 🎉
Dr. Ciaran Murphy-Royal is an assistant professor in the Department of Neurosciences at the Université de Montréal and a principal investigator at the Centre de Recherche du Centre Hospitalier de l’Un...
https://www.sensum.umontreal.ca/en/2025/01/31/🎉-felicitations-a-notre-chercheur-du-mois-de-fevrier-dr-ciaran-murphy-royal-🎉/
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reposted by
A.Bosson
Justin Lines
about 1 year ago
Astrocyte physiologists and computationalists! Imaging astrocyte structure and function, we discovered and quantified a spatial threshold to astrocyte calcium surge ⭐
doi.org/10.7554/eLif...
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A spatial threshold for astrocyte calcium surge
In astrocytes, there exists an intrinsic spatial threshold of subcellular calcium levels that triggers an astrocyte calcium surge throughout the cell, demonstrating cellular astrocyte calcium integrat...
https://doi.org/10.7554/eLife.90046.3
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A touch of blue velvet LUT with this
#FluorescenceFriday
GCaMP8 astrocytic activities at the 2p
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about 1 year ago
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reposted by
A.Bosson
Allen Institute
about 1 year ago
How convenient - this tree already comes with ornaments! 🎄🧪 Get into the holiday spirit with this beautiful cell tree by
@oozguc.bsky.social
from
@ibecbarcelona.eu
. This beautiful fusion of science and art was made using our Lamin B1 stem cell line! What would you want to see under your cell tree?
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2 eGFP
#astrocytes
contacting a blood vessel with their arborization almost looking like a christmas tree for this
#fluorescencefriday
#astrocyte
about 1 year ago
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reposted by
A.Bosson
Ciarán Murphy-Royal
about 1 year ago
Delighted to share an update to our preprint, reviewed at
@elife.bsky.social
, and now sent back for re-review. Colossal work by the team and driven home by
@mathiasgua.bsky.social
Quick 🧵 of what's new -
www.biorxiv.org/content/10.1...
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Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation
Early-life stress can have lifelong consequences, enhancing stress susceptibility and resulting in behavioural and cognitive deficits. While the effects of early-life stress on neuronal function have ...
https://www.biorxiv.org/content/10.1101/2022.12.11.519598v4
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reposted by
A.Bosson
Shane Liddelow
about 1 year ago
we haven't talked about this in the SKY> exciting preprint from Kevin Guttenplan in Marc Freeman's lab at
@volluminstitute.bsky.social
Adrenergic signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity
www.biorxiv.org/content/10.1...
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reposted by
A.Bosson
eLife
about 1 year ago
10/ Why should you bring
#preprints
into your journal club? Here’s what
#ECRs
stand to gain by looking beyond published papers.
https://buff.ly/3VbvNjT
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Point of View: Journal clubs in the time of preprints
Early-career researchers can learn about peer review by discussing preprints at journal clubs and sending feedback to the authors.
https://buff.ly/3VbvNjT
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reposted by
A.Bosson
Ciarán Murphy-Royal
about 1 year ago
New paper from our neighbours Stephanie Fulton’s lab investigating microglia, inflammation and synaptic transmission in the NAc.
www.biorxiv.org/content/10.1...
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Microglial engulfing of glutamatergic inputs and diminished excitability of D1 medium spiny neurons of the nucleus accumbens by peripheral inflammatory insult
Neuroimmune responses to systemic inflammation can generate anxiodepressive behaviors and psychomotor slowing. The nucleus accumbens (NAc) is a neural hub encoding mood and motivation that contributes...
https://www.biorxiv.org/content/10.1101/2024.12.02.625901v1
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reposted by
A.Bosson
Monica Carson
about 1 year ago
some great starter packs for the
#glia
,
#astrocyte
,
#oligodendrocyte
,
#microglia
,
#neuro
researcher: gliasky, astrocytesky, microglia But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
add a skeleton here at some point
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reposted by
A.Bosson
Lewis Holt
about 1 year ago
Not sure I have any good pictures in the back pocket to beat the calcium imaging from
@mathiasgua.bsky.social
Instead for my first post on Bluesky I want to share the CANglia webinar: trainee series!
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A.Bosson
The Transmitter
about 1 year ago
Still thinking about which neuroscience conferences to attend next year? Explore our events page, featuring a curated list of top neuroscience meetings with topic-based filters. Plus, check out upcoming webinars compiled by
@worldwideneuro.bsky.social
.
thetransmitter.org/events
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reposted by
A.Bosson
Ciarán Murphy-Royal
about 1 year ago
Interesting to see how this is all shaping up! I’m still really proud that the first data paper from my lab went into eLife with the new model, which I think is a great system. (We’ll be updating the manuscript based on these reviews in the very near future)
add a skeleton here at some point
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