Danfeng Cai (@danfengcai.bsky.social)

So happy our paper on TFE3 fusion oncoprotein condensates in translocation RCC is online at Cell Reports! Great collaboration from Eneda Toska, Vito Rebecca, Marston Linehan and Hongkai Ji labs. Proud of the work of trainees Choon Leng So, Jane Lee, Bujamin Vokshi et al www.cell.com/cell-reports...

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TFE3 fusion oncoprotein condensates drive transcriptional reprogramming and cancer progression in translocation renal cell carcinoma So et al. investigate TFE3 fusion oncoproteins (FOs) in translocation renal cell carcinoma (tRCC) and find that TFE3 FOs form transcriptional condensates and drive tRCC progression. The structured coi... https://www.cell.com/cell-reports/fulltext/S2211-1247%2825%2900310-9