Nonmuscle myosin II regulates presynaptic actin and neuronal mechanobiology in Drosophila url: rupress.org/jcb/article-...

With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency | Science | AAAS www.science.org/content/arti...

A massive thank you to the EMBO team for allowing us to publish this story and making the cover. Fat-tagging (myristoylation) at the synapse is critical for synaptic plasticity:) Congrats to all involved n the @meunierlab.bsky.social

5 years in the making! Myristoylation is necessary for LTP and memory acquisition. Great PhD work from Ben Matthews: The EMBO Journal www.embopress.org/doi/full/10....

It looks like Musk will be trying to use x for training his AI. You might remove stuff from there…

Excited for our latest work! We developed nanobinders for the luminal domain of Synaptotagmin 1 (calcium sensor for synaptic vesicles). Thanks among others to @verstrekenlab.bsky.social @opazo.bsky.social @meunierlab.bsky.social @volkerhaucke-lab.bsky.social www.biorxiv.org/content/10.1...

Great to host Laurent Groc and KB Sibarita at Qbi. A single-molecule festival

Today's lectures were given by @meunierlab.bsky.social and Victor Anggono on probing synaptic with super resolution microscopy, and the molecular structure of learning and memory. In the afternoon the students will have a go at super resolution, and TIRF microscopy.

Much needed holidays in Tuscany. Long haul back to Brisbane starts tomorrow 😳

Beautiful Normandie! Thanks to Maité Montero for her kind invitation to visit her lab in Rouen!

On the road again… where am I?

🚨 We're hiring! 🚨 Brandeis University is seeking a tenure-track Assistant Professor in Bioengineering, with a focus on synthetic biology or biomolecular engineering. Please DM me with any questions! academicjobsonline.org/ajo/jobs/28825 (1/2)

So true…

Nice start of the weekend🤩

The sky is the limit again! www.science.org/content/arti...

Beautiful! You should ask @robparton.bsky.social

I am a neuroscientist trying very hard to understand how the chaos in our cells makes sense.

@fredsteyn.bsky.social I am your first follower😊

Very cool

Still amazed by the effect of hericene A on neurite outgrowth in vitro, on BDNF and pTrkB levels in vivo and enhanced cognition in two independent memory paradigms. There is something there! Check this out onlinelibrary.wiley.com/doi/full/10.... #neuron, #microscopy, #axon, #neurotrophins

LRP4 controls SO MUCH more! And it all seems to do so from the PRESYNAPSE (answering that HUGE open question). LRP4 controls synapse growth, cytoskeletal organization, postsynaptic protein recruitment, AND maturation. Multiple processes for the price of one cell surface protein!

Synaptic vesicle exocytosis

Spoiler: syntaxin1 generates nanoscluater on the plasma membrane of PC12 cells in space and time (vertical): see the Matrix-like example of spatiotemporal nanoclustering of syntaxin1. A new full suite of analyses coming out soon...