Vindigni Lab
@vindignilab.bsky.social
📤 373
📥 201
📝 10
Washington University in St. Louis
https://vindignilab.wustl.edu/
Congratulations
@seppai99.bsky.social
for defending her thesis last week!!! Such an honor having her in the lab and excited about the next steps in her career!!!
about 1 month ago
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Vindigni Lab
Stand Up for Science!
3 months ago
The proposed budget slashes NIH by ~40%, devastating medical research, clinical trials, treatment breakthroughs—life-saving work. Thousands of lives at risk for tax cuts for the rich? NO THANKS. Tell your senators to oppose the cuts HERE:
zurl.co/qiKdX
zurl.co/RCR0y
#CutsCostLives
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Will the Senate Save NIH?
Rescuing biomedical research is every bit as important as saving Medicaid.
https://zurl.co/RCR0y
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Vindigni Lab
AyalaLab
3 months ago
Call your legislators to stop slashing the budget of federal funded research in the “Big Beautiful Bill”. Find numbers
@5calls.org
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Vindigni Lab
Congratulations Isabelle for winning the Future of Science Fund at the Keystone!! We are very honored to have such a fantastic student in the lab!!!
5 months ago
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Vindigni Lab
Keystone Symposia
5 months ago
Wrapping up an insightful conference on DNA Replication Gaps, Cancer, and Disease! 🎉 Congrats to our Future of Science Fund winners, Larissa Milano and
@seppai99.bsky.social
! Your achievements inspire us. 🌟
#KSDNARep25
@cantorlab.bsky.social
@albertociccia.bsky.social
@labvincenzo.bsky.social
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Vindigni Lab
Alberto Ciccia
5 months ago
Happy to share our DNA Repair special issue on the replication stress response curated with
@vindignilab.bsky.social
.
www.sciencedirect.com/special-issu...
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DNA Repair | The replication stress response: mechanisms and functions | ScienceDirect.com by ElsevierScienceDirect
High-fidelity DNA replication is constantly challenged by a diverse range of obstacles, including endogenous lesions and secondary structures in the DNA template, tightly bound protein-DNA complexes, ...
https://www.sciencedirect.com/special-issue/10QKT5PDX6K
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Vindigni Lab
Petr Cejka
6 months ago
An interesting collaboration with the
@vindignilab.bsky.social
on the mechanism of resection at gaps. Spoiler alert: the MRE11 complex acts very differently at gaps vs. at DNA breaks
genesdev.cshlp.org/content/earl...
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Check out our new paper led by
@seppai99.bsky.social
from the Vindigni Lab in collaboration with
@cejkalab.bsky.social
delving into the role of nucleases resecting ssDNA gaps generated by PARPi. You can read more here:
genesdev.cshlp.org/content/earl...
6 months ago
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Vindigni Lab
Lopes_Lab
6 months ago
Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30’), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!👇
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Vindigni Lab
AyalaLab
7 months ago
www.washingtonpost.com/science/2025...
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Scientists warn of long-term damage as Trump’s orders slow research
By blocking announcements in the Federal Register, the administration is keeping experts from meeting to evaluate funding proposals.
https://www.washingtonpost.com/science/2025/02/22/trump-research-nih-federal-register/
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Vindigni Lab
Prasad Jallepalli, MD, PhD
7 months ago
this is breaking through keep up the full court press * patients harmed right now * hurts our economy right now * destroys our STEM infrastructure * gift to global competitors and adversaries * dirty tricks by bureaucrats who failed HS chemistry twice
add a skeleton here at some point
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Vindigni Lab
Prasad Jallepalli, MD, PhD
7 months ago
a great way of framing the issue — the bureaucrats are scheming to wreck science they can’t criticize or understand👇🏽 “This really feels like an evil way of using bureaucracy against the process of science, to the contrary of what they say they are doing — streamlining bureaucracy,” Cooper said.
add a skeleton here at some point
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Vindigni Lab
Keith Bellizzi, PhD, MPH
7 months ago
Federal Register Blackout Blocks NIH Funding
www.medpagetoday.com/special-repo...
The White House found a loophole around the judge’s orders to lift the freeze that will cripple research and scientific discovery for years.
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Federal Register Blackout Blocks NIH Funding
New strategy is like pouring 'cement in the pipes of the federal funding infrastructure'
https://www.medpagetoday.com/special-reports/exclusives/114284
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Vindigni Lab
Jeremy Berg
7 months ago
Very important to get this word out!
add a skeleton here at some point
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Vindigni Lab
Jeffrey Dean
7 months ago
Trump Cuts Target Next Generation of Scientists and Public Health Leaders
www.nytimes.com/2025/02/18/u...
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Trump Cuts Target Next Generation of Scientists and Public Health Leaders
A core group of so-called disease detectives, who track outbreaks, was apparently spared. But other young researchers are out of jobs.
https://www.nytimes.com/2025/02/18/us/politics/fda-cdc-health-department-trump.html?smid=nytcore-android-share
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Vindigni Lab
AyalaLab
8 months ago
www.washingtonpost.com/science/2025...
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Trump’s NIH challenges the model that underlies U.S. scientific dominance
The 80-year-old partnership between the federal government and research institutions has made the U.S. the leader in scientific innovation. But now a proposed funding cut threatens the arrangement.
https://www.washingtonpost.com/science/2025/02/11/trump-nih-research-cuts-funding/
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Vindigni Lab
Nicolas Robine
8 months ago
Petition to Reverse the NIH Indirect Cost Cap. Sign and Circulate. Mobilize. Organize.
chng.it/LS57Nk7r6k
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This campaign needs you now
Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)
https://chng.it/LS57Nk7r6k
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Vindigni Lab
Sumedha Agashe
8 months ago
Check out our (
@vindignilab.bsky.social
) Spotlight article highlighting
@durocher1.bsky.social
group's discovery of synthetic lethal SMARCAL1-FANCM interaction, revealing a novel genetic buffering mechanism for genome stability at simple repeat regions during replication
www.cell.com/trends/genet...
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Genetic buffering mechanisms in SNF2-family translocases
SNF2-family DNA translocases, a large family of ATPases, have poorly defined roles in genomic stability. In a recent study, Feng et al. identified a synthetic lethal interaction between the SNF2 trans...
https://www.cell.com/trends/genetics/fulltext/S0168-9525%2825%2900005-8
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The Vindigni, Krais and
@vermalab-washu.bsky.social
Labsgiving 2024 featured a full turkey, many laughs and lots of multi-cultural food! 🦃
10 months ago
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Finally got on the trend and moved to bluer skies! Though our lab photo got the memo long ago 🧬
10 months ago
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