Warm welcome to Maria and my very best wishes to her as CeMM director - excited for the future of our institute!

Thank you, Marco Demaria (UMCG), for a great #CeMMinar on heterogeneity in cellular #senescence! He shared how senescent cells can both aid tissue repair & drive aging & dysfunction, & how targeting them could support healthy aging. Thanks to our hosts @lderooij.bsky.social & @andre-rendeiro.com

CeMM & ÖAW warmly welcome Maria Rescigno as the new CeMM Director. Maria is a highly accomplished researcher specialized in the understanding of the gut–liver–brain axis. Press info: https://cemm.at/news Photo Gallery: https://cemm.at/about-cemm/picture-galleries/2025 #CeMMLife #Director #ÖAW

Installed #Rstats for the first time in a year - my laptop ran out of battery before I managed to install 2 libraries... 🤕 After working with `uv` for some time, I don't think I can suffer this experience :pain:

One more reason to love Python! Thank you for staying true to your values ❤️

Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

🧭 Colorectal cancer doesn’t follow a single path. Using spatial proteomics on ~500 tumors, we found distinct trajectories from early to late stage, involving the whole tumor microenvironment and its metabolic state. 📄 Preprint: arxiv.org/abs/2510.05083 #SpatialBiology #CRC #ImageBasedProfiling 1/5

New work from Iva Buljan @ivabuljan.bsky.social in our lab! We mapped how human tissue architecture changes with age using ~25k histology slides from 983 donors. This is the first body-wide atlas of human microanatomy. 📄 Preprint: www.biorxiv.org/content/10.1...

We will have our next community meeting on Tuesday, 2025-10-14 at 18:00 CEST! Yimin Zheng will be presenting on LazySlide, a Python framework for whole slide image (WSI) analysis. (Zoom registration link and more information in thread!) 🧵

The LBI-NetMed in Vienna is looking for an Administrative Manager to power our research operations. Key role in finance, HR, and partner coordination. Apply here: lbg.ac.at/news/adminis... #ResearchJobs #ScienceAdmin #LBINetMed #Vienna #JobAlert

Great to be at the 2025 @OeGMBT meeting in Innsbruck and hear the diverse research made by the local community, in particular by the young researchers who presented their work. Thank you to the organizers, and to Markus Mandl for the invitation to talk!

CAR T cells showcase the enormous potential of cell therapies, but often fail due to lack of evolutionary optimization. Today in @nature.com , we use #CELLFIE to engineer cell therapies at scale and share the largest resource of CRISPR screens in CAR T cells. www.nature.com/articles/s41...

Congratulations to Lisa Kleissl in our group, who won the best short talk award at the FEBS Advanced Course on Immunology, metabolism and ageing in Matrei am Brenner, Austria!

So, right now, the only reliable way to diagnose endometriosis is with exploratory surgery. But finally, real scientists (instead of male scientists), are on the job & of course they’ve identified multiple markers in menstrual blood that point to noninvasive testing. www.science.org/content/arti...

, a leading #publichealth concern. @sciimmunology.bsky.social www.science.org/doi/10.1126/...

Exciting FULL PROFESSORSHIP at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: www.maxperutzlabs.ac.at/news/open-po... Come be our colleague!

Thrilled to share that our lab has been awarded an ERC Starting Grant for QUANTAGE! 🎉 We will build a quantitative framework of tissue architecture to bridge molecules, cells, tissues & organs — uncovering how aging unfolds and disease begins.

Our group is in Gumpoldskirchen, Austria, for our first lab retreat! It is a fantastic opportunity to get together and discuss our research projects, share ideas, and engage in some team building. A big thank you to everyone in the team, who together make it a privilege and honor to do this job.

Yimin Zheng from our lab presented LazySlide, our framework for whole-slide image analysis, at the Sydney Statistical Bioinformatics Seminar Series 🎉 📺 Watch the talk: www.youtube.com/watch?v=PZAp... 🔗 More from the awesome series: www.youtube.com/@SydneyDataS... Big thanks to the organizers!

Since search is dead, how soon do you think Google Scholar is headed for the Google Graveyard? I'm betting it's soon, and academia is NOT prepared

Have $10M and want to cure some diseases? It costs ~$1B to invent a new medicine…but $10M buys you Project Encore, to see if ANY existing drug might be repurposed for ~100 diseases that have no treatments. Contact me - be a hero for desperate patients! docs.google.com/document/d/1...

🚨 We're hiring! The Rendeiro Lab @cemm.oeaw.ac.at is looking for a data scientist or software engineer to work on open-source tools for spatial, histological & multimodal data. Ad: www.nature.com/naturecareer... More info: rendeiro.group

Join two powerhouses of research driving innovation in artificial intelligence and biomedicine in Vienna! My group will be recruiting a PhD student to continue and extend our work on spatially resolved study of aging via principled computational approaches: rendeiro.group apply.cemm.at

Excited to share a new preprint from the lab with @ryandhindsa.bsky.social ! www.biorxiv.org/content/10.1... Led by @sherrynyeo.bsky.social, @erinmayc.bsky.social, and friends, we continue our journey to find viral DNA in our favorite place-- the overlooked and discarded reads in existing data! 1/

⭐ CeMM is proud to have supported #KinderuniWien together with @oeaw.bsky.social again this year! We created a fun online video, quiz & game to show children how wounds heal & the immune system protects us. Watch it below 👇 🎥 “Die Blutbaustelle - Helfer im Einsatz!” (in German) 🔗

I received some old microscopy slides from the 1800s, when at-home microscopes made it possible to look at hidden worlds of diatoms, polycystina, and other teeny tiny things. I made this website so people today can take a look too: microspeci.men Enjoy! #scienceisforeveryone #microscopy #HistSci

LazySlide 🦥 just hit 100 GitHub stars! 🎉 Our free, open-source framework is making whole slide analysis easier than ever. Built on scverse 🐍, it handles everything from tissue segmentation to multi-omics workflows 🤹 & deep learning 🏋️. Big thanks to the community! www.biorxiv.org/content/10.1...

📢 Announcing the MOPITAS Autumn School on Spatial Transcriptomics Data Analysis – taking place November 12–14, in Munich. Don't miss this excellent opportunity to deepen your expertise in data science and multi-OMICS analysis - especially as a PhD student in the data science community.

This was interesting: How should Portuguese Americans be classified? www.theatlantic.com/ideas/archiv...

We finished the week by welcoming @lochlanfennell.bsky.social (UniSC 🇦🇺) for an Impromptu Seminar on the spatial tumour–immune microenvironment in #ColorectalCancer 🧬 Thank you, Lochlan, for an insightful presentation & engaging discussion, & to our host, CeMM PI @andre-rendeiro.com!

🚨 New preprint: The Spatial Atlas of Human Anatomy Jiwoon Park et al @ Chris Mason's lab present the first multimodal, subcellular-resolution reference of human tissues across organs. 15M cells from >100 donors profiled with CosMx, Xenium, GeoMx, snRNA-seq and more: www.biorxiv.org/content/10.1...

🚨 3 days left to apply! Join us at CeMM (Vienna) to work on AI + computational pathology projects like LazySlide. Amazing team, H100 GPUs, real impact. Apply now: cemm.at/join-cemm/op...

🚨 We are recruiting at CeMM! If you're excited about tools like LazySlide and want to work at the interface of computational pathology, AI, and molecular medicine, check out the CeMM International Postdoc Program. cemm.at/join-cemm/op...

🔬 Whole slide histopathology images are a goldmine for tissue biology and diagnostics - but too often locked away in inaccessible formats or tools. In our new preprint, we introduce LazySlide: an open-source, modular, and interoperable framework. www.biorxiv.org/content/10.1...

Today we had the pleasure of hosting Roman Praschberger (@i-med.ac.at) at #CeMM for an Impromptu Seminar hosted by @andre-rendeiro.com. Roman shared how rare disease genetics & #SingleCell sequencing can uncover neuronal resilience pathways. Thanks for the inspiring talk!

It’s Friday! 🔍Discover the #EquationsForLife from @andre-rendeiro.com's Group: using #LinearRegression & deep learning, they created “tissue clocks” that predict biological age from images & blood!🧬 👉Read more: tinyurl.com/CeMMRR2024-R... #CeMMResearchReport2024

Welcome AITHYRA!

Pujol Gualdo, N., Džigurski, J., Rukins, V. et al. Atlas of genetic and phenotypic associations across 42 female reproductive health diagnoses. Nat Med (2025). doi.org/10.1038/s415... ^^ super important research and some great insights and polygenic risk scores with broad applicability

How well do CT scans predict the aggressiveness of early lung lesions? 🫁 Imaging >60 proteins in >2M cells, we compare CT and histology classes in very early lesions, and show fibrosis and EMT-driven changes missed by CT. #lungcancer #cancerresearch doi.org/10.1101/2025...

Excited to announce that the Rendeiro Lab Manual is now open source! Inspired by other labs, the information we need to work efficiently and collaborative is now available to everyone: rendeiro.group/lab-manual/ (source available here: github.com/rendeirolab/...)

🚨 Only a few days left to apply! 🚨 Join our interdisciplinary lab through the CeMM PhD Program! We're hiring PhD students in computational and systems biology. 📄 Learn more & apply: apply.cemm.at

Less than a week less to join our innovative team to advance network medicine research. Apply now! 🧬🚀🎓 www.nature.com/naturecareer...

Yimin's paper on a a novel visualization paradigm and implementation of cross-layout visualizations is now published in the journal Genome Biology (genomebiology.biomedcentral.com/articles/10....). Check it out at github.com/Marsilea-viz...

HIRING: We offer several PhD student positions in the CeMM PhD Program. Looking for 3 types of candidates: experimental systems biology in cancer & immunity; bioinformatics & biomedical ML/AI; tech-dev & bioengineering. Join an a highly collaborative lab in molecular medicine. Details below (1/4)

Thank you to our friends @gmivienna.bsky.social for the very nice and on point Arabidopsis histology-inspired season greetings, happy holidays!

Proud of Iva Buljan, PhD student in the lab, who gave a talk and presented a poster at the inaugural meeting of the European Society for Spatial Biology in Berlin, Germany last week!

Iva Buljan from the lab of @afrendeiro.bsky.social presents the analysis of Genotype-Tissue Expression Project deriving tissue age indicators and identifying interesting mismatches between tissue and chronological age Preprint: www.biorxiv.org/content/10.1... #ESSB2024

Exciting opportunity: The Ludwig Boltzmann Institute for Network Medicine in Vienna is offering interdisciplinary PhD positions. Join our innovative team to advance network medicine research. Apply now to be part of groundbreaking discoveries! www.nature.com/naturecareer... 🧬🚀🎓

Ejner Molten @ Austrian personalized medicine conference: data [harmonization, sharing, annotation, ...] is the largest barrier to personalized medicine implementation in Europe