#ICYMI ImmunoHorizons is excited to share a Special Collection focused on avian influenza, featuring 3 reviews on factors impacting emergence and spread #OneHealth, characteristics of current H5N1 strains, and a method for vaccine design. Read more: ow.ly/6HN550XSZop.

When comparing salivary IgA antibody levels in those with vaccine-only vs vaccine-and-infection immunity, researchers found that IgA levels to spike and RBD are high in those with hybrid immunity but low in those with vaccine-only immunity. Read more: ow.ly/Xg8W50XNcci.

Are you passionate about immunology and ready to gain hands-on advocacy experience? The AAI PPFP 2026-27 is about more than understanding science policy—it's about making scientists heard. https://www.aai.org/Public-Affairs/PPFP?utm_source=bsky&utm_medium=social&utm_campaign=PPFP_2026#gsc.tab=0#gsc

AAI Member Dr. Elizabeth Jaffee from Johns Hopkins Medicine shared with #ImmunologyExplained the powerful story of how her research is changing outcomes for patients with pancreatic cancer. Learn more and watch the video: ow.ly/mKx550XyhEC.

Researchers sought to determine if pre-existing immunity to Cas9 from S. aureus or S. pyogenes was present or augmented in people with cystic fibrosis (CF), as a cure for #CF will likely require a gene therapy approach. Learn more in ImmunoHorizons: ow.ly/9MUj50XsYlK.

Researchers found that exogenous type I interferons, a major downstream product of STING activation, also upregulate CCL22 in cancer cells via a STING-dependent mechanism and that exogenous IFN-β can directly activate STING. Learn more in ImmunoHorizons: ow.ly/C11i50Xmw7h

The synergistic activity of LIGHT with other classical cytokines was observed to regulate transcription in pulmonary fibroblasts and suggests the involvement of LIGHT in shaping fibroblast phenotypes observed in chronic lung disease. 🔗 ow.ly/pGOn50Xmwlq. #OpenAccess

Researchers found that exogenous type I interferons, a major downstream product of STING activation, also upregulate CCL22 in cancer cells via a STING-dependent mechanism and that exogenous IFN-β can directly activate STING. Learn more in ImmunoHorizons: ow.ly/C11i50Xmw7h

🎃 Happy Halloween! Ever wondered what your immune cells would wear to a costume party? 🚑 Neutrophil as an EMT: First responder on duty! 🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision! What do you think each immune cell would wear for Halloween?

#DYK We published one of the 6 spookiest discoveries of the year according to @zmescience.bsky.social? As a ghost passes through a wall, the parasitic work Schistosoma mansoni can pass through your skin without being detected. Read more: ow.ly/yIUS50Xl7h3. 📘 ow.ly/189i50Xl7h4

CHPE and metformin can modulate immune responses and improve gland function in mouse model of Sjögren’s disease via interaction with antigen-binding grooves of MHC Class II, with effectiveness varying by sex and age academic.oup.com/immunohorizo... @immunohorizons.bsky.social

Get ready for #IMMUNOLOGY2026™! We're heading to the vibrant city of Boston, MA. Prepare for groundbreaking science, incredible networking, and an unforgettable experience. Don't miss your chance to be part of the #immunology community! Learn more: immunology2026.aai.org/abstracts.

🚀 New from AAI: Immunology Explained — a hub for clear, evidence-based insights into how the immune system protects health. Check it out: immunologyexplained.aai.org Find and follow Immunology Explained on TikTok, Facebook, Instagram and YouTube #ImmunologyExplained

An essential conversation during #PeerReviewWeek! We hosted the webinar "How to Be the Reviewer You Want to Have," presented by Dr. Gail A. Bishop, EIC of @jimmunol.bsky.social. It's a key topic for graduate students and post-docs. Watch now: ow.ly/mAXQ50WZ1kH #TBT #PeerReviewWeek

Boost your career with an AAI Travel Award! Open to AAI members, these awards provide funding to attend #IMMUNOLOGY2026™. Submit your abstract and apply for an AAI Travel Award by the October 15 deadline. Learn more: ow.ly/cBuc50WYhwq.

Joining us on Capitol Hill Sept 30? Meet our exciting lineup of speakers: Dr. James Allison, world-renowned oncology expert, Dr. Elizabeth Jaffee, and cancer survivor Alexis Browning. They will share their expertise and insights on the impact of immunotherapy. RSVP today: bit.ly/AAI-GA-Brief....

Review @immunohorizons.bsky.social The cat’s out of the bag: Toxoplasma gondii provides further insight into myeloid-mediated host defense academic.oup.com/immunohorizo...

New findings provide insight into the dynamics of various immune proteins present in breastmilk and highlight their pivotal roles in determining neonatal immune responses and microbial colonization at early stage. Read all about it: ow.ly/tGcu50W0eG3. #OpenAccess

🚨 IMMUNOLOGY2026™ abstract submissions are now open! Share your groundbreaking research with the global immunology community. Submit your abstract by October 15: immunology2026.aai.org/abstracts

The latest press release for @immunohorizons.bsky.social showcases new research that paves the way for more personalized veterinary care for dogs that could help dog owners make informed decisions that keep their pets healthier longer. Read it in #AAInews: ow.ly/imSg50WMatf.

🔬 Join us for a webinar on Biomarker Selection and Analysis in Clinical Trials on Sept 2, 4-5 PM ET! Featuring Drs. Allan D. Kirk (@dukehealth.bsky.social) and Katherine P. Liao (@harvardmed.bsky.social). Don't miss out and register now: ow.ly/zAOG50WHPy8 #AAIwebinar #clinicalimmunology #immunosky

Aberrant humoral immune responses and intestinal homeostasis in Cd38 Bst1 double knockout mice @immunohorizons.bsky.social academic.oup.com/immunohorizo...

The countdown begins to #IMMUNOLOGY2026™ in Boston, MA! In less than two weeks, you can submit your abstract from September 3 – October 15. Start preparing your research today for a chance to present in Boston! immunology2026.aai.org #immunology #scicomm

Is your lab at risk due to unexpected federal grant terminations? The AAI RESTORE Grants Program offers up to $100K to help you retain personnel & continue critical immunology research. Deadline Aug 28! Share with your colleagues today: ow.ly/4PWF50WxYt4. #ScienceFundingCrisis #SupportResearchers

A parasitic worm suppresses neurons to evade detection. Researchers from @tulanemedicine.bsky.social say isolating the molecules responsible for the suppression could lead to new painkillers for humans. Read more in the latest press release on AAI News: ow.ly/Agot50WCM2E.

Researchers discovered B cell follicles in nurse shark pancreas and saw antigen-specific antibodies were produced in the pancreas following immunization providing insight into how immune surveillance may function in the absence of lymph nodes. Read more: ow.ly/oF6q50WCKbg

🚨 AAI is proud to announce the launch of the AAI RESTORE Grants Program, an $8M emergency funding initiative to support scientists whose immunology-focused federal research grants were abruptly terminated or frozen in 2025. 🔗 ow.ly/rwMU50Wy3Mp #AAIRESTORE

Apply today to participate in the AAI Peer-Review Mentorship Program! This program is designed to provide mentorship from seasoned professionals to develop your skills as a peer reviewer of manuscripts submitted to AAI journals. Learn more: ow.ly/qLyn50WuPxA.

Characterization of extensive diversity in immunoglobulin light chain variable germline genes across biomedically important mouse strains @immunohorizons.bsky.social academic.oup.com/immunohorizo...

@astra-zeneca.bsky.social evaluated acalabrutinib with supportive care vs. supportive care alone in phase 2 clinical studies of hospitalized patients with #COVID19. No safety concerns and no significant benefit of adding acalabrutinib were reported. Read more in IH: ow.ly/gxE250Wa1fS.

Arthritogenic alphaviruses, including #chikungunya and Mayaro, induce CCL4, but the role of CCL4 in disease development is unexplored. Researchers evaluated the effect of CCL4 on Mayaro virus but were unable to find a role for CCL4 or receptor CCR5: ow.ly/RPrJ50Wa1aS.

New findings provide insight into the dynamics of various immune proteins present in breastmilk and highlight their pivotal roles in determining neonatal immune responses and microbial colonization at early stage. Read all about it: ow.ly/tGcu50W0eG3

Human in vitro studies of HIV Nef on TcR proximal signaling have been controversial and have not provided an integrated picture of its impact. New data identifies how Nef impacts Lck in a unique way, triggering it to mis-phosphorylate its substrates. 🔗 ow.ly/Qaen50W0ekG

Enhance your knowledge with the 2025 AAI Intro Course. Join expert faculty, such as Sarah Gaffen @slg1717.bsky.social, a past Deputy Editor of The JI, for a comprehensive overview of the basics of #immunology. Register now to build your repertoire with AAI from July 8-13 in LA! ow.ly/Uf7F50W2TU5

Researchers have identified the role of PTEN, a lipid/protein phosphatase traditionally recognized as a tumor suppressor, in the macrophage phagocytosis of gram-positive bacteria and the development of monocyte subsets. Read their findings in ImmunoHorizons: ow.ly/u7zl50VTUPa.

🔬 Enhance your knowledge from intro to advanced with 2025 AAI Immunology Courses! ➡️ Introductory (UCLA): July 8-13. ➡️ Advanced (Boston): July 27-Aug 1. Build your immunological repertoire and register now: ow.ly/oYyj50VZtYX. #Immunology #AAIcourses

Data suggest that synthetic vaccine adjuvant EMT4™ is suitable to backfill the preclinical #tuberculosis (TB) vaccine candidate pipeline and for the needs to the global community in ending TB. Learn about this exciting development here: ow.ly/3Ayu50VTUGY.

Tissue resident memory T cells play a critical role in cancer immunity, but little is known about their presence in malignant pleural effusions, which are collected to manage symptoms in patients. Researchers address this gap in knowledge with new data: ow.ly/2GOr50VTV4G. #TCells #Immunology

AAI’s Committee on Public Affairs took full advantage of the opportunity for advocacy and education at #IMMUNOLOGY2025. Learn more about the important discussions that took place and how to #TakeAction by writing to your Members of Congress on AAI News: ow.ly/bsSY50VWnuX

Researchers saw significant changes in the antimicrobial and immune proteins present in #BreastMilk throughout the lactation period, providing insights on the roles of immune proteins in neonatal immune responses and microbial colonization. Learn more: ow.ly/L1oP50VTV0r.

Level up your #immunology research! The new AAI Computational Immunology Course covers machine learning, single-cell RNA-seq, spatial transcriptomics & more. Get the computational edge: ow.ly/wkgM50VTTJ2.. #immunology #bioinformatics #datascience

New data suggest iSP1, a STAP-1 derived peptide, could be used as a new therapeutic immunomodulatory agent for #autoimmune diseases. Learn more by reading the full #openaccess article in ImmunoHorizons: ow.ly/6AGk50VTUSq.

Grant rescissions? Stalled research? Job losses? Uncertainty in science funding has real consequences. Tell Congress & support $51.3B+ for NIH! ✍️ ow.ly/20S450VJHkV #AAIadvocacy #InvestInScience #ScienceMatters

Do you have a manuscript on #autoimmunity you would like to showcase in the upcoming #autoimmunity special series? Learn how to submit your manuscript to share cutting-edge research and impactful findings with #immunology colleagues: ow.ly/sbz250VISU5.

New #clinical data found that CD8 T cells contribute to protective immunity against #chlamydia in women, specifically showing that the frequency of IFN-gamma producing CD8 T cells was inversely associated with C. trachomatis bacterial load. Learn more: ow.ly/uFkg50VISvN

#ICYMI: MK-6194, an interleukin-2 mutein that selectively activates regulatory T cells, was evaluated for safety, pharmacokinetics, immunogenicity, and pharmacodynamics. The findings support MK-6194 as a potential treatment for #autoimmune disorders. 🔗 ow.ly/pwQm50VISmA

ImmunoHorizons (IH) is a fully #OpenAccess, peer-reviewed journal committed to advancing the knowledge of immunology and immunology education. Learn more about why you should publish in ImmunoHorizons today: ow.ly/BgxV50VEMTY.

Decades of research in the laboratory, followed by large-scale studies in thousands of human volunteers, ensures that vaccines are thoroughly researched and safe to use. Learn more: ow.ly/Ff9B50VEIR7. #ImmunologyExplained #Vaccines

ImmunoHorizons invites you to submit a manuscript for a special series on #autoimmunity that will showcase cutting-edge research and advances, offering an opportunity to share impactful findings. Learn more and submit today: ow.ly/WM4c50VEMJ6.

⌛ The countdown to #IMMUNOLOGY2025 is on! Get ready for the meeting by listening to @aai.org President Dr. Stephen Jameson and @immunohorizons.bsky.social Editor-in-Chief Dr. Bonnie Dittel discuss the highlights of this year's program: bit.ly/3Rs5zY1 #AAI2025