Today’s action to weaken the birth-dose recommendation for the Hepatitis B vaccine disregards data supporting the effectiveness of the Hepatitis B vaccine, and creates confusion for parents about how best to protect their newborns. Full statement: spr.ly/633227f3XE

THIS IS HUGE! Researchers at The Jackson Laboratory and UConn Health have successfully discovered a molecular switch that can actually SHUT DOWN cancer growth signals and STOP tumor growth at the RNA LEVEL. The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. 🧪🧵⬇️

Our latest work on targeting the poison exon in #RNA #splicing factor TRA2B in #cancer reveals a role for this non coding transcript and opportunities for targeting splicing factor levels across multiple tumor types rdcu.be/d90Ra #RNAsky @jacksonlab.bsky.social

www.cell.com/cancer-cell/... Such a cool paper!!!

This is a cool story - spatial proteomics to identify over-expressed pathways (type I IFN & JAK/STAT) proposing new therapies (JAKi) for Toxic Epidermal Necrolysis 🌟 Discovery science translated into clincial benfit. Love it! 🌟 #MedSky 🧪 #ImmunoSky #dermatology www.nature.com/artic...

"Here, we identify an alternative splicing isoform of human PD-1, which carries a 28-base pairs extension retained from 5′ region of intron 2 (PD-1^28), is expressed in peripheral T cells and tumor infiltrating lymphocytes." #Immunology #Immunotherapy www.nature.com/articles/s41...

Complementation of a human disease phenotype in vitro by intercellular mRNA transfer https://www.biorxiv.org/content/10.1101/2024.11.06.622258v1