Hans schoofs
@hansschoofs.bsky.social
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Post-doc at NKI-AVL - van Rheenen group - Two photon enthusiast- Vascular biologist-
pinned post!
This work would not have been possible without our many collaborators who provided reagents, lines and much needed support!
@ruibenedito.bsky.social
, M. Jeansson,
@brittae.bsky.social
, D. Vestweber, K. Gängel, O. Friedrich, J. van Buul, P. Saharinen, R. Smith and M. Majda and many others!
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8 months ago
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This beautiful work from the lab in Uppsala @taijamakinenlab.bs made it to the cover ! Happy to be part of it ! Congrats again to the first author Marle Kraft ! Stunning images
add a skeleton here at some point
4 months ago
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Extremely grateful to be granted a two year post-doctoral fellowship by
@embo.org
to study the earliest phases of mutant to malignant cell transition during breast cancer initiation using intravital microscopy. Thank to
@vanrheenenlab.bsky.social
for the immense support!
@nkinl.bsky.social
5 months ago
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reposted by
Hans schoofs
Hao Yin
5 months ago
An imbalance of Angiopoietin ligands & endothelial TIE2 hyperactivation underlies PI3KCA-driven
#VenousMalformation👹
⏫
#MuralCell
Angpt1 ⏬
#EndothelialCell
Angpt2
#SciArt
@hansschoofs.bsky.social
‬@taijamakinenlab.bsky.social‬
@natcardiovascres.nature.com
2025
www.nature.com/articles/s44...
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reposted by
Hans schoofs
Makinen lab - Lymphatic Biology and Pathology
6 months ago
Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations. Read our work in ‪@natcardiovascres.nature.com by Marle Kraft et al.
rdcu.be/enhST
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Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations
Nature Cardiovascular Research - Kraft et al. identify TIE2 activation as a key driver of PIK3CA-related venous malformations and demonstrate that inhibiting TIE2 signaling can suppress the growth...
https://rdcu.be/enhST
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reposted by
Hans schoofs
Van Rheenen Lab
6 months ago
📣New Preview out today
@cp-devcell.bsky.social
by Maria Azkanaz & Dimitrios Laskaris, describing the paper by Banjac et al
@kimbakjensen.bsky.social
lab! Stemness in flux: Dissecting intestinal crypt organization with multimodal approaches. Check it out here 👇
authors.elsevier.com/c/1l2MG5Sx5g...
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• Happy to announce that our paper in
@nature.com
is finally out! Thanks to the perseverance of
@taijamakinenlab.bsky.social
and our many collaborators we finally pulled it off! A small đź§µ
www.nature.com/articles/s41...
Laymen video:
www.nature.com/articles/d41...
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Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium - Nature
Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result from continuous...
https://www.nature.com/articles/s41586-025-08724-6#Abs1
8 months ago
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After 5 years my scientific chapter in Uppsala is coming to an end. Two weeks ago I have successfully defended my PhD thesis at the Mäkinenlab. Big thanks to Taija for being a true mentor and to Holger Gerhardt for acting as my opponent and critically assessing my work.
10 months ago
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