Read more about ASAP's new pan-coronavirus antiviral designed to keep us safe from future pandemics!

"If funding isn’t restored soon, Chanda says, promising antivirals will be lost, and the world will be defenseless against the next pandemic." cen.acs.org/pharmaceutic...

ASAP is incredibly proud to work with superstar antiviral discovery scientists at Mount Sinai: Briana McGovern, Meg Gordon, Dr. Kris White, Dr. Suazo, and Jared Benjamin, among others! Read about their important work here: health.mountsinai.org/blog/stories...

Read about the scientists on the front lines working tirelessly to make antivirals to prevent future pandemics in the Kris White lab at Mount Sinai: health.mountsinai.org/blog/stories...

Next up in today's Antiviral Drug Discovery Open Science Forum is Peter Sjö (@dndi.org) and Annette von Delft (@cmd.ox.ac.uk) of ASAP talking about DNDi-6510, the preclinical candidate from the COVID Moonshot! asapdiscovery.org/forum

First up in today's Antiviral Drug Discovery Open Science Forum is Jeroen Kruter and Ingrid de Visser-Kamerling of INFECTA: infecta.org asapdiscovery.org/forum/

Join us for the Wed 18 Jun Antiviral Drug Discovery Open Science Forum at 11A ET to hear from Ingrid de Visser-Kamerling and Jeroen Kruter of INFECTA on Controlled Human Infection Models, as well as Annette von Delft and Peter Sjö of ASAP on the discovery of DNDi-6510! asapdiscovery.org/forum/

Next up in today's Antiviral Drug Discovery Open Science Forum is Juan C. de la Torre of CAMPP @scripps.edu talking about antiviral discovery for mammarenaviruses. asapdiscovery.org/forum

First up in today's Antiviral Drug Discovery Open Science Forum is Warren Thompson ASAP @diamondlightsource.bsky.social showing automated fragment progression capabilities that Diamond Light Source users will soon be able to access! asapdiscovery.org/forum/ www.diamond.ac.uk/Instruments/...

Join today's Antiviral Drug Discovery Open Science Forum at 11A ET to hear Warren Thompson (‪ASAP @diamondlightsource.bsky.social‬) discuss robotic fragment progression and Juan Carlos de la Torre (‪CAMPP @scripps.edu‬) present strategies to combat human mammarenaviruses: asapdiscovery.org/forum/

ASAP is incredibly proud to help pioneer new ways of making medicines globally affordable and accessible for all.

ASAP, OpenADMET (@openadmet.bsky.social), and Polaris Hub (@polarishub.io) are hosting a virtual meeting on Wed 30 Apr to learn from top performers in our recently concluded blind modeling challenge. To join or learn more about these efforts, check out: www.linkedin.com/feed/update/...

This Wed 16 Apr at 11.00A ET, the Antiviral Drug Discovery Open Science Forum features talks on Dengue antiviral discovery and development from Xuping Xie (@utmbhealth.bsky.social) and Darlene Chen (@novartis.bsky.social) of the UNAPP AViDD! asapdiscovery.org/forum

Massive credit to all members of @asapdiscovery.bsky.social :- drug discovery is a massive team sport. Especially the chemists at Enamine working through the war.

ASAP lead med chemist Ed Griffen (@griffen-ed.bsky.social) and @dndi.org Access Leader Pascale Boulet explain how ASAP is using patents to serve the common good by enabling globally equitable and affordable access to medicines in this feature in @cenmag.bsky.social: cen.acs.org/pharmaceutic...

📢Important announcement! Today, the @asapdiscovery.bsky.social consortium disclosed the structure of our preclinical candidate, ASAP-0017445, a promising broad-spectrum antiviral with potent activity against SARS-CoV2 and other viruses belonging to the same family. (1/10)

Exciting news! The structure of the new MERS-CoV/SARS-CoV-2 oral antiviral developed by the ASAP Discovery consortium has been disclosed today. Read this thread for all the details:

If you're attending the American Chemical Society (ACS) meeting either physically or virtually, tune in to today's talk disclosing ASAP's new oral antiviral candidate aiming to help protect against future pandemics.

Three days to go until the unveiling of our MERS-CoV/SARS-CoV-2 oral antiviral candidate for preclinical development!

✨Another symposium session reveal✨ Featuring Max Morgan and @griffen-ed.bsky.social, this session features speakers inventing and actively implementing new strategies that centre open science and collaboration to drive drug discovery! Register here: conscience.ca/symposium2025

5 weeks to go! 🚀 Dr @griffen-ed.bsky.social is presenting at the ACS Spring Meeting & Expo. Talk Title; “Discovery of non-peptidomimetic oral combined MERS and SARS-CoV-2 anti-virals." @asapdiscovery.bsky.social @acs.org #ACSSpring2025 Click to register 🔗 www.acs.org/meetings/acs...

5 weeks to go🚀 @griffen-ed.bsky.social is presenting at the @conscience-network.bsky.social Symposium. Talk Title; "Balancing Open Science and Intellectual Property to Discover and Develop Medicines” @asapdiscovery.bsky.social Register now: conscience.ca/symposium202...

Lead medicinal chemist Ed Griffen (@griffen-ed.bsky.social) will be disclosing the new ASAP MERS-CoV/SARS-CoV-2 oral antiviral at @acs.org on Tue 25 Mar! Tune in to this virtual session to hear about its discovery and development! acs.digitellinc.com/live/34/sess...

Next up for our Antiviral Drug Discovery Open Science Forum Jingyue Ju (Columbia University) of the Metropolitan AntiViral Drug Accelerator (MAVDA), discussing inhibitors of RNA synthesis for coronaviruses and other viruses of pandemic potential. Check out his talk here: openantivirals.org

Tem Morrison (University of Colorado School of Medicine) is up next in this month's Antiviral Drug Discovery Open Science Forum, discussing the debilitating effects of Chikungunya virus (CHIKV) and the high need for antivirals. Tune in now, or watch his presentation later: openantivirals.org

Our team is having fun trying out the binding pose challenge! Check it out below, the organisers have done a great job making the data easy to access and understand!

⚡ The intermediate leaderboard for the antiviral challenge is now live! 👀 See how you placed: antiviral.polarishub.io The challenge officially ends on March 10th, but there's one last leaderboard update before the final results. Submit before midnight on Feb 26th! polarishub.io/competitions

This month's Antiviral Drug Discovery Open Science Forum kicks off with Margaret Kielian (@einsteinmededu.bsky.social), part of the Antiviral Countermeasures Development Center (AC/DC AViDD), focusing on developing antivirals to alphaviruses! Join now, or watch later: openantivirals.org

Next up at the Antiviral Drug Discovery Open Science Forum is Charles Craik (UCSF QCRG AViDD Center) talking about the discovery of broad-spectrum coronavirus Mpro inhibitors! openantivirals.org

First up in today's Antiviral Drug Discovery Open Science Forum is Sara Cherry, who works with both CAMPP and READDI-AC AViDD Centers to discover antivirals for emerging RNA viruses! openantivirals.org

Working on predictive models for drug discovery? Here's your chance to see how well your models actually work! Together with @polarishub.io and OpenADMET, we've launched a blind prospective challenge to see how well predictive models for drug discovery can actually predict real drug discovery data!

Join us for the next Antiviral Drug Discovery Open Science Forum on Wed 15 Jan at 11A ET as Sara Cherry (CAMPP) and Charles Craik (UCSF QCRG) discuss antiviral discovery for coronaviruses and emerging RNA viruses! openantivirals.org

If you missed previous Antiviral Drug Discovery Open Science Forum talks, you can find videos of all of them online here: asapdiscovery.org/forum/#past-...

Next up in today's Antiviral Drug Discovery Open Science Forum is Mei Hong (MIT) of the QCRG AViDD Center, talking about solid state NMR of the SARS-CoV-2 E protein: asapdiscovery.org/forum/#sched...

First up in today's Antiviral Drug Discovery Open Science Forum is Peter Brown of UNC Chapel Hill and READDI-AC talking about the discovery of covalent chemical probes for CHIKV nsP2 protease: asapdiscovery.org/forum/#sched...

Today's Antiviral Drug Discovery Open Science Forum starts at 11A ET and features Peter Brown of the READDI-AC AViDD Center and Mei Hong of the UCSF QCRG AViDD Center talking about CHIKV and SARS-CoV-2! asapdiscovery.org/forum/#sched...

If you woke up today and thought, "hm, I'd really like to compete against the best and brightest in a robust, friendly drug discovery challenge that pushes the envelope of what open science is capable of," then we have great news for you!

We're excited to work with @omsf.io OpenADMET and @polarishub.io to bring you this blind predictive modeling community challenge! If you're developing predictive models for drug discovery---potency or ADMET---here's your chance to test them prospectively on real discovery data from ASAP!

🧵 We highlighted some orgs that are helping advance open science through the release of new data: - @asapdiscovery.bsky.social for antivirals - OpenADMET consortium - @recursionpharma.bsky.social and their [rxrx.ai](rxrx.ai) collection of phenomics datasets + the latest release - RxRx3-core

The great Diamond team, part of the @asapdiscovery.bsky.social and @covid-moonshot.bsky.social backbone.

Did you miss one of our Antiviral Drug Discovery Open Science Forum talks? Check out all of the talks archived here to learn more about drug discovery for pandemic preparedness! www.youtube.com/@AViDD-OSF/v...

Our predecessor project, the COVID Moonshot (@covid-moonshot.bsky.social), is now on Bluesky! Give them a follow for updates on that project!

ASAP lead medicinal chemist Ed Griffen (@griffen-ed.bsky.social) is talking about ASAP's IP strategy to enable global equitable and affordable access in today's Antiviral Drug Discovery Open Science Forum: asapdiscovery.org/forum

Tune in Wed 20 Nov at 11A ET for our Antiviral Drug Discovery Open Science Forum to hear Ed Griffen (@griffen-ed.bsky.social) [MedChemica @medchemica.bsky.social] and Pascale Boulet [DNDi @dndi.bsky.social] discuss enabling affordable access with creative IP agreements! asapdiscovery.org/forum/

The ASAP Discovery Consortium is now on Bluesky! Check out our open science pipeline for antiviral drug discovery here: asapdiscovery.org