Lingzhong Fan
@lingzhongfan.bsky.social
📤 140
📥 818
📝 17
https://sites.google.com/view/fanlab
reposted by
Lingzhong Fan
21 days ago
We would frame this as homologous specialization between these species but not convergent evolution, given the potential dorsal pathway prototype in their common ancestor. More to come!
add a skeleton here at some point
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Lingzhong Fan
Cedric Boeckx
21 days ago
Very interesting new work by
@lingzhongfan.bsky.social
& colleagues, identifying an arcuate fasciculus homolog in the marmoset brain — with implications for the evolution of the neural scaffold supporting vocal communication 🧪🧠
www.pnas.org/doi/abs/10.1...
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Homologous specialization of arcuate fasciculus ventrolateral frontal connectivity in marmosets and humans | PNAS
The arcuate fasciculus (af) is a crucial dorsal pathway underpinning human language, yet its weak frontal connectivity in macaques—the standard pri...
https://www.pnas.org/doi/abs/10.1073/pnas.2600429123
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Mapping the coupling between tract reachability and cortical geometry of the human brain
www.nature.com/articles/s41...
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Mapping the coupling between tract reachability and cortical geometry of the human brain - Nature Communications
Li et al. introduced tract-geometry coupling (TGC) to quantify the coupling between white matter tracts and cortical geometry in the human brain, shedding light on how the brain’s wiring and shape evo...
https://www.nature.com/articles/s41467-025-62812-9
9 months ago
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Human Brain Mapping | Neuroimaging Journal | Wiley Online Library
onlinelibrary.wiley.com/doi/10.1002/...
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Network Occlusion Sensitivity Analysis Identifies Regional Contributions to Brain Age Prediction
A low-bias, lightweight deep learning model for brain age prediction reveals the human brain's aging process through network occlusion sensitivity analysis, identifying the thalamus's dominant role a....
https://onlinelibrary.wiley.com/doi/10.1002/hbm.70239
12 months ago
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Lingzhong Fan
Hugh Ford
about 1 year ago
New paper out in
@pnas.org
We followed cells migrating along signalling gradients in 3D, and found they collectively behave as a living droplet - a self-propelling fluid that grows.
www.pnas.org/doi/10.1073/...
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reposted by
Lingzhong Fan
about 1 year ago
1/ Really excited to share our new preprint "Arcuate Fasciculus: Evolutionary Convergence in Marmosets and Humans"! Check it out here:
www.biorxiv.org/content/10.1...
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Arcuate Fasciculus: Evolutionary Convergence in Marmosets and Humans
The marmoset is a highly vocal platyrrhine monkey that shares key anatomical and functional features with humans, providing a unique opportunity to illuminate the phylogenetic origins of diverging con...
https://www.biorxiv.org/content/10.1101/2025.04.21.649746v1
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Lingzhong Fan
Cedric Boeckx
about 1 year ago
Possible neural convergence found between marmosets and humans for aspects of the arcuate fasciculus, a white matter tract often seen as critical to support species-specific communicative behavior (new preprint by
@lingzhongfan.bsky.social
and colleagues) 🧪🧠
www.biorxiv.org/content/10.1...
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Arcuate Fasciculus: Evolutionary Convergence in Marmosets and Humans
The marmoset is a highly vocal platyrrhine monkey that shares key anatomical and functional features with humans, providing a unique opportunity to illuminate the phylogenetic origins of diverging con...
https://www.biorxiv.org/content/10.1101/2025.04.21.649746v1
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Lingzhong Fan
bioRxiv Neuroscience
about 1 year ago
Mapping the coupling between tract reachability and cortical geometry of the human brain
https://www.biorxiv.org/content/10.1101/2025.03.31.646498v1
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anytime and anywhere, accessible to all! A wearable repetitive transcranial magnetic stimulation device
www.nature.com/articles/s41...
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A wearable repetitive transcranial magnetic stimulation device - Nature Communications
Repetitive transcranial magnetic stimulation is used to treat various neuropsychiatric but its considerable power consumption and large size limit its potential for broader utility. Here, the authors ...
https://www.nature.com/articles/s41467-025-58095-9
about 1 year ago
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Lingzhong Fan
bioRxiv Neuroscience
about 1 year ago
AIRUS: a simple workflow for AI-assisted exploration of scientific data
https://www.biorxiv.org/content/10.1101/2025.02.23.639768v1
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reposted by
Lingzhong Fan
Bence Ölveczky
about 1 year ago
Excited to present the latest from the lab out today in Cell
www.cell.com/cell/fulltex...
. See Thread! 1/8
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This Week in The Journal | Journal of Neuroscience
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This Week in The Journal
Genes Determine Cortical Connectivity Heterogeneity Deying Li, Yufan Wang, Liang Ma, Yaping Wang, Luqi Cheng et al. (see article e1510242024) Genetic information guides how the neural tube develop...
https://www.jneurosci.org/content/45/7/etwij45072025
over 1 year ago
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Lingzhong Fan
bioRxiv Neuroscience
over 1 year ago
Connectome-seq: High-throughput Mapping of Neuronal Connectivity at Single-Synapse Resolution via Barcode Sequencing
https://www.biorxiv.org/content/10.1101/2025.02.13.638129v1
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reposted by
Lingzhong Fan
bioRxiv Neuroscience
over 1 year ago
Comparative molecular landscapes of immature neurons in the mammalian dentate gyrus across species reveal special features in humans
https://www.biorxiv.org/content/10.1101/2025.02.16.638557v1
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reposted by
Lingzhong Fan
Andreas Horn
over 1 year ago
I am hiring: PhD students, postdocs, admin personnel. Email me if you know somebody that may be interested in joining us in Cologne! 👇👇 Please RT for reach! 🙏🙏
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Ignoring the cerebellum is hindering progress in neuroscience: Trends in Cognitive Sciences
www.cell.com/trends/cogni...
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Ignoring the cerebellum is hindering progress in neuroscience
Traditionally considered a motor structure, the cerebellum has been shown to play a key role in several cognitive functions. However, for decades, the cerebellum has been largely overlooked and even d...
https://www.cell.com/trends/cognitive-sciences/fulltext/S1364-6613%2825%2900004-X
over 1 year ago
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Lingzhong Fan
eLife
over 1 year ago
A combination of machine-learning techniques and more traditional modeling approaches can use the unique patterns of brain activity that evolve over time to predict traits such as age and cognitive ability.
https://elifesciences.org/digests/95125/predicting-individual-traits-from-dynamic-brain-acti…
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Predicting individual traits from dynamic brain activity
A combination of machine-learning techniques and more traditional modeling approaches can use the unique patterns of brain activity that evolve over time to predict traits such as age and cognitive…
https://buff.ly/4aIvSC7
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www.biorxiv.org/content/10.1...
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Baby Open Brains: An Open-Source Repository of Infant Brain Segmentations
Reproducibility of neuroimaging research on infant brain development remains limited due to highly variable protocols and processing approaches. Progress towards reproducible pipelines is limited by a...
https://www.biorxiv.org/content/10.1101/2024.10.02.616147v2
over 1 year ago
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reposted by
Lingzhong Fan
The Innovation
over 1 year ago
New in
@theinnovation.bsky.social
! The Chimpanzee Brainnetome Atlas reveals distinct connectivity and gene expression profiles relative to humans. Wang et al. developed the Chimpanzee Brainnetome Atlas (ChimpBNA) using a connectivity-based parcellation framework.
doi.org/10.1016/j.xi...
#Research
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Congratulations to Deying Li! The work on global connectopies is now live online! Topographic Axes of Wiring Space Converge to Genetic Topography in Shaping Human Cortical Layout
www.jneurosci.org/content/earl...
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Topographic Axes of Wiring Space Converge to Genetic Topography in Shaping Human Cortical Layout
Genetic information is involved in the gradual emergence of cortical areas since the neural tube begins to form, shaping the heterogeneous functions of neural circuits in the human brain. Informed by ...
https://www.jneurosci.org/content/early/2025/01/17/JNEUROSCI.1510-24.2024
over 1 year ago
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Mapping Early Brain Maturation: Anatomical Substrates of Cortical Connectivity Shifts in Neonates
www.biorxiv.org/content/10.1...
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Mapping Early Brain Maturation: Anatomical Substrates of Cortical Connectivity Shifts in Neonates
Understanding the early development of brain connectivity is essential for unraveling the mechanisms of brain maturation. In this study, we utilized diffusion MRI data from 242 term neonates to chart ...
https://www.biorxiv.org/content/10.1101/2025.01.07.627373v1
over 1 year ago
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nbdt.scholasticahq.com/article/1278...
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How to optimize neuroscience data utilization and experiment design for advancing brain models of visual and linguistic cognition? | Published in Neurons, Behavior, Data analysis, and Theory
By Greta Tuckute, Dawn Finzi & 9 more. Neuroscience has made significant progress building large-scale artificial neural network models of brain activity and behavior. This article explores opinions i...
https://nbdt.scholasticahq.com/article/127807-how-to-optimize-neuroscience-data-utilization-and-experiment-design-for-advancing-brain-models-of-visual-and-linguistic-cognition
over 1 year ago
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The Chimpanzee Brainnetome Atlas reveals distinct connectivity and gene expression profiles relative to humans: The Innovation
www.cell.com/the-innovati...
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The Chimpanzee Brainnetome Atlas reveals distinct connectivity and gene expression profiles relative to humans
Chimpanzees (Pan troglodytes) are one of humans' closest living relatives, making them the most directly relevant comparison point for understanding human brain evolution. Zeroing in on the differences in brain connectivity between humans and chimpanzees can provide key insights into the specific evolutionary changes that might have occurred along the human lineage. However, such comparisons are hindered by the absence of cross-species brain atlases established within the same framework. To address this gap, we developed the Chimpanzee Brainnetome Atlas (ChimpBNA) using a connectivity-based parcellation framework.
https://www.cell.com/the-innovation/fulltext/S2666-6758%2824%2900193-0
over 1 year ago
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reposted by
Lingzhong Fan
CLaE
over 1 year ago
PNAS Architecture, constraints, and behavior
www.pnas.org/doi/abs/10.1...
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Architecture, constraints, and behavior | PNAS
This paper aims to bridge progress in neuroscience involving sophisticated quantitative analysis of behavior, including the use of robust control, ...
https://www.pnas.org/doi/abs/10.1073/pnas.1103557108
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reposted by
Lingzhong Fan
Nico Dosenbach
over 1 year ago
The brain’s action-mode is created by a dedicated action-mode network (AMN)
rdcu.be/d5odm
. In the brain’s mode continuum, AMN sits opposite DMN’s default-mode, as yin-yang. AMN might be key in pain, apathy, Parkinson’s. New
@natrevneurosci.bsky.social
w/ Marc Raichle &
@gordonneuro.bsky.social
🧵 ⬇️
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二零二五,唯愿诸位,长歌有和,独行有灯!
over 1 year ago
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reposted by
Lingzhong Fan
Rick Betzel
over 1 year ago
Dissecting origins of wiring specificity in dense cortical connectomes Looks hot! Generative modeling for neural networks -- trying to get insight into the wiring rules of dense connectomes.
www.biorxiv.org/content/10.1...
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Lingzhong Fan
Cristian Gutierrez-Ibañez
over 1 year ago
Very nice peoject on bird brains connectome
bmcneurosci.biomedcentral.com/articles/10....
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The songbird connectome (OSCINE-NET.ORG): structure–function organization beyond the canonical vocal control network - BMC Neuroscience
Background Understanding the neural basis of behavior requires insight into how different brain systems coordinate with each other. Existing connectomes for various species have highlighted brain syst...
https://bmcneurosci.biomedcentral.com/articles/10.1186/s12868-024-00919-3
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www.pnas.org/doi/10.1073/...
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PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
https://www.pnas.org/doi/10.1073/pnas.1506400112
over 1 year ago
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reposted by
Lingzhong Fan
Ardem Patapoutian
over 1 year ago
And here is my condensed guide on how to science: top 5 Rules
add a skeleton here at some point
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Reviewer #2 💕 Topographic Axes of Wiring Space Converge to Genetic Topography in Shaping Human Cortical Layout. Preprint is here:https://doi.org/10.1101/2023.09.06.556618
over 1 year ago
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Soon
over 1 year ago
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reposted by
Lingzhong Fan
Roberto Toro
over 1 year ago
🚨 We’re hiring! 🚨 We're looking for a postdoc for our ERC Synergy project Unfold (
unfold-lab.github.io
). Join our lab at @institutpasteur to model brain morphogenesis! (1/10)
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Hi, 🧠ers
over 1 year ago
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