This review examines the biological, pharmacological, and clinical barriers limiting STING pathway activation in cancer treatment. doi.org/10.1016/j.xi... #Cancer #immunotherapy #clinicaltranslation

In this study, Chen et al. employed multislice electron ptychography to characterize the atomic structure of dense ensembles of nitrogen-vacancy centers in a diamond containing 27 ppm NV centers. doi.org/10.1016/j.xi... #QuantumTechnology #materialscience #research

Zhang et al. suggest the use of a lymphatic endothelial cell conditional knockout model to resolve the link between lymphatic vessel dysfunction and multiple core pathologic mechanisms of IVDD and to further isolate the role of lymphatic vessels. doi.org/10.1016/j.xi... #medicine #research

This review presents a comprehensive overview of recent advances and applications of #largelanguagemodels in battery research, focusing on four key areas: #battery knowledge integration, #materials development, intelligent manufacturing, and battery system management. doi.org/10.1016/j.xi...

This paper examines the individual applications of LNG cold energy utilization, wind-PV power generation with energy storage, and green fuel substitution in data centers. doi.org/10.1016/j.xi... #SustainableTech #energyefficiency #cleanenergy #renewableenergy

This study on β-ethoxy enone-based amine conjugation heralds a significant advancement in chemical biology and pharmaceutical sciences, providing a novel, efficient approach for modifying biologically relevant molecules. doi.org/10.1016/j.xi... #biocompatible #bioconjugation #chemicalbiology

Duan et al. reported a multi-center, case-control study involving 1,659 participants to compare the clinical validity of the methylation-, mutation-, and protein-based classifiers for blood-based early detection of nine types of #cancer. doi.org/10.1016/j.xi... #liquidbiopsy #CellfreeDNA #medicine

Methanobacterium sp. YSL, capable of direct interspecies electron transfer, has been recently found not to be directly involved in iron corrosion. However, it can utilize the hydrogen produced by the oxidation of zero-valent iron for slow growth. doi.org/10.59717/j.x... #MicrobialCorrosion

The review highlights advancements in national prevention efforts, innovative diabetes management models, and emerging technological innovations. doi.org/10.1016/j.xi... #PublicHealth #diabetes

This review commences with a concise overview of the adsorption-desorption mechanism, encompassing the processes of adsorption and uptake in addition to isotherms. doi.org/10.1016/j.xi... #biopolymer #biomimetic #MaterialsScience

Zheng et al. creatively adopt the multi-step solid-state reactions method encapsulating polar π-conjugated [SeO2E] units in a fused quartz tube within SeO2 vapor served as a ‘gaseous solvent’, substituting the classic hydrothermal method for the synthesizing selenites. doi.org/10.59717/j.x...

@theinnovation.bsky.social #webinar: International guidelines on the diagnosis and treatment of nuclear protein in testis carcinoma. Speaker: Yuanzhi Lu, MD Sep. 20, 2025 | 21:00-22:00 (Beijing Time) VooV meeting ID: 630-558-771 Join us this Saturday for more! doi.org/10.1016/j.xi... #medicine

Can an open-source AI bridge global healthcare gaps? Dive into how DeepSeek tackles costs, transparency, and policy hurdles in low- and middle-income countries. doi.org/10.1016/j.xi... #healthcare #artificalintelligence

This work examines how to integrate the principles of complex adaptive systems into the “AI + aviation” paradigm to drive an upgrade in equipment operation and maintenance... doi.org/10.1016/j.xi... #aviation #automation #artificalintelligence

The Biodiversity-Environment-Economy framework illustrates how ecological integrity can drive sustainable prosperity and how that profit can be reinvested to regenerate nature, making conservation a source of opportunity rather than a cost. doi.org/10.1016/j.xi... #biodiversity #environment #economy

In this study, Zhang et al. provide comprehensive guidance on Nuclear protein in testis #carcinoma diagnosis and treatment, covering its epidemiology, pathogenesis, diagnostic methods, therapeutic strategies, BET-inhibitor toxicity, palliative care, and prognostic assessment. doi.org/10.1016/j.xi...

Liu et al. developed a visualization-guided #proteomics workflow that enables the simultaneous labeling and imaging of the cellular thiol proteome. This workflow includes continuous monitoring during peptide enrichment to ensure reliable MS-based site identification. doi.org/10.1016/j.xi...

This study establishes IFI30 as a central regulator of breast cancer progression through dual mechanisms: cancer cell-mediated TAM recruitment via ATF3-CCL5 and macrophage-intrinsic control of PD-L1 expression and polarization. doi.org/10.1016/j.xi... #breastcancer #Immunotherapy

The world’s first pediatric-specific magnetically levitated ventricular assist device, D-miniCor, has been successfully implanted, opening a new avenue of mechanical support for low-body-weight children with end-stage heart failure! doi.org/10.1016/j.xi... #PediatricCardiology #medicaldevices

This commentary highlights recent advancements in asymmetric membrane materials for oil-water separation, with a particular focus on how surface wettability asymmetry and pore structure asymmetry contribute to significantly enhanced separation efficiency... doi.org/10.1016/j.xi... #MaterialsScience

Great News! On Sep. 11, 2025, The Innovation Life, The Innovation Geoscience, The Innovation Materials, The Innovation Medicine, The Innovation Energy was officially indexed by the DOAJ database! We extend our sincere gratitude to our dedicated authors, reviewers, editors, and incredible readers...

Zhang et al. highlighted an encouraging result from a recently published study on gene editing therapy. The study, administered to a neonatal patient with CPS1 deficiency, opens a new window of life for rare disease treatment doi.org/10.1016/j.xi... #genetics #GeneEditing #biotechnology #RareDisease

“Drug Discovery Stories (Volume 2)” offers a coverage of the scientific breakthroughs that have reshaped the modern pharmaceutical landscape. The contributions of pioneers underscore the importance of visionary leadership in advancing drug discovery. doi.org/10.1016/j.xi... #drugdiscovery

@theinnovation.bsky.social #webinar: Carbon-negative transition by utilizing overlooked carbon in waste landfills. Speaker: Chuanbin Zhou, PhD Sep. 13, 2025 | 21:00-22:00 (Beijing Time) VooV meeting ID: 938-631-790 Join us this Saturday for more! doi.org/10.59717/j.x...

The pager explosion in Lebanon is a critical warning: the surge of edge devices is creating new vulnerabilities in urban energy systems. Traditional theories are inadequate, and without swift action, future cities may face frequent blackouts. doi.org/10.1016/j.xi... #UrbanEnergySystems

This study shows that in 2023, a year of unprecedented high temperatures, approximately 178,486 excess deaths were associated with #heatwave exposures, with over half attributed to human-induced warming—climate action and public health strategies are urgently needed. doi.org/10.1016/j.xi... #climate

Can materials train like muscles? Discover a hydrogel that grows stronger with use—powered by bond-breaking chemistry! doi.org/10.1016/j.xi... #materials #Hydrogels #BiomedicalMaterials

Revolutionize healthcare with microneedle technology! Invisible medical records and mRNA delivery in one, offering safe and efficient care to remote areas. Discover how this innovation shapes the future. doi.org/10.1016/j.xi... #HealthcareInnovation #Medicine #technology

Check out our latest issue in @theinnovation.bsky.social !! Volume 6, Issue 9 is now online! www.cell.com/the-innovati... #Sustainability #physics #artificialintelligence #energystorage #medicine #cancerresearch #raredisease #carbonneutral #environmentalhealth #artemisinin

Electric vehicles can provide stable external power and serve effectively as mobile emergency power sources and temporary shelters during extreme weather events, thereby mitigating urban power shortages caused by the disasters. doi.org/10.59717/j.x... #energy #ElectricVehicles #extremeweather

The innovative trimodal thermal energy storage technology solves the problem of heat energy storage through the principles of "popsicle melting + hand warmer + thermos cup." Read more doi.org/10.59717/j.x... #energy #energystorage #Sustainable

Surface modification technologies are addressing core challenges such as weak interfacial bonding, enhancing structural performance, reducing carbon footprints, and driving smart construction and the circular economy. doi.org/10.59717/j.x... #materialscience #carbonfiber #technology

Using a mobile laboratory equipped with Vocus PTR-TOF-MS, Chang et al. report highly time-resolved, ultra-sensitive mobile measurements of atmospheric D4 and D5 across two exploratory pan-region transects in China. doi.org/10.59717/j.x... #airpollution #environmentalscience #industrialpollution

Through systematic resampling of 261 sites spanning four decades (1980s–2020s), Lin et al. quantified the combined impacts of climate warming, soil erosion, and geographic controls on soil organic carbon dynamics across the Tibetan Plateau. doi.org/10.59717/j.x... #geoscience #climate #SoilHealth

@theinnovation.bsky.social #webinar: Satellite observations characterize the impacts of climate change and human activities on permafrost along Qinghai–Tibet Railway. Speaker: Zhengjia Zhang, PhD Sep. 06, 2025 | 21:00-22:00 (Beijing Time) VooV meeting ID: 196-149-944 doi.org/10.59717/j.x...

Dai et al. developed CassavaDB (nature.hainanu.edu.cn/CassavaDB/), a comprehensive multi-omics #database platform dedicated to #cassava. CassavaDB provides #genomic, #transcriptomic, and #metabolomic data along with integrated analysis tools tailored for cassava #research. doi.org/10.1016/j.xi...

Improving the resilience of #renewable #energy to extreme weather is a major challenge for humanity. Building a new power system with high resilience and high recovery capability is a pressing issue that needs to be addressed by the international community and academia. doi.org/10.59717/j.x...

Zhang et al. propose four strategies to decode the significance of psychological stress on #skin, scalp, #hair, and overall well-being. This provides a comprehensive understanding of the stress-skin axis for improved wellness and personalized interventions. doi.org/10.59717/j.x... #stressmanagement

This review explores the opportunities and challenges posed by AI in modern medicine, highlighting its applications in precision healthcare, phenomics, early diagnostics, and personalized treatment. Read more doi.org/10.59717/j.x... #medicine #artificialintelligence #healthcare #research

This review underscores the importance of a multifaceted approach to obesity management, aiming to curb the escalating trend and enhance future interventions and treatments. Read more doi.org/10.59717/j.x... #medicine #obesity #healthylifestyle

This review discusses the application, challenges, and future development directions of artificial intelligence in various branches of life sciences, including zoology, plant science, microbiology, biochemistry...... doi.org/10.59717/j.x... #lifesciences #artificialintelligence #research

Chen et al. propose a new classification system for natural components based on the central dogma of molecular biology, dividing them into two main categories: direct and indirect gene-encoded components. doi.org/10.1016/j.xi... #genomics #bioinformatics #biomedicalresearch #herbalmedicine

In this study, Li et al. summarize the positive feedback between algal blooms and carbon emissions and then highlight macrophyte restoration as a plausible strategy to synergistically alleviate lake eutrophication and carbon emissions. doi.org/10.1016/j.xi... #CarbonEmissions #LakeRestoration

In this study, Zhong et al. investigated how the recent changes in diurnal temperature range resulting from the reversal of asymmetric warming over the past two decades have impacted the vegetation productivity in the extratropical NH northward of 23.5° N. Read more doi.org/10.59717/j.x...

This study shows that DNA-mismatch-repair-deficient cell populations maintain high growth rates despite a high SNV burden of at least 50,000 mutations per cell. In these cells, the INDEL burden plateaus at approximately 16,000 per cell. doi.org/10.1016/j.xi... #SomaticMutations #CellularAging

@theinnovation.bsky.social #webinar: Looking at the Earth from the Sky—Artificial Intelligence Helps Us Understand the Geological Environment. Speaker: Wei Han, PhD Aug. 30, 2025 | 21:00-22:00 (Beijing Time) VooV meeting ID: 340-841-240 Join us this Saturday for more! doi.org/10.59717/j.x...

This paper highlights the urgent need to accelerate research and action on ocean carbon sinks through human intervention, known as the Global Ocean Negative Carbon Emissions Programme, as a vital strategy in global efforts to mitigate climate change. doi.org/10.1016/j.xi... #SustainableOceans

In this study, Chen et al. employed single-cell RNA sequencing to characterize the cellular landscape of 241,837 cells from multiple murine tissues upon Plasmodium berghei ANKA (PbA) infection and after ART treatment. doi.org/10.1016/j.xi... #medicine #malaria #genomics

New in The Innovation Medicine! Escaping the data misuse maze Reorienting medical research toward clinical needs. This article warns against the shift in medical research from clinically driven studies to mechanical data exploitation. Read more doi.org/10.59717/j.x... #medicine #science #Research

Check out the latest issue of The Innovation Medicine!!! Volume 3, Issue 3 is now online! www.the-innovation.org/medicine/art... #medicine #MedicalResearch #DataMisuse #sleepapnea #lungdisease #diabetesmellitus #allogeneictransplantation #reproductivehealth #airquality #CardiovascularHealth