H.pylori nice shot!📸

Myxopapillary ependymoma grossly has a characteristic sausage-shaped appearance. Commonly found associated with the filum terminale, it has a fibrillary glial appearance in a myxoid background. Though previously categorized as CNS WHO grade 1, it is now considered grade 2 #pathsky #medsky #neuropath

Image of the Week! Submitted by: Chhanda Das, M.D., D.N.B. Directory Profile: buff.ly/b7mDAWt Subspecialty: Neuropathology Diagnosis: Pituitary adenoma #Pathology #PathologyOutlines #NeuroPath #PathSky

A 19-year-old man presented with brain tumor at pineal region and cerebellar region. AE1/AE3 : weak staining GFAP: focal near 50% High Ki-67 proliferative index=60% What is it? #neuropath #pathology #pathsky #histology #CNStumor #CNSpath

High grade serous carcinoma in lymphatic vessel at serosa of uterus #gynpath #pathology #histology #gynepath #serouscarcinoma #uterus #ovary

For those of you traumatized by the previous post, a cat picture.

Alport syndrome in middle aged man with hx of hearing impair. Presents with proteinuria, RBC 3-5, UPCR 4, SCr 2.5. Characteristic interstitial foam cells noted. #renalpath #pathsky #nephrology

Honeycomb lung 🫁 #pathology #pathsky @drdeadright.bsky.social @sthanu25.bsky.social @gbosslet.bsky.social @kerrijohannson.bsky.social

#slidearchiveseries history of radical orchiectomy with pure teratoma, serum tumor markers (post-orchiectomy): AFP 537, increased to 469, HCG 2; status post chemotherapy x 4 cycles ➡️ retroperitoneal lymph node dissection #gupath #pathsky

One of the nastiest skin tumours. This one in a vessel enroute to destroy the respiratory membrane diffusion gradient. #MerkelCellCarcinoma #pathology #dermatology #PathSky 👿

#PathSky 79M with a superficial neck mass. Wildly pleomorphic, quite cellular- undifferentiated pleomorphic sarcoma, right? There are basically no mitoses though, the cells have abundant granular-glassy cytoplasm, there is a lot of inflammation, and many bizarre cells have nuclear inclusions.

A cute finding in apocrine metaplasia, do you know what it is? #breastpath #pathsky #pathtwitter #pathx #patologia

#PathSky 43F with a solitary lung mass. Relatively circumscribed, nests and interesting micropapillae of lightly eosinophilic epithelioid cells. Negative for everything except TFE3. Dx?

Schaumann body - calcified inclusion in a giant cell from a colonic biopsy, Crohn’s patient #pathsky #pathology #GIPathology #histology #histopathology

Patient presented with chronic anemia Bone marrow biopsy was performed. +PAS +CD68 #pathsky #skypath #hemepath #pathology #hemato

3. Disseminated histoplasmosis If you can spare a moment, please add a teaching point about this infection in the comments @germhuntermd.bsky.social #pathology #pulmpath #pathsky #pathbugs #crittersonbluesky

Adrenal necrosis GMS and PAS stains show small uniform oval, narrow based budding yeasts. Dx. Adrenal histoplasmosis #adrenalgland #histology #pathsky #histoplasmosis #skypath #pathology #idpath

The wording of this diagnosis caught my eye in an old ppt. 32M h/o abd pain and diarrhea after ending steroid therapy for lupus. Histology shows suppurative inflammation limited to the submucosal layer. Phlegmonous enteritis is the given dx, though that seems to be an outdated term. #gipath #pathsky

Metastatic malignant melanoma at groin node #pathsky#pathology #histology #melanoma #dermpath

To narrow down the differential, I'd guess: CD4, CD8, CD163, ALK, and EBV.

What is the cause of this washed out understaining artifact? It appears randomly and affects only a few biopsies in the batch. #histologyprotocols #medicine #science #pathology #histology #research #histotechnologists #histologysupervisors

Cute little asteroid body #pathsky #pathology #histology #histopathology

Acute promyelocytic leukemia, Giemsa stain #pathsky #medsky #pathology #oncology #hemepath

Nodular lymphocyte predominant Hodgkin lymphoma exhibiting characteristic PD1+ T-cell rosettes around tumor cells #Pathsky #Pathology #Hemepath

Tight clustering of megakaryocytes (arrow) with dysplastic features (irregular, bulbous nuclei) suspicious for PMF. Would love a reticulin stain to assess for presence of fibrosis to further support a dx of PMF! #pathsky #histology #pathology #hemepath #hemesky #MPN

Intestinal T/NK lymphoma! Can be very aggressive or very indolent! Aggressive: EATL = Refractory celiac MEITL = Like EATL, no celiac Indolent: IT-LPD = CD4,CD8 types JAK-STAT Slight risk transformation NK-enteropathy = CD56+ JAK3 #MedSky #hemesky #pathsky #hemepath [Jaffe. Haematol.20]

My 1st #pathsky post! Photogenic flame cells in a myeloma aspirate 😍 #hematopathology #hemepath #pathology

Announcement: I will be doing a 2 part pediatric lymph node workshop in January. Targeted to residents, #pedipath/#hemepath fellows and anyone seeing nodes as part of their service. Lots of great cases and WSI! Discounts available for trainees! education.spponline.org/content/2025...

DDX of superficial pediatric small round blue cell tumors are sarcomas (Ewing family and fusion-associated); rhabdomyosarcoma; lymphomas/leukemias; neuroblastoma #dermpath #surgpath #blueskypath #blueskydermpath #blueskysurgpath #hemepath #blueskyhemepath #pathology #blueskypathology

To wrap up the year 2024… We contributed some knowledge to “Cytopathology Practice in Nigeria” The early view can be assessed here: onlinelibrary.wiley.com/doi/10.1002/... #Cytopathology #Cytopath #Pathology

The pathological hallmark of #AllergicContactDermatitis #LangerhanCell microaggregates in the epidermis #pathology #dermatology #pathsky 😁

#Pathology - cardiac angiosarcoma w/ right atrial mass & localized mets in epicardium 🫀 #cardiosky #medsky @ericatirr.bsky.social @drmonikaradike.bsky.social @danielvargasmd.bsky.social @minipakkal.bsky.social @katehanneman.bsky.social

Snow in Boston! Sharing a crazy "snowflake-like" mitosis in this megakaryocyte. Looking forward to being more active on this platform in the new year! #pathology #hemepath

A 37 year-old male with soft tissue mass at L4 with bone destruction CD45+, CD30+ scatter, CD3 small+, CD20-,MPO- Which IHC I should perform for further investiagation? #hemepath #pathology #hematology #pathsky #histology

▶️ Xanthelasma of eyelid Lipid laden foamy histiocytes in superficial dermis, clustering around blood vessel walls #dermpah #pathsky #pathology #histology

No one does a peroidic acid-Schiff stain (PAS) quite as pretty as the UGA veterinary histology lab. Beautiful stain of Aspergillus sp. in the lung of an ivory-billed gull. #fungi #mycoses #vetpath #pathsky #pneumonia

🩸🩺 Feel free to check out these active accounts for all things hematology and internal medicine. #hemesky #medsky #IMsky #internalmedicine #hemeonc #oncsky #hemepath

Cutaneous mixed tumor / chondroid syringoma ▶️ Well circumscribed but unencapsulated -chondroid or myxoid stroma -benign bland epithelial and myoepithelial cells that form glands, ducts, cysts, reticular lace-like networks, nests Ref. Pathology outlines #pathsky #pathology #dermpath #histology

Thyroid gland : invasion #pathology #histology #pathsky #Endopath #thyroid

Abundant H.pylori in the stomach #pathsky #skypath #GIpath #pathology #histology #Helicobactorpylori

#pathsky “When you wonder what a reniform nucleus is, and she looks at you in disbelief.” #dermpath #pathology #dermatology

🩸 Hairy cell leukemia! - Indolent neoplasm of mature B cells—appear w/ cytoplasmic hair-like projections. - PB cytopenias - Splenomegaly - Immunohistophenotyping: CD11c, CD19, CD20 bright, CD22 bright, CD25, CD103, CD123 and CD305 (LAIR) - BRAF V600E > 95% of cases #hemesky #pathsky #hemepath

Central Zone glands #prostate #gupath #PathSky 🌉complex architecture 🌉stratified eosinophilic cytoplasm 🌉prominent basal cell layer 🌉intra-luminal bridges ("Roman arches") 🌉mimic high grade PIN 🌉Rule of👍🏻: in NB from mid gland-base, have higher threshold for diagnosing HGPIN & r/o normal anatomy!

3 month old baby. What is your diagnosis? #pathsky #pathology #heme #medsky

Mucinous fibroplasia in #prostatecancer - amorphous eosinophilic material - represents organization of extravasated mucin - can distort discrete glands leading to over-grading - IMO, in these images, all of the cancer is pattern 3 #gupath #PathSky

#pathsky weak BRAF v600E IHC in bone marrow: Erdheim-Chester's disease in a case with retroperitoneal fibrosis. 1/2