A beautiful example of the sine qua non for diagnosis of central centrifugal scarring #alopecia. Premature desquamation of the inner root sheath (in the s/c fat here). Rupture too. May be focal so keep those 👀 open😉 #pathology #dermatology 💙

Natures master architect at work this morning 💙

Glorious morning at JPUH 😉 OSCE season in full swing. 😅

Summer has certainly arrived 🧡

My name is Jay 💙 #nature

Sunday alarm clock!😉

Beautiful colours 💜

A beautiful Sunday rose ❤️

How to diagnose #ScarringAlopecia #pathology #dermatology Happy Sunday! 😉

#FrontalFibrosingAlopecia 📸1 Normal isthmus. Stem cell location. If destroyed = permanent alopecia. 👀4 arrector pili + seb glands. 📸2 Damaged isthmus. 👀4 muscle. No seb glands. Concentric fibrosis & lymphocytes outside. #dermatology #pathology 💙

My name is Rose 🌹

I love teaching 💚 #MedEd #Pathology

So cute 😉

Ready for takeoff! 😅

My soprano garden singer this evening! 💚

#UsualEpithelialHyperplasia doesn’t get more florid than this. #Cytokeratin5 positive. #ER variable. Note that the apocrine cells next door are CK5 and ER negative. #BreastPath #pathology #BlueskyPath 😉

Lassoed! #BCC encircling a nerve. #PerineuralInvasion #pathology #pathsky 😉

#SolarLentigo 🔬Bulbous elongation of hyperpigmented rete ridges 🔬Increase in basal melanocytes 🔬In contrast to #LentigoMaligna no crowding of melanocytes and no 'clonal' atypia. Occasional mildly atypical cells OK 🔬Sun damaged collagen/elastin 😉💜 #Pathology #Blueskypath

May has arrived and that means I can view another beautiful example of #histology art from @lamellipodium on #Twitter. Always brings ☀️ to my office 💜 #pathology #bluepath

Beware of mucin lobules associated with vessels in a breast biopsy 📸 1. A key feature of mucinous carcinoma 📸 2. Seen on FNA's but easily missed on biopsies if no epithelial islands seen. #pathology #BreastPath #BluePath 😉

The great deceptor at work again! #ColumnarCellChange colonised by #InsituLobularNeoplasia. Top tip! Always look carefully at busy columnar lined ducts. 😉 #pathology #BreastPath #BluePath

#MycosisFungoides #CTCL Atypical intraepidermal lymphocytes tagging along the basal epidermis with halos. No spongiosis. This case really doesn’t need immunohistochemisry to confirm #classic 😉 #pathology #dermpath #bluepath

Requiescat in pace 🕊️ #diabetes

A beautiful example of #RadialScar. The clue to this diagnosis is to identify the characteristic elastotic stroma (distinct from a fibroblastic tubular carcinoma stroma) & then hunt for #myoepithelial cells at high 🔍 #pathology #blueskypath #bluepath 😉💚

The discohesive metastatic menace 😈 #LobularCarcinoma 📸 1 Endometrial invasion 📸 2 Bone marrow invasion (paratrabecular) #pathology #breastpath #blueskypath #pathsky

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Meet some lovely friends/colleagues/star students 4om #NorwichMedicalSchool @uniofeastanglia #pathology #MedTwitter #MedEd 💚❤️💙💜

Happy St.Patricks Day to y’all! ☘️💚☘️💚 Not exactly #pathology or #pathsky 😉

On the lymphatic highway en route to the axilla. #BadNews #BreastCarcinoma #TumourEmboli Hope everyone has a good weekend 💚 #pathology #BluePath #BreastPath 😉

Not commonly seen without a clinical mass! #PagetsDisease of nipple with associated invasion. Also #HGDCIS in subareolar ducts. Usually #ERNegative & #Her2Positive. #pathsky #Pathology #BreastPath 😉

Top tip! Try to scan the sub capsular sinus of sentinel nodes with your 10x objective to spot single lobular carcinoma intruders. 🟣 = lobular carcinoma 🟢 = macrophage 🫛 Cytokeratin to confirm #pathology #BreastPath #PathSky 😉

From my garden today. My name is Iris. Happy Saturday everyone 💜

The 🔑 to diagnose #GlutenSensitiveEnteropathy aka #CoeliacDisease Increased intraepithelial lymphocytes Two images to compare - 1 normal & 1 with #CoeliacDisease 😉 #PathSky #Pathology

GI moonlighting again! #CollagenousColitis Collagen deposition beneath luminal epithelium, entrapping capillaries & inflammatory cells, with an irregular interface with the subjacent inflamed lamina propria. #pathology #GIPathology #PathSky 😉

Gotta 💚 teaching #pathology 😉

The post-capillary venules are in the pathological firing line again this evening. Yikes! This one shows florid fibrinoid necrosis while a helpless arteriole looks on.😢 #LeukocytoclasticVasculitis #pathology #dermatology #PathSky

Happy Valentine’s Day ❤️ Lymphocyte clusters at the tips of flattening villi in the duodenum. #CoeliacDisease #GIPathology #pathology #BluePath 😉

A nice example of #BullousPemphigoid with linear deposition of C3 on #IMF #pathology #dermatology #PathSky 😉

Moonlighting doing some GI tract reporting today. A beautiful series of mucosal granulomas in the colon. #CrohnsDisease #pathology #GIPathology #PathSky 😉

One of the nastiest skin tumours. This one in a vessel enroute to destroy the respiratory membrane diffusion gradient. #MerkelCellCarcinoma #pathology #dermatology #PathSky 👿

A textbook example of #Psoriasis #pathology #dermatology #SkyPath #BlueskyPath 😉

The hallmark of IgA vasculitis! #IMF Granular deposits of IgA in superficial dermal vessels. #dermatology #pathology #PathSky

A nice example of #CutaneousAmyloidosis which read the 📖. Amorphous deposits of eosinophilic, congo 🔴 + material in dermis & vessels, showing 🍏 green birefringence under polarised 💡. #pathology #dermatology #PathSky 😉

Are you a pathology resident preparing for exams or a pathologist looking for some CME? There's still time to register for CAP-ACP's (virtual) Resident Review Course! Recorded sessions available for 4 weeks after. I present a session on need-to-know liver path! cap-acp.org/page/Residen... #pathsky

My first shot of the moon through my telescope with m’iPhone b4 I get a better camera for #astrophotography 😉👽💚

One for the New Year! A nice example of lamellar fibrosis which is the papillary dermal hallmark of a dysplastic naevus - this one shows high grade dysplasia. Hope y’all are having a good 2025 so far! 😉💚 #PathSky

Happy New Year to everyone! 🩵💚🧡❤️😉

Key #pathology skills. #Dissection and #Embedding. #blueskypath 😂🎄🥳🎉

For 2025, moving from microscopy to astronomy. Going to try my ✋ at some #astrophotography 😉 #pathsky 🛸👽

Writing #Christmas cards today. This one shows my #pathological Christmas tree 😉. Hope you like it. #pathsky 🎄