Immunohistochemistry New Instrument Validations: Why Your Validation Plan Matters journals.lww.com/appliedimmun...

🆕 New publication alert 🚨 PC-RPLND from patients with TGCTs: key morphologic variants, diagnostic pitfalls, and clinical impact—read & share! 🔗 www.sciencedirect.com/science/arti... #pathtwitter #pathX #gupath #TGCT #IUPathology #indianapath @iupathology

Exciting news! 🎉 Fiona Maclean joins us as the International Councillor for Australia. Welcome, Fiona — we’re delighted to have your experience and leadership representing Australia and supporting our members across the region! 🇦🇺

Which matters more: talent or luck? In games like poker, luck is clear. In life, it shows up as unexpected chances or being in the right place at the right time. #readinglist #goodread 🔗 www.worldscientific.com/doi/10.1142/...

Investigating Biomarkers in Primary Tumors and Lymph Node Metastases in Tongue Squamous Cell Carcinoma: An Immunohistochemical Perspective journals.lww.com/appliedimmun...

Distinct levels of DDIT3 Amplification in Dedifferentiated Liposarcoma Developing After DDIT3 Rearrangement in Myxoid Liposarcoma journals.lww.com/appliedimmun...

STAT6 Can Be Used in the Diagnosis of Hodgkin Lymphoma; There Are Differences in Expression Among Subtypes journals.lww.com/appliedimmun...

Immunohistochemical Study on Programmed Death Ligand 1 (PD-L1) in Breast Carcinoma and Its Correlation With the Clinicopathological Parameters journals.lww.com/appliedimmun...

🚀 Join us for the launch of our Journal Club Webinar Series! 📚 Articles #openaccess starting July 28 👨🏻‍💻 Don't miss this opportunity to explore new research with us! #AIMMjc Register 👉🏻 tinyurl.com/ycxeye84 🔗 journals.lww.com/appliedimmun... 🔗 journals.lww.com/appliedimmun...

EWSR1::NFATC2 Rearranged Sarcoma Distinct Clinicopathological Features From a Series of 5 Rare Cases journals.lww.com/appliedimmun...

Join us for the 3rd Annual Euro Grawitz Dinner in Vienna! 📅 Sept 10, 2025 | 5:30 PM 🍽️ Zum weißen Rauchfangkehrer Reserve by Sept 3: www.eventbrite.com/e/1527667858... Special thanks to our local organizers making this event possible: Prof. Eva Compérat and Miss Amy Rattan

Colleagues: the ISUP @intsocuropath.bsky.social website has been down recently while a new website was being built. New website is now available isupweb.net and in progress being expanded with additional features! An email to members was sent July 18 via mailchimp.

📚 #readinglist #mustreads Perfect for those starting their careers, Fragale strikes a balance between smart and approachability. Her advice offers actionable tips that help leverage strengths to own your space. @alisonfragale 📖 Have you read it? If not, add it to your list!!

#slidearchiveseries urothelial carcinoma in situ colonizing prostatic urethra #gupath

Check out our Current Issue!! Figure from "Telomerase Immunocytochemistry in Lymphocytes From Chronic Lymphocytic Leukemia” by Sučić, et al. 🔗 Read the full article here: journals.lww.com/appliedimmun...

#slidearchiveseries seminal vesicle invasion #gupath #prostatecancer 1️⃣ spreading along the ejaculatory duct 2️⃣ direct invasion at the base of the prostate or extension into peri-SV soft tissue and then into the wall of the SV 3️⃣ discontinuous metastases (rare) 🔗 doi.org/10.1038/modp...

#slidearchiveseries history of nephrectomy for renal cell carcinoma, received immunotherapy with complete response, later developed upper GI bleeding from metastases to the proximal jejunum #gupath #gipath

The Expression and Clinical Features of 8 Immunohistochemistry Markers in Adrenal Cortical Adenomas and Pheochromocytomas journals.lww.com/appliedimmun...

Just published! Check out this latest article by @iamshreeya.bsky.social 🔬 Molecular subtyping of bladder cancer is essential—but not always feasible in low-resource settings 🧪 IHC markers GATA3, KRT20, KRT14, KRT5 used to stratify UCs ⚠️ Dual-negative had poorest survival (25%), luminal best (80%)

Can you spot treatment effects in prostate cancer and distinguish secondary tumors involving the prostate? This case-based CME session covers ADT/radiation changes, rare variants, and more. Check out this session—plan on joining us at #CAP25! 🔗 events.cap.org/event/cap25/...

#macrovsmicro total nephrectomy, tan to red, nodular, heterogeneous, well-delineated, focally hemorrhagic/necrotic mass #gupath #pathsky #pathoutpic #kidneytumor

Our pathology team is walking to fight kidney disease and support the life-changing work of the @nkf-professionals.bsky.social! On June 21, we walk for all who’ve been impacted by this chronic illness. Join us or donate to help make a difference: www.kidneywalk.org/indy/IUPatho... #kidneywalk

Liver immunostaining for this #FluorescenceFriday

Just published! Check out this latest article 👉🏻 HER2 amplification is rare (1.7%) in low-grade, tubule-forming breast cancers with 2+ HER2 IHC; findings suggest ISH may be unnecessary in this subset #breastpath #IHCpath #pathsky

Expression of Hippo Pathway Molecules in Distal Bile Duct Cancer journals.lww.com/appliedimmun...

Just published! Check out this latest article! 🔵 PD-L1 expression showed high concordance between cores and full slides. 🔵 CD8+ T cell and CD68+ macrophage densities varied; cores underrepresented immune infiltrates. @fabiotavora.bsky.social #IHCpath #lungcancer

Evaluation of Diagnostic Accuracy of Immunohistochemical Markers of SATB2 and Villin in Differential Diagnosis of Ovarian and Gastrointestinal Mucinous Carcinoma journals.lww.com/appliedimmun...

The Value of Routine Reflex In Situ Hybridization Testing in Low-grade Tubule-forming Invasive Breast Cancers With Equivocal HER2 Immunohistochemistry - A Reappraisal of the ASCO/CAP Guidelines journals.lww.com/appliedimmun...

CD140b (PDGFRB) Expression in Atypical Fibroxanthoma/Pleomorphic Dermal Sarcoma and its Cutaneous Neoplastic Mimics journals.lww.com/appliedimmun...

Our pathology team is walking to fight kidney disease and support the life-changing work of the @nkf-professionals.bsky.social! On June 21, we walk for all who’ve been impacted by this chronic illness. Join us or donate to help make a difference: www.kidneywalk.org/indy/IUPatho... #kidneywalk

#slidearchiveseries clear cell renal cell carcinoma with rhabdoid differentiation #gupath 🔬 large eccentric nuclei with prominent nucleoli, abundant eosinophilic cytoplasm, globular eosinophilic intracytoplasmic inclusions

For some people work is just a job. You do it, you leave it, you live your life. For other people work is craft and mastery—it’s a large part of your identity and a big source of fulfillment Both are totally fine.

Laboratory Investigation seeks a Social Media Editor. Are you an MD or PhD with expertise in basic, translational, or anatomic pathology who has experience creating social media posts? @rovingatuscap.bsky.social @uscap.org @anirbanmaitra.bsky.social @katcollmd.bsky.social Link in Comments

Honored to host Dr. Mukhopadhyay @smlungpathguy.bsky.social at this week's Grand Rounds. Grateful for the opportunity to learn from one of the best—his depth of knowledge and gift for teaching truly shine through #lungpath

#PathSky 45 with a forearm skin tumor. Highly cellular, monomorphic spindle cell tumor with a “packeted” pattern and deep, nodular lymphoid aggregates.

#publicationalert 🚨 α-SMA loss in the inner circular layer of jejunal muscle was common in both motility disorder cases and controls, making it an unreliable marker of dysfunction #gipath #pathsky 🔗 pubmed.ncbi.nlm.nih.gov/40328644/

#openaccess for 50 days to our article! Click on this link before June 17, 2025 to read and/or download! #gupath 👉🏻 authors.elsevier.com/c/1k-wWKZx3jmow

Follow us to stay connected and up to date! #pathsky @katcollmd.bsky.social Where to find us: ➡️ Website: journals.lww.com/appliedimmun... ➡️ Twitter: x.com/aimmjournal  ➡️ Instagram: instagram.com/aimmjournal ➡️ Bluesky: bsky.app/profile/aimm...

Thrilled to share USCAP’s U²P² program — supporting pathologists from under-resourced countries to train at leading institutions! Fully funded by the @uscap.org, it’s a bold step toward global collaboration and education in pathology! #pathtwitter #U2P2 🔗 foundation.uscap.org/u2p2/

#PathSky 55F, large retroperitoneal mass. Outside pathologist quite reasonably thought of WDL, but MDM2 FISH was negative. Any other ideas?

🌟POSITION OPEN: #ISUP International Councillor Europe 🌟 📅 Submit by April 27, 2025 We invite interested members to apply for this role. Please submit your CV and a personal statement to [email protected].

#publicationalert 🚨 Isolated nodal disease post-NAC linked to higher recurrence, not worse survival after cystectomy #gupath 🔗 pubmed.ncbi.nlm.nih.gov/40250715/

#publicationalert Rare case of EBV+ classic Hodgkin lymphoma in Crohn disease highlights a potential link to anti-TNF-α therapy #gipath #IBD #hemepath #pathsky 🔗 dx.doi.org/10.1002/jgh3...

New platform, same mission. The CAP is now on Bluesky—join us as we share updates that matter to pathologists and the future of medicine. #pathology #Pathsky

Any other #gupath tweeps ? how to incorporate tertiary Gleason Patterns into Grade Groups? e.g., 4+3=7 w/tertiary 5 might belong in GG 4, based on language from original pubs (but not WHO book) & fig from@GladellPaner @rovingatuscap @Williamson_SR ncbi.nlm.nih.gov/pubmed/26542947

#slidearchiveseries urinary bladder, inflammatory myofibroblastic tumor #gupath #pathsky #pathoutpic 🔬 Diverse patterns: myxoid, fascicular, hyalinized 🎨 ALK IHC (diffuse cytoplasmic) in 40-60% 🧬 50-60% ALK fusions (EML4, TPM3/4, CARS, RANBP2, IGFBP5…)

#slidearchiveseries urothelial carcinoma, clear cell (glycogen-rich) #gupath 🎨 IHC profile similar to conventional urothelial carcinoma (GATA3, p63) ⚠️ distinguish from metastatic CCRCC and clear cell adenocarcinoma

#PathSky Abdominal wall mall mass, 65M. Multinodular with thick fibrous septa. Bland spindled to ovoid cells surrounding prominent vessels. Microcystic, pseudoglandular spaces.