A recent RCT published in @jamanetworkopen.com finds #pharmacist-led outreach guided by an evidence-based hypoglycemia-prevention algorithm was more likely to lead to safer diabetes prescribing compared to a control group. Read the full study here: buff.ly/0uBaX11

The OPERAM Trial was a multi-country RCT investigating the effects of hospital pharmacotherapy optimization on drug-related hospital admissions in multimorbid, older adults with polypharmacy. A longitudinal secondary analysis of the trial revealed many interesting findings: buff.ly/9hehjjb

It was a great talk indeed! Thanks for having us, @nhp-uoft.bsky.social Learn more about our DIAL study here: lnkd.in/gxncjf2a Our antihyperglycemic #deprescribing tools can be found here: lnkd.in/ggwJhCCy

A review of 31 medico-legal cases involving #deprescribing across Canada 🇨🇦 highlights that we still have much to learn on how to improve deprescribing practices in primary care in older adults: link.springer.com/article/10.1... @cmpa-acpm.ca @springernature.com

Could Artificial Intelligence (AI) help or harm efforts to reduce low-value tests and treatments? 📅 Join @choosingwiselyca.bsky.social on Feb 12, 2026 at 12:00 pm ET to learn more about the role of AI in addressing overuse in healthcare. 👇 Register here: buff.ly/EGfXzmx

Check out a Virtual Seminar on "Resetting the DIAL on diabetes management in long-term care homes" on Tuesday, February 17 from 12:00 to 1:00 p.m. ET with @lisamccarthy.bsky.social & @ilianalega.bsky.social ⛓️‍💥 Register here: buff.ly/bP3POSt

A Clinical Trial published in @jama.com finds Electronic Health Record (EHR) prompts informed by behavioural-science can significantly increase the rates of #deprescribing of potentially inappropriate medications used by older adults: buff.ly/uF489QP

Great editorial in @bmj.com written by our deprescribing.org Co-Director Wade Thompson, along with Anton Pottegård! buff.ly/DfygbLS While PPI use without an indication is a recognized problem, we should also avoid using low-quality evidence to justify #deprescribing decisions.

January is Alzheimer's Awareness Month in Canada! By 2030, researchers project that nearly 1 million people in Canada could be living with dementia. No one should face dementia alone. Learn more about dementia and how you can help at: alzheimer.ca/en #ForgetNoOne

New research letter published in @jama.com showed an encouraging decline in potentially inappropriate CNS-active prescriptions from 2013 to 2021 in United States Medicare data. 📉 buff.ly/OgmSJbr However, more work still needs to be done to further reduce the use of CNS-active PIMs.

Register to the next Int'l Deprescribing Journal Club on Feb 26! Hosted by the Portuguese Deprescribing Network, Dr. Teixeira Rodrigues presents the design & implementation of C-SENIoR, an interprofessional (GP & pharm) deprescribing model to optimise PPI use in older adults. tinyurl.com/bdhh5kpp

Recent survey study from @journalgim.bsky.social finds low concordance between patients & their GPs with regard to identifying PIMs for #deprescribing. Explicit discussions considering both patient & GP perspectives are needed for deprescribing success! Read the full article here: buff.ly/deJXgyT

🔍 Check out the latest addition to our Deprescribing Guidelines Repository (DEPOT)! "The Joint Clinical Practice Guideline on Benzodiazepine Tapering" from the American Society of Addiction Medicine provides comprehensive benzodiazepine tapering guidance. Read more here: buff.ly/TJOQUBw

🌍 Antihypertensives are among the commonly prescribed medications globally. Read about a recently-published systematic review & meta-analysis on #deprescribing antihypertensive medications in older people, conducted together with our collaborators here: buff.ly/CPznF05

Read about the thoughts of key global deprescribing stakeholders from the 2024 Australian Deprescribing Network Meeting regarding: 💡 The current landscape of #deprescribing research and practice ‼️ The top future priorities for deprescribing 👉 buff.ly/8e2MMZp @deprescribeau.bsky.social

Merry Christmas and Happy Holidays to all from deprescribing.org! ✨ Wishing everyone a safe and joyous holiday season! ❤️ May your holidays be focused on what truly matters - sometimes "less is more" both with prescriptions and with life!

Longitudinal cohort study of over 30,000 participants from U.S. National Survey data finds a strong association between PPI users with reduced kidney function and death from any cause. 🚨 Caution is needed when considering PPI use for CKD patients! Read the full article here: buff.ly/kTz5275

As part of the PIP-STOPP study, read about an innovative approach to improve the applicability of the STOPP-START and Beers Criteria for identifying potentially inappropriate medications at a population-level using diagnostic & medication codes! Find the open-access article here: buff.ly/QZSFFfh

Check out ISMP Canada's December 2025 Bulletin describing the collaboration between @deprescribing.bsky.social and Canada's Drug Agency in the development of new tools for patients, care partners, and health providers to combat inappropriate #polypharmacy! ismpcanada.ca/bulletin/pol...

Congratulations to Armin Farahvash & his team for winning the Dr. John Dupré Award, recognizing the highest ranked resident research poster at the 2025 Diabetes Canada / CSEM Professional Conference!

Cohort study published in @jamanetworkopen.com investigated 120 older US veterans who potentially experienced a Gabapentinoid-Loop Diuretic prescribing cascade. Important findings including the downstream harms of this prescribing cascade can be found in the full article here: buff.ly/R41BH0Q

💡 Large retrospective study finds approximately 1 in 20 nursing home residents who start #gabapentinoids go on to receive a loop diuretic within 3 months. The study highlights the prevalence of an often overlooked prescribing cascade! Read the full article here: buff.ly/5u5O3qh

Patient's attitudes towards their medications, information-seeking behaviours, & #deprescribing preferences were studied across 14 different countries 🌍 , with 3 distinct categories of patients found. Discover detailed insights from the full study here: buff.ly/lbGyF2c

Great to see our Co-Director Wade Thompson's contribution to a reflective article on Supporting Medication Appropriateness Among Indigenous Peoples in Canada! Read about the CADeN Indigenization Working Group (IWG) and their learnings in the full article here: buff.ly/RebVOAX

A Budget Impact Analysis conducted for adult patients using PPIs long-term inappropriately in England, UK 🇬🇧 found an estimated net savings of £11.5 million would be realized over a 5-year period if 20% of patients had their PPI stopped! Read the full analysis here: buff.ly/LaRmDOK @england.nhs.uk

Check out @wypartnership.bsky.social and @england.nhs.uk's new webpage on "Anticholinergic Medicines" and their risks below 👇 www.wypartnership.co.uk/our-prioriti... Always great to see new resources promoting safe medication use in older adults!

🎉 Our Fall 2025 Newsletter is now out! 🎉 Learn all about our updates, including new resources, publications, & more: buff.ly/Pi2BUmf A heartfelt thanks to all of our team members, partners, & collaborators that helped to spread the word of #deprescribing over the past year! 👏

The C-SENIoR Trial, recently published in the Drugs & Aging journal by @springernature.com demonstrates the outcomes of a multifaceted, multidisciplinary intervention on Proton Pump Inhibitor (PPI) #deprescribing! Read the full article here: link.springer.com/article/10.1...

Great to see Opioid Deprescribing highlighted in @nejm.org! Opioid deprescribing through a tailored, patient-centered plan is recommended when the potential harms of opioid therapy outweigh the potential benefits. Link to the article here: nej.md/4oL3fu2 @sydney.edu.au

🚨 Be sure to sign-up for the "More Medications May Not Be Better" Webinar hosted by the Canadian Medication Safety Network on Wednesday November 26 from 12 - 1 PM ET! Join the conversation on addressing potentially inappropriate #polypharmacy. Registration Link: us02web.zoom.us/meeting/regi...

Join @choosingwiselyca.bsky.social on November 18 at 1 p.m. ET for a free online webinar on "How Urine Tests Drive Antibiotic Overuse Across Health Care Sectors"! Learn about how low-value urine testing can lead to unnecessary testing and antibiotic use. Registration link here: buff.ly/gHM3DqB

deprescribing.org, Canada's Drug Agency, & ISMP Canada, are happy to have co-developed '5 Tips to Manage Polypharmacy', a new resource for clinicians to emphasize 5 crucial tips to manage #polypharmacy. ➡️ Find Links to the Full Toolkit and Shareable Handout here: deprescribing.org/resources/5-...

Intriguing study from @thelancet.com finds #deprescribing sleep medications in adults over age 50 could: 📉 Reduce the lifetime incidence of falls by 8.5% & cognitive impairment by 2.1% 📈 Increase life expectancy by 0.11 years 💵 Result in net lifetime savings of $6,600 per person buff.ly/515uJ9s

Don't miss out on a free webinar, "Taking multiple medications? 5 questions to ask" to be presented by @dremilymcd.bsky.social on Oct 29, 2025 at 12:00 PM ET hosted by the Canadian Medication Appropriateness and Deprescribing Network! 👉 Find the registration link here: buff.ly/3aF4mbB

🎉 Congrats to Sameera Toenjes and her team for an excellent publication in @plosone.org highlighting the perspectives of primary care clinicians regarding perceived barriers, facilitators, and team roles in addressing prescribing cascades: Read the full article here! buff.ly/yscPvts

Thanks @daphneberryhill.bsky.social for showcasing deprescribing.org on the "Meet Me at the Medcart" substack! Read the full article where Daphne and @lisamccarthy.bsky.social discuss key points to keep in mind while #deprescribing: buff.ly/gLm4BgI Consider following the Medcart Substack! 👏 👏

Great article from Sarah Fallis, Ivy Lam, @lisamccarthy.bsky.social, & Myles Sergeant sharing how optimizing medications in hospitals can: ✅ Improve Patient Outcomes ✅ Reduce Medication Costs ✅ Lessen Environmental Impact ✅ Optimize Staff Efficiency ftp.longwoods.com/content/2767...

Check out Canada's Drug Agency's new pan-Canadian Appropriate Use Strategy! 🇨🇦 www.canada.ca/en/health-ca... deprescribing.org is so happy to have contributed to this important work to build a collaborative, coordinated, pan-Canadian approach to the appropriate use of prescription medications!

🌍 A large study spanning 14 countries found older adults with lower socioeconomic status had: ➡️ A greater interest in #deprescribing ➡️ Lower satisfaction with their current medications, self-rated health, & health literacy Find the open-access full article here for more insights: buff.ly/k0C5Em3

🚨 Last call to submit your abstracts to the International Conference on Deprescribing (ICOD) happening in Montréal Canada from April 27-29, 2026!! The submission deadline is on October 15, 2025 at 11:59 PM Eastern Daylight Time. Don't miss out on a chance to share your #deprescribing research!

Ever seen #deprescribing captured beautifully in a song? 🎶 Thank you Bob Heath and Peter for their incredibly creative performance inspired by the experiences of people with dementia and their carers. Watch the full performance of "Medication Review (She's Listening) here: buff.ly/JDz9MFh

Sharing a powerful video from Dr. Kinda Ibrahim's team highlighting: 💡 The often-overlooked burden of overmedication for both people living with dementia as well as their carers. 💡 The importance of regular medication reviews to ensure each medication is doing more good than harm.

Scoping review in @agsjournal.bsky.social finds few studies explicitly incorporate or measure Shared Decision Making (SDM) in deprescribing interventions for older adults: buff.ly/WF5FzSb More evidence linking SDM in deprescribing interventions with health and behavioural outcomes is needed!

📢 The International Conference on Deprescribing (ICOD) 2026 in Montréal Canada is now welcoming abstracts submissions until October 15, 2025 (11:59 PM Eastern Daylight Time)! Access the abstract submission platform here: events.decorporate.ca/ICOD2026/abs... We hope to see you there!

September 25 is World Pharmacists Day! Every day, #pharmacists across the globe help to ensure the appropriate use of medications and improve health outcomes. 🌎 Happy Pharmacists Day - from our deprescribing.org pharmacists, to our pharmacist colleagues worldwide! #ThinkHealth #ThinkPharmacist

Looking for a new podcast for your commute? 🎧 Check out the latest @prescqipp.info info #TalkingMeds podcast where our @deprescribing.bsky.social Co-Director @lisamccarthy.bsky.social and host @jonathanunderhill.pharmsky.app discuss person-centered deprescribing, ICOD 2026, and more!

September 17 is World Patient Safety Day! Organized by the World Health Organization, this year's theme is, "Safe care for every newborn and every child", with the slogan, "Patient safety from the start!" 🧸 Read more about this year's campaign here: buff.ly/RjHaMcL

So happy to have contributed to ISMP Canada and Canada's Drug Agency's new "5 Questions to Ask About my Multiple Medications" resource for patients and caregivers! Find the helpful handout and toolkit here: www.cda-amc.ca/appropriate-... Please spread the word!! 🎉

Scoping review maps out the most commonly used tools for identifying PIMs, including which tools are most suitable for research using registry data: buff.ly/hbCcC63 Highlighted tools useful for register-based research include: ➡️ The EU(7)PIM List ➡️ PRICUS List ➡️ Zhan Criteria ➡️ NORGEP

People with Dementia (PWD) are frequently exposed to #polypharmacy and potentially inappropriate medication use. Check out this useful article from Dr. Ariel Green's team at John Hopkins University providing a structured roadmap on #Deprescribing for People with Dementia! buff.ly/Nlo5vZI