New paper from my 2nd PostDoc is now published in The ISME Journal by @isme-microbes.bsky.social! #Sulfur disproportionation occurs globally across anoxic habitats & has multiple mechanisms of independent evolutionary origin academic.oup.com/ismej/advanc... #Bacteria #Microbes #Evolution #DeepSea

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating). A brief 🧵 (carried over from the old place)

CRISPR spacers reveal diverse and abundant Thermococcales viruses in hydrothermal vents www.researchsquare.com/article/rs-8...

Openness means more than access. That's why we encourage submissions of Replication Studies. Learn about publishing your replication study with us in our author guide: buff.ly/rcI0oAY

One of the biggest questions in biology is how complex cells evolved about 2 billion years ago. Here's my new story on how scientists are solving the mystery of eukaryotes like us. Gift link: nyti.ms/4qMbo22

Nice review by Urmila Chadayammuri of Maria Popova's new book Traversal. I have reviewed it for @science.org (coming soon) and my take has a lot of overlap with Urmila's. In short, it is a strange beast and all the better for that. www.nature.com/articles/d41...

🧬 A major data reanalysis in December's most-read Genetics paper uncovers thousands of previously hidden protein-coding regions in human and mouse genomes: buff.ly/6TsX3ct

Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life url: academic.oup.com/nar/article/...

A web-based atlas for exploring post-transcriptional regulation in the archaeon Sulfolobus acidocaldarius #microbiology #archaea #MicroSky #ArchaeaSky @asm.org journals.asm.org/doi/10.1128/...

How the ocean’s hydrothermal systems made the first life on Earth possible

New preprint from my lab (with Arya Kaul, @fernpizza.bsky.social, and @brinda.eu), in which we explore new genes hitchhiking on the beneficial deletion that fused them together, and find them in the LTEE, M. Tb/bovis, and across the bacterial tree of life

Now published in Nature Biotechnology: go.nature.com/44P7nSm If you missed it, the TL;DR is in my April thread below

A cool genetic system to study site-pecific replication fork collapse and repair from the brilliant @winterhalterlab.bsky.social www.nature.com/articles/s41...

Out today in @cp-cell.bsky.social! We studied how environmental stresses like high-fat diets today can prime tumorigenesis months to years in the future (1/n)

FYI: New online! Detecting transcription factor binding sites with PADIT-seq

1. As we recently joined BlueSky, we want to repost this story for all newcomers! We sat down with @radler92.bsky.social to get more insight into the unique videos from his recent preprint on Promethearchaeota (formerly Asgard archaea). doi.org/10.1101/2025... (Videos and info below)

So you think your mammalian plasmids have nothing to fear from cloning and propagation in E.coli? Quantitative profiling of millions of nucleotides by Tom Copeman will prove you wrong! Supervised with the amazing @proftomellis.bsky.social and AZ, now on BioRxiv: doi.org/10.64898/202...

Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious? Either way, we have good news. We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July. Sign up: meetings.embo.org/event/26-arc... We look forward to seeing you in Cambridge, UK. Please repost!

🚨 What if evolution is the ”law”… and networks are the machines that do the work? In this paper (just published) I try to formalize how living systems are non-equilibrium, information-processing, adaptive matter. With a great biological flavor! 🧪🌐🌍🧬🦠 👉 iopscience.iop.org/article/10.1... 🧵 1/

The scikit-bio paper in online in Nature Methods! Many thanks to our collaborators, community contributors and reviewers! We couldn’t have done it without you. www.nature.com/articles/s41... #Bioinformatics #OpenSource

Now published. Thank you very much to our collaborative team, and very supportive editors and reviewers!!! www.pnas.org/doi/10.1073/...

Our study on ribonucleotides incorporation the genomes of Haloferax volcanii and Thermococcus barophilus is new published in #NAR #ribonucleasesH academic.oup.com/nar/article/...

Nature research paper: Ribonucleotide incorporation into mitochondrial DNA drives inflammation go.nature.com/3KBRg2W

A high-resolution genome mapping technique now enables detailed study of transposons, offering new insights into genetic evolution, disease mechanisms, and potential agricultural advancements. doi.org/hbb5vk

How do cells activate or silence genes? Read about the #LaskerAward winners who devised ingenious experimental methods, leveraged offbeat model organisms, & capitalized on underappreciated observations to understand how organisms carefully control gene activity. #LaskerLaureate 🧪

Academia is plagued by not-fit-for-purpose metrics that are then used ranking individuals and institutions Will we ever move away from these? - there is a lot of talk but not a great deal of action? The comment ⬇️ is a refreshing look at the problem. www.nature.com/articles/d41...

The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology journals.asm.org/doi/10.1128/...

Methanobrevibacter smithii: Trends in Microbiology www.cell.com/trends/micro...

AI is not just another research tool; it is redefining what research is, how it is done and what counts as an original contribution go.nature.com/47Uh6sf

Artificial intelligence has enabled the complete mapping of Phage G, the largest cultivated bacteriophage, providing a new model for studying megaphages and potential antimicrobial applications. doi.org/g98g28

Big pharma seduced by transcription factors again. What has changed? www.nature.com/articles/s41...