The U.S. regulatory path for AMT-130 remains complex, but uniQure has announced plans to seek approval for its Huntington’s disease gene therapy in the UK. Full Article: en.hdbuzz.net/a-second-pat...

Happy Easter from the BBC

My best capture yet of the beguiling whirlpool galaxy. Captured over 4 nights in RGB + hydrogen-alpha from Bethnal Green

Oh

Jupiter from last night 🔭 C11 + AM5R + ASI678

So depressing that the em dash has become synonymous with AI. I used to love using those long boys :—(

HDBuzz was at the HD Therapeutics Conference, and brought you live updates on the latest research in Huntington’s disease. Read up on the exciting science, new discoveries, and insights straight from the researchers working to move the field forward. en.hdbuzz.net/huntingtons-...

The heart and soul nebulae in the constellation of Cassiopeia. Approx 7,500 light years away. Captured from Bethnal Green around new year

Curious when you should expect the next clinical trial update for Huntington's disease? The HDBuzz Trial Tracker puts future updates for HD trials on a clear timeline, along with in-depth explanations in our articles when you want them. en.hdbuzz.net/keeping-up-w...

3I/ATLAS, just the third interstellar object detected from earth. Captured from London , 12 hours after its 5 billion year journey towards us from some remote solar system. Now heading back into the void, and will likely never be seen again by any sentient creature

I am incredibly honoured to share that I have been awarded the @ukdri.ac.uk PhD Prize at #Connectome 2025! @ucl-hd.bsky.social @uclqsion.bsky.social @uclbrainscience.bsky.social

Check out the October 2025 edition of the #HD Clinical Trials Update, now published in the Journal of Huntington's Disease and available online! 🔗 journals.sagepub.com/doi/10.1177/... @profwild.bsky.social @ucl-hd.bsky.social @uclqsion.bsky.social @uclbrainscience.bsky.social

Stephan’s quintet - a group five galaxies ~280million light years away. Captured from Bethnal Green over six nights

The squid nebula - discovered in 2011 by an amateur astronomer. Captured over five nights from London and Italy

Ink poisoning turned out to be much less of an issue than it seemed when I was a kid

The wizard nebula, captured over several nights from London and an eleventh century Italian watchtower

A global clinical trial for a new Huntington’s disease treatment has posted positive results today, announced by trial sponsor uniQure and UCL scientists Prof Sarah Tabrizi and @profwild.bsky.social @uclqsion.bsky.social @uclbrainscience.bsky.social. Watch on BBC News at One 📺

"Congratulations to the global Huntington's disease community. This result belongs to everyone." @profwild.bsky.social #curehd www.youtube.com/watch?v=bhEx...

Good morning everyone! I have a feeling today is going to be a good day 🌅

A highly preliminary Saturn from my new telescope

The Ghost of Cassiopeia captured over 6 nights from Bethnal Green. It’s interstellar matter interacting with the middle star from the constellation’s W #astrophotography #astronomy

Wow the future turned out amazing. You get to go on the computer every day

I fondly remember my previous incarnation as a kingfisher. Halcyon days

My opinion on all competitive sports

Galaxy C30 in September 2024 (top) and last night (bottom). A star exploded 40m years ago and its light reached earth 2 weeks ago as supernova SN2025rbs. Taken by me from Bethnal Green #astrophotography #astronomy

This will be disappointing to many, but it’s the right decision. Regulators consider data. After 6 negative trials it’s time to admit the data don’t support pridopidine as a symptomatic (2006-2015) or disease-modifying (2015-2025) treatment for #HuntingtonsDisease www.dutchnews.nl/businesswire...

New paper from the @hob-lab.bsky.social just published in Journal of Neurology. A step toward more accessible biomarker testing 🩸 link.springer.com/article/10.1... @drl-bo.bsky.social @uclbrainscience.bsky.social @uclqsion.bsky.social

Important paper on accessible biomarkers from @hob-lab.bsky.social. Well done Annabelle Coleman @drl-bo.bsky.social and all.

@goodlawproject.org please could you follow me so I can DM?

Where else are we planning to open HDClarity sites? We are currently in the process of opening recruitment to the study into other countries, including Melbourne, Australia, and Lisbon, Portugal.

How does HDClarity work - and what is a lumbar puncture? 🧵 #Huntingtonsdisease #HDClarity

💬 UCL Huntington’s Disease Centre's @profwild.bsky.social said: “More sensitive tools to measure disease progression are particularly valuable in rare diseases like Huntington’s disease." Access the research here: buff.ly/hCk99kS

A series of digital tests carried out via a smartphone app could enhance the detection of disease progression in #HuntingtonsDisease and improve the efficiency of clinical trials, finds research led by scientists at @uclqsion.bsky.social @ucl-hd.bsky.social and Roche including @profwild.bsky.social

New paper in BRAIN from Team Wild and Roche: A digital motor score for sensitive detection of progression in Huntington’s disease (open access) doi.org/10.1093/brai...

Exciting news regarding new study sites for the HDClarity study 🧵 #HuntingtonsDisease

I can’t believe there are people who allow PowerPoint to choose where the line breaks go in their slide titles

Excitement and Anticipation as PTC’s Huntington’s Disease Drug Clears a Major Hurdle to Sprint Home https://en.hdbuzz.net/433

My thoughts on the @ptcbio.bsky.social Pivot-HD top line results #HuntingtonsDisease #votoplam ir.ptcbio.com/static-files...

Check out the March 2025 edition of the #HD Clinical Trials Update, now available online in the Journal of Huntington's Disease @profwild.bsky.social 🔓 Open access link: journals.sagepub.com/doi/10.1177/... @ucl-hd.bsky.social @uclbrainscience.bsky.social @uclqsion.bsky.social

April 2025: This Month in Huntington’s Disease Research https://en.hdbuzz.net/430

Congratulations to Richard Ayoade for getting the Pope’s funeral English translation gig. An unexpected choice and an invigorating one

@movedisorder.bsky.social I have written a memoir that should be on interest to the MDS members. To be published May 31 by Cambridge University Press and also on Amazon:

Roche provides an update on tominersen: What’s next for this huntingtin-lowering drug? https://en.hdbuzz.net/427

It's Good News Thursday! UniQure has been granted Breakthrough Therapy designation for AMT-130. Development and review will be expedited. Woohoo! It's given to drugs that could treat a serious condition and have prelim clinical support for solid improvement on clinically significant endpoints.