Afaf Osman
@afafosman.bsky.social
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📥 96
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Hematologist-scientist at the University of Utah Huntsman Cancer Institute
Love our brilliant genetic counselors
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4 days ago
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learning about Hepcidin from the legendary Dr. Ganz at our yearly Wintrobe lecture.
2 months ago
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learning about Hepcidin from the legendary Dr. Ganz at our yearly Wintrobe lecture.
2 months ago
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Afaf Osman
Science News
2 months ago
Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans
www.science.org/doi/10.1126/...
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Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans
Obesity-associated saturated long-chain fatty acids regulate lung macrophage phenotype and function at steady state and during lung inflammation.
https://www.science.org/doi/10.1126/scitranslmed.adp5653
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Blood Journals' Portfolio
3 months ago
The revised AML relapse model includes 9 predictors, grouped into 3 risk categories that are each associated with distinct OS.
buff.ly/woUnuRm
#hemesky
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Stephen Leahy
4 months ago
A reminder that tens of millions of people are being exposed to dangerous levels of wildfire smoke again this summer. Wildfire smoke can be up to 10 times more harmful to people than other sources of smog
#wildfire
leahy.substack.com/p/wildfire-s...
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Wildfire Smoke: Unsafe In Any Amount
New research reveals the health risks of breathing wildfire smoke
https://leahy.substack.com/p/wildfire-smoke-unsafe-in-any-amount?utm_source=publication-search
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Perfect day for a baby’s first real hike! Representing team
#myeloid
!!!
4 months ago
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Ming Y Lim, MBBChir
4 months ago
🧠💉 Curious about how aging affects your blood? Join Dr. Anna Parks for a fascinating talk on aging and blood clots—what you need to know, what science is discovering, and how it could impact your health.
hemostasistoday.com/insight/nbca...
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NBCA Hosts PEP Talk with Dr. Parks on Aging and Blood Clots - Hemostasis Today
NBCA Hosts PEP Talk with Dr. Parks on Aging and Blood Clots / Aging, Anna Parks, Beeson Award, Blood Clots, Hemostasis Today, National Blood Clot Alliance,
https://hemostasistoday.com/insight/nbca-3450
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Afaf Osman
The Salt Lake Tribune
4 months ago
The "iconic and magical" cottonwood trees are the keystone species of the plant world and they're disappearing from Utah riverbanks. Scientists are trying to protect thembut budget freezes by President Trump jeopardizes the work.
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Cottonwoods used to line the Colorado River in Utah. What’ll bring the trees back?
The "iconic and magical" cottonwood trees are the keystone species of the plant world and they're disappearing from Utah riverbanks. Scientists are trying to protect thembut budget freezes by President Trump jeopardizes the work.
https://www.sltrib.com/news/environment/2025/07/19/why-cottonwood-trees-are/?utm_campaign=snd-autopilot
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At some point, someone invested in us. Now it’s our turn. Join me in supporting the
#Fight4Hematology
and help secure the future of hematology research and care! Support the @ASH_hematology foundation
hematology.org/foundation
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ASH Foundation
The ASH Foundation is dedicated to moving hematology forward through charitable support for ASH programs – helping hematologists conquer blood diseases worldwide.
https://hematology.org/foundation
4 months ago
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Proud to share our paper describing two large Li Fraumeni cohorts with a wide variety of hematologic malignancies, some with surprisingly good outcomes: Hematologic Malignancy Frequency, Phenotypes, and Outcomes in Li-Fraumeni Syndrome | JCO Precision Oncology
ascopubs.org/doi/full/10....
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ASCO Publications
https://ascopubs.org/doi/full/10.1200/PO-24-00860
5 months ago
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Thinking of the millions who have to withstand this heat with no electricity or air conditioning ..
5 months ago
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Heartbreaking but he did get to meet his daughter RIP
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5 months ago
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Geoffrey Barnes, MD, MSc
5 months ago
Practice-changing RCT at
#ISTH2025
Late-Breaking Clinical Trial!!! In acute VTE patients, apixaban therapy led to less clinically-relevant bleeding than rivaroxaban for the first 3 months of therapy. Kudos to Dr Castellucci and colleagues.
#COBRRA-VTE
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Can’t say I didn’t expect
#VERONA
to be negative but still disappointing. Just had to do a hospice conversation with a patient with high risk
#MDS
. We desperately need new therapies for this disease.
5 months ago
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hope.huntsmancancer.org/sportsfest25...
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Huntsman: 2025 Huntsman SportsFest : Afaf's Against Cancer
I have signed up for the Huntsman SportsFest with the goal of raising funds for Huntsman Cancer Institute.
https://hope.huntsmancancer.org/sportsfest25/afafs-against-cancer
6 months ago
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The BEST way to go back to work after maternity leave: the inaugural Western Blood Conference at the beautiful Sundance
#wbc2025
@ramgar29b.bsky.social
@huntsmancancer.bsky.social
6 months ago
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Proud of this collaboration with my long time mentor and friend.
www.nature.com/articles/s41...
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Predisposition to hematopoietic malignancies by deleterious germline CHEK2 variants - Leukemia
Leukemia - Predisposition to hematopoietic malignancies by deleterious germline CHEK2 variants
https://www.nature.com/articles/s41375-025-02635-1
6 months ago
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Anand Patel
7 months ago
Very excited to share that that the Myelomatch study I am leading is open to accrual! We are investigating ASTX727 +/- enasidenib in higher-risk IDH2m MDS
clinicaltrials.gov/study/NCT065...
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Afaf Osman
Altmetric
8 months ago
Mike spotted this before the rest of us. 🫡 Publications from 2025 are shared more on Bluesky than on X/Twitter.
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I’m not surprised
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9 months ago
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American Association for Cancer Research (AACR)
9 months ago
Research-driven advances in cancer science have led to new treatments for the thousands of people diagnosed with rare cancers. Learn more on
#RareDiseaseDay
:
cancerprogressreport.aacr.org/progress/cpr...
.
#CancerResearchSavesLives®
#FundNIH
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Mark Hartmann
9 months ago
Actually, not so rare at all!
#RareDiseaseDay
Affecting a substantial part of human kind! Support research on rare diseases! Picture from
rarediseaseday.org
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Afaf Osman
Huntsman Cancer Institute
9 months ago
In 2025, about 1 in 5 cancers diagnosed in the U.S. will be considered rare. Though uncommon individually, rare cancers impact over 400,000 people each year. This weekend, the Beacon of Hope shines in zebra stripes to honor Rare Disease Day and those affected by rare cancers.
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Today is
#rare
disease day. Many of the cancers we treat are rare diseases.
#NIH
and
#NCI
funding is critical to support research on rare diseases specifically.
9 months ago
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Afaf Osman
Enigma8750
9 months ago
James Webb Satellite took a fantastic shot of the Planet Saturn with it's Near Infrared Camera (NIRCam) and the Mid-Infrared Instrument (MIRI). This is just an Amazing shot that shows the planet and the rings in brilliant detail.
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Well deserved!!
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9 months ago
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Thank you AACR for advocating for cancer research at such a critical time.
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9 months ago
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Add to that the priceless human impact of our research
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9 months ago
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new morning ritual: check whether the K08 NOFO still exists :D
9 months ago
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John Prensner
9 months ago
This is a beautiful, important new paper that forges a link between mRNA epitranscriptomes, cancer variants, and response to therapy. This should be on everyone's reading list.
#RNAsky
#CANsky
#genomics
#bioinformatics
#GENEsky
🧬 💻 🧪
www.cell.com/cell/fulltex...
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Synonymous mutations promote tumorigenesis by disrupting m6A-dependent mRNA metabolism
The impact of synonymous mutations remains elusive. Here, the authors demonstrate that synonymous mutations can promote tumorigenesis by disrupting post-transcriptional m6A modification. The findings ...
https://www.cell.com/cell/fulltext/S0092-8674(25)00095-9?dgcid=raven_jbs_aip_email
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Afaf Osman
WHO
9 months ago
Today is International Day of Women & Girls in Science. Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬
#WomenInScience
#WomenInSTEM
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to be 9 months pregnant in the middle of this chaos is a test of resiliency haha :D
9 months ago
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Afaf Osman
Kevin M. Kruse
9 months ago
Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic.
globalnews.ca/news/9793403...
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How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
https://globalnews.ca/news/9793403/ozempic-canada-scientist-venomous-lizard-weight-loss/amp/
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Neil Shubin
9 months ago
Gene editing technology began by people studying salt marshes. Ozempic began by folks studying the venom of Gila Monsters. Support for basic science has empowered us to understand our world. Tethering it to applications health has transformed and saved countless lives.
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Neli Ulrich
9 months ago
Gita is such a wonderful colleague and leader at
@huntsmancancer.bsky.social
!
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Afaf Osman
Science Magazine
9 months ago
The Howard Hughes Medical Institute, the nation’s largest private funder of biomedical research, yesterday killed a $60 million program aimed at making universities’ STEM education more inclusive.
scim.ag/3EtS0US
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HHMI kills program aimed at boosting inclusivity in STEM education
“Inclusive excellence” program had committed $60 million to 104 institutions
https://scim.ag/3EtS0US
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Forever grateful to the two wonderful female surgeons who saved my life in 2023
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10 months ago
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