Informative paper on MECOMr AML highlighting we have a lot of work to do! onlinelibrary.wiley.com/doi/10.1111/...

interesting study looking at the impact of various demographic features including SES in patients with AML in various eras of AML therapy haematologica.org/article/view...

This is what it looks like when ICE violates our First Amendment rights.

The current ACIP is not a credible committee. It pains me to say this, but do NOT listen to them for guidance on vaccines. I am an infectious disease doc and will be roundly ignoring their misinformed and anti-scientific guidelines. Yesterday's spectacle was an insult to vaccinology and science.

a huge thanks to a patient of mine who was willing to share his story with @theaacr.bsky.social regarding being treated with Aza + Ven + Revumenib as part of the BEAT AML study and to advocate for cancer research funding! cancerprogressreport.aacr.org/report/survi...

a study in @bloodjournals.hematology.org illustrating that ASXL1 mutations in CML are a bad actor! ashpublications.org/blood/articl...

Reading today’s big NYT Magazine story made me physically sick It details how Trump & the men he put in charge of federal research—men like Jay Bhattacharya & RFK Jr—are dismantling cancer research Not just the US vaccine system—they’re crushing cancer R&D 🎁Link www.nytimes.com/2025/09/14/m...

Reminder that our study investigating HMA + the LSD1 inhibitor iadademstat for accelerated/blast-phase MPNs is open to enrollment! clinicaltrials.gov/study/NCT066...

a fascinating @bloodjournals.hematology.org letter highlighting synergy between Bcl-xL inhibition and interferon use in MPNs! ashpublications.org/bloodadvance...

interesting pre-clinical work looking at venetoclax + ponatinib for asciminib-resistant CML! www.nature.com/articles/s41...

a study looking at paired samples of chronic-phase MPN and blast-phase! acsjournals.onlinelibrary.wiley.com/doi/full/10....

This is defensive rhetoric: every word is chosen to rebut some attack or criticism that Jeffries imagines the listener making. It’s intrinsically weak and pathetic. Offensive rhetoric would be: this is bad, this is outrageous, this is authoritarian. It rebuts by making the stronger case.

Thanks to @rubenmesamd.bsky.social for inviting me to speak about MPN-AP/BP at the 2025 MPN Carolinas Workshop!

The Supreme Court just greenlit Donald Trump gutting nearly $800 MILLION for medical treatments and cures. Congress approved this funding for a reason: it saves lives. This is disgraceful, and families will suffer.

useful study demonstrating that lower-intensity AML risk scores are not very effective when HMA + VEN is used in R/R AML but immunophenotyping is helpful! onlinelibrary.wiley.com/doi/10.1002/...

The perfect day for a post-clinic walk through campus

a very interesting @bloodjournals.hematology.org pre-clinical paper looking at tasquinomod in MPN-BP! ashpublications.org/bloodadvance...

Chicago looking incredible this week!

Back on the inpatient leukemia service for a 2-week stretch! I will be posting daily articles as usual! Day 1 - time to treatment with HMA + VEN in newly dx AML pubmed.ncbi.nlm.nih.gov/40702896/

Feeling inspired after the @ash.hematology.org Committee on Educational Affairs meeting!

1/ This is a long 🧵, so buckle up & I hope you read till the end. The HHS Secretary, is planning to remove all 16 members of the USPSTF the expert panel that decides which preventive services (cancer screenings, HIV prevention meds) must be covered by insurers under the Affordable Care Act.

Happy to share new work led by senior fellow Dr. Sam Yates! We found that time from diagnosis to treatment does not impact overall survival in pts w/ newly diagnosed AML treated with HMA + VEN! haematologica.org/article/view...

This is deeply shameful. Over 1,000 Palestinians have been killed while trying to get aid in the past 8 weeks. Israel must immediately cease these shootings & lift the blockade. Congress must pass the UNRWA Funding Emergency Restoration Act to help distribute aid in Gaza www.bbc.com/news/article...

thanks to @oncbrothers.bsky.social for having me on to discuss AML! oncbrothers.com/algo-aml-2025

helpful @bloodjournals.hematology.org study focusing on IDH1 and IDH2 as markers of MRD in AML! ashpublications.org/bloodadvance...

New paper in @bloodjournals.hematology.org focused on olutasidenib +/- azacitidine in IDH1m MDS ashpublications.org/bloodadvance...

An interesting article in Haematologica analyzing the characteristics of patients with AML who don't receive treatment -9% of pts with AML did not receive treatment (40/429) -most common reasons were pt pref (73%), med reasons/doc rec (25%) haematologica.org/article/view...

Stand up with ASH and #Fight4Hematology! 🩸💪 As executive orders threaten hematologic research and care of patients, ASH has created a new #Fight4Hematology Action Hub to keep you informed and involved. Learn how to protect #hematology: www.hematology.org/a...#Fight4Hematology!#Fight4Hematology#hematology:#HemeSky #MedSky

Very excited to share that I was selected for a 2025 National Cancer Institute Early Career Investigator Award! @uchicagocancer.bsky.social @uchicagomedicine.bsky.social reporter.nih.gov/search/OYXYV...

grateful to be a part of this comprehensive review led by @leivaorly.bsky.social focused on pulm HTN and HF in patients with MPNs! www.jacc.org/doi/10.1016/...

very interesting study on how JAK2 inhibition may select for RAS pathway mutations in MPNs! www.nature.com/articles/s41...

the 2025 ELN guidelines for CML are out! www.nature.com/articles/s41...

Got to see the incredible Ramy Youssef perform tonight!

A very practical retrospective report demonstrating limited benefit of phlebotomy in patients with secondary/idiopathic polycythemia! onlinelibrary.wiley.com/doi/10.1111/...

an excellent article looking at various subtypes of myeloid malignancies! -SF3B1 VAF matters for MDS subtypes -blast % doesn't matter for NPM1m; HR mutations impact outcome in NPM1m AML -molecular data helps to separate oligomonocytic CMML from MDS aacrjournals.org/bloodcancerd...

helpful report of asciminib in R/R Ph+ ALL! High rates of remission but limited overall survival pubmed.ncbi.nlm.nih.gov/40601900/

America is beautiful, contradictory, unfinished. I am proud of our country even as we constantly strive to make it better, to protect and deepen our democracy, to fulfill its promise for each and every person who calls it home. Happy Independence Day. No Kings in America.

So excited to share that @ash.hematology.org Self Assessment Program (SAP) 9th edition is out! I had the honor of serving as part of an incredible editorial team and co-author the MPN chapters ashpublications.org/books/book/1...

New paper in @bloodjournal.bsky.social reporting a score incorporating IPSS-M, EPO level, transfusion dependence to predict ESA response in LR-MDS ashpublications.org/blood/articl...

Really impossible to overstate how completely this guy has failed at every aspect of being an opposition leader over the past six months. Jeffries is a truly inspiring example for every soulless careerist who would rather be king of nothing than stand for anything decent in the world.

a very nice commentary in @bloodjournals.hematology.org on incorporation of fitness assessment into AML workup written by @uchicagocancer.bsky.social hem/onc fellow Sam Yates et al! ashpublications.org/bloodadvance...

Elderly and disabled people told Congress that cutting Medicaid could kill people and in response, they were arrested in their wheelchairs. What the hell are we doing?

A very useful study demonstrating the non-inferiority of IDAC (1.5g/m2) consolidation compared to HIDAC (3g/m2) in patients aged 18-60 with AML pubmed.ncbi.nlm.nih.gov/40552969/

excellent paper looking at molecular/cytogenetic features associated with hematologic progression of polycythemia vera! www.nature.com/articles/s41...

congrats to @rubenmesamd.bsky.social and all of the other honorees!

The Phase III VERONA trial of aza +/- ven for high-risk MDS did not meet its primary endpoint, another disappointing outcome for this disease! news.abbvie.com/2025-06-16-A...

A reminder to reporters, when historians look back on this moment with the president throwing himself a military parade and the people throwing No Kings rallies across America, the media sources raving about the former and sneering at the latter are going to be quoted by name. This is your legacy!

Do chemo + venetoclax regimens have efficacy in patients with MDS or AML previously treated with HMA+VEN? We found: -CR/CRi 39% (7/18) -6/18 pts proceeded to allo-HCT -most common regimen was HIDAC+MITO+VEN (n=11) w/ CR/CRi rate of 54% dx.doi.org/10.1002/jha2...

Starting two weeks on inpatient leukemia service! Will be sharing daily articles as usual Day 1 - outcomes of accelerated/blast-phase MPN in a modern cohort of patients www.ncbi.nlm.nih.gov/pubmed/38739...

I don't care if these monstrous ICE raids are a "federal operation". This is authoritarian violence, plain and simple. Just because Stephen Miller has kidnapping quotas for brown people he doesn't want to see on the street doesn't mean we have to think it's okay.