The beautiful, ever-expanding universe of viral proteins targeting nucleotide immune signals! Paper by @reneechang.bsky.social in @cp-molcell.bsky.social on a nucleotide sponge www.cell.com/molecular-ce... and preprint by @doudna-lab.bsky.social on viral nucleases www.biorxiv.org/content/10.1...

Excited to share my PhD work in the @kranzuschlab.bsky.social, out now in Molecular Cell @cp-molcell.bsky.social We discover Acb4, a new family of viral sponges that sequesters nucleotide immune signals and defines molecular features that enable ligand specificity. www.cell.com/molecular-ce...